{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:07:15Z","timestamp":1792789635901,"version":"4.5.0"},"reference-count":86,"publisher":"University of Toronto Press Inc. (UTPress)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiotherapy Canada"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p> Purpose: Pain is a significantly disabling problem that often interacts with other deficits during the rehabilitation process. The aim of this paper is to review evidence of interactions between pain and the motor cortex in order to attempt to answer the following questions: (1) Does acute pain interfere with motor-cortex activity? (2) Does chronic pain interfere with motor-cortex activity, and, conversely, does motor-cortex plasticity contribute to chronic pain? (3) Can the induction of motor plasticity by means of motor-cortex stimulation decrease pain? (4) Can motor training result in both motor-cortex reorganization and pain relief? <\/jats:p><jats:p> Summary of Key Points: Acute experimental pain has been clearly shown to exert an inhibitory influence over the motor cortex, which can interfere with motor learning capacities. Current evidence also suggests a relationship between chronic pain and motor-cortex reorganization, but it is still unclear whether one causes the other. However, there is growing evidence that interventions aimed at normalizing motor-cortex organization can lead to pain relief. <\/jats:p><jats:p> Conclusions: Interactions between pain and the motor cortex are complex, and more studies are needed to understand these interactions in our patients, as well as to develop optimal rehabilitative strategies. <\/jats:p>","DOI":"10.3138\/ptc.2010-08p","type":"journal-article","created":{"date-parts":[[2011,2,4]],"date-time":"2011-02-04T14:15:39Z","timestamp":1296828939000},"page":"305-314","source":"Crossref","is-referenced-by-count":64,"title":["Interactions between Pain and the Motor Cortex: Insights from Research on Phantom Limb Pain and Complex Regional Pain Syndrome"],"prefix":"10.3138","volume":"63","author":[{"given":"Catherine","family":"Mercier","sequence":"first","affiliation":[{"name":"Catherine Mercier, OT, PhD: Centre interdisciplinaire de recherche en r\u00e9adaptation et en int\u00e9gration sociale (CIRRIS) and D\u00e9partement de r\u00e9adaptation, Universit\u00e9 Laval, Quebec."},{"name":"Guillaume L\u00e9onard, PT, PhD: Centre interdisciplinaire de recherche en r\u00e9adaptation et en int\u00e9gration sociale (CIRRIS) and D\u00e9partement de r\u00e9adaptation, Universit\u00e9 Laval, Quebec."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"L\u00e9onard","sequence":"additional","affiliation":[{"name":"Catherine Mercier, OT, PhD: Centre interdisciplinaire de recherche en r\u00e9adaptation et en int\u00e9gration sociale (CIRRIS) and D\u00e9partement de r\u00e9adaptation, Universit\u00e9 Laval, Quebec."},{"name":"Guillaume L\u00e9onard, PT, PhD: Centre interdisciplinaire de recherche en r\u00e9adaptation et en int\u00e9gration sociale (CIRRIS) and D\u00e9partement de r\u00e9adaptation, Universit\u00e9 Laval, 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