{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T14:08:33Z","timestamp":1694700513713},"reference-count":18,"publisher":"The Japan Geriatrics Society","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jpn. j. geriat","Nippon Ronen Igakkai Zasshi","Nihon Ronen Igakkai Zasshi","Jpn J Geriat"],"published-print":{"date-parts":[[2017]]},"DOI":"10.3143\/geriatrics.54.375","type":"journal-article","created":{"date-parts":[[2017,8,28]],"date-time":"2017-08-28T22:04:41Z","timestamp":1503957881000},"page":"375-380","source":"Crossref","is-referenced-by-count":2,"title":["The use of direct-acting antivirals in the treatment of elderly patients with hepatitis C Virus infection"],"prefix":"10.3143","volume":"54","author":[{"given":"Kosuke","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Kanazawa University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuro","family":"Shimakami","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Kanazawa University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Kanazawa University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1704","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1) Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M: Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-362.","DOI":"10.1126\/science.2523562"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2) Kiyosawa K, Sodeyama T, Tanaka E, Gido Y, Yoshizawa K, Nakano Y, et al.: Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990; 12: 671-675.","DOI":"10.1002\/hep.1840120409"},{"key":"3","unstructured":"3) Farci P, Alter HJ, Wong D, Miller RH, Shih JW, Jett B, et al.: Along-term study of hepatitis C virus replication in non-A, non-B hepatitis. N Engl J Med 1991; 325: 98-104."},{"key":"4","unstructured":"4) Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, et al.: Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009; 41: 1105-1109."},{"key":"5","doi-asserted-by":"publisher","unstructured":"5) Lohmann V, K\u00f6rner F, Koch J, Herian U, Theilmann L, Bartenschlager R: Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 1999; 285: 110-113.","DOI":"10.1126\/science.285.5424.110"},{"key":"6","first-page":"2083","volume":"59","author":"H Kumada","year":"2014","unstructured":"6) Kumada H, Suzuki Y, Ikeda K, Toyota J, Karino Y, Chayama K, et al.: Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection. Hepatology 2014; 59: 2083-2091.","journal-title":"Hepatology","ISSN":"http:\/\/id.crossref.org\/issn\/0270-9139","issn-type":"print"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7) Sterling RK, Lissen E, Clumeck N, Sola R, Correa MC, Montaner J, et al.: Development of a simple noninvasive index to predict significant fibrosis in patients with HIV\/HCV coinfection. Hepatology 2006; 43: 1317-1325.","DOI":"10.1002\/hep.21178"},{"key":"8","unstructured":"11) Omata M, Nishiguchi S, Ueno Y, Mochizuki H, Izumi N, Ikeda F, et al.: Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial. J Viral Hepat 2014; 21: 762-768."},{"key":"9","unstructured":"12) Mizokami M, Yokosuka O, Takehara T, Sakamoto N, Korenaga M, Mochizuki H, et al.: Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial. Lancet Infect Dis 2015; 15: 645-653."},{"key":"10","doi-asserted-by":"publisher","unstructured":"13) Chayama K, Notsumata K, Kurosaki M, Sato K, Rodrigues L Jr, Setze C, et al.: Randomized trial of interferon- and ribavirin-free ombitasvir\/paritaprevir\/ritonavir in treatment-experienced hepatitis C virus-infected patients. Hepatology 2015; 61: 1523-1532.","DOI":"10.1002\/hep.27705"},{"key":"11","first-page":"1253","volume":"58","author":"Y Asahina","year":"2013","unstructured":"14) Asahina Y, Tsuchiya K, Nishimura T, Muraoka M, Suzuki Y, Tamaki N, et al.: \u03b1-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C. Hepatology 2013; 58: 1253-1262.","journal-title":"Hepatology","ISSN":"http:\/\/id.crossref.org\/issn\/0270-9139","issn-type":"print"},{"key":"12","unstructured":"15) Yoshida H, Shiratori Y, Moriyama M, Arakawa Y, Ide T, Sata M, et al.: Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of chirrotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy. Ann Intern Med 1994; 131: 174-181."},{"key":"13","doi-asserted-by":"publisher","unstructured":"16) Asahina Y, Tsuchiya K, Tamaki N, Hirayama I, Tanaka T, Sato M, et al.:  Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection. Hepatology 2010; 52: 518-527.","DOI":"10.1002\/hep.23691"},{"key":"14","unstructured":"17) Tokita H, Fukui H, Tanaka A, Kamitsukasa H, Yagura M, Harada H, et al.: Risk factors for the development of hepatocellular carcinoma among patients with chronic hepatitis C who achieved a sustained virological response to interferon therapy. J Gastroenterol Hepatol 2015; 20: 752-758."},{"key":"15","unstructured":"18) Kobayashi S, Takeda T, Enomoto M, Tamori A, Kawada N, Habu D, et al.: Development of hepatocellular carcinoma in patients with chronic hepatitis C who had a sustained virological response to interferon therapy: a multicenter, retrospective cohort study of 1124 patients. Liver Int 2017; 27: 186-191."},{"key":"16","unstructured":"19) Hirakawa M, Ikeda K, Arase Y, Kawamura Y, Yatsuji H, Hosaka T, et al.: Hepatocarcinogenesis following HCV RNA eradication by interferon in chronic hepatitis patients. Intern Med 2008; 47: 1637-1643."},{"key":"17","unstructured":"20) Hung CH, Lee CM, Wang JH, Hu TH, Chen CH, Lin CY, et al.: Impact of diabetes mellitus on incidence of hepatocellular carcinoma in chronic hepatitis C patients treated with interferon-based antiviral therapy. Int J Cancer 2011; 128: 2344-2352."},{"key":"18","unstructured":"21) Huang CF, Yeh ML, Tsai PC, Hsieh MH, Yang HL, Hsieh MY, et al.: Baseline gamma-glutamyl transferase levels strongly correlate with hepatocellular carcinoma development in non-cirrhotic patients with successful hepatitis C virus eradication. J Hepatol 2014; 61: 67-74."}],"container-title":["Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics"],"original-title":["\u9ad8\u9f62\u8005C\u578b\u6162\u6027\u809d\u75be\u60a3\u306b\u5bfe\u3059\u308b\u76f4\u63a5\u4f5c\u7528\u578b\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\uff08DAA\uff09\u306e\u4f7f\u7528\u7d4c\u9a13"],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/geriatrics\/54\/3\/54_54.375\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,9,2]],"date-time":"2017-09-02T04:44:58Z","timestamp":1504327498000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/geriatrics\/54\/3\/54_54.375\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.3143\/geriatrics.54.375","relation":{},"ISSN":["0300-9173"],"issn-type":[{"value":"0300-9173","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]}}}