{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T20:04:47Z","timestamp":1775592287618,"version":"3.50.1"},"reference-count":30,"publisher":"Asian Spine Journal (ASJ)","issue":"6","license":[{"start":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:00:00Z","timestamp":1609113600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Department of Rehabilitation, Spinal Cord Injury Centre, Military Hospital Kirkee, Pune, India"}],"content-domain":{"domain":["asianspinejournal.org"],"crossmark-restriction":true},"short-container-title":["Asian Spine J"],"published-print":{"date-parts":[[2021,12,31]]},"abstract":"<jats:p>Respiratory failure and chronic ventilator dependence in tetraplegics following cervical injuries located high on the spine (C1\u2013C3) constitute significant challenges in the rehabilitation of patients given the occurrence of repeated hospitalizations and an ever-increasing financial burden. A 30-year-old man presented with posttraumatic tetraplegia following an unstable injury at the C1\u2013C2 level with cord compression; he was managed by posterior stabilization and decompression followed by ventilator dependence and no rehabilitation until 6 months postinjury. We implanted phrenic nerve stimulator electrodes bilaterally for indirect diaphragm pacing by an implantable pulse generator that allowed for weaning from mechanical ventilation and spontaneous ventilator-free breathing at 20 weeks post-implantation and which facilitated post-tetraplegia rehabilitation. At 36 months after implantation, the patient is ventilator- free without any procedure-related complications or respiratory infections. Diaphragm pacing with phrenic nerve stimulation may be a way forward for ventilator-dependent tetraplegics in developing countries to pursue effective rehabilitation and improved quality of life.<\/jats:p>","DOI":"10.31616\/asj.2020.0227","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T07:03:21Z","timestamp":1608793401000},"page":"874-880","update-policy":"https:\/\/doi.org\/10.31616\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country"],"prefix":"10.31616","volume":"15","author":[{"given":"Vyom","family":"Sharma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haris","family":"Jafri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilanjan","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Dangi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohit","family":"Kataruka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16744","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200207000-00005"},{"key":"ref2","first-page":"187","volume-title":"Prolonged mechanical ventilation","author":"Epstein","year":"2006"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9993(94)90027-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1993.28"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2014.12.004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.012616"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.03.97"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2009.06.012"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.04.033"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2012.74"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3340\/jkns.2013.54.4.359"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10039-1115"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.246256"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/09638280601046302"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1980.53.3.0345"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2012(11)07"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198512000-00021"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(02)00997-7"},{"key":"ref19","volume-title":"","year":"1996"},{"key":"ref20","first-page":"932","volume-title":"Application of electrotherapy to noncardiac thoracic disorders","author":"Schechter","year":"1970"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198405033101804"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2010.07.008"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.06.050"},{"key":"ref24","volume-title":"","year":"2017"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2010.07.237"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100345"},{"key":"ref27","first-page":"48","volume-title":"Personal situation and situation at home of respiratory-dependent patients with tetraplegia: electronic versus mechanical ventilation","author":"Wolf","year":"2000"},{"key":"ref28","first-page":"457","volume-title":"Stimulation phrenique implantee","author":"Similowski","year":"2001"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2008.43"},{"key":"ref30","volume-title":"","year":"2019"}],"container-title":["Asian Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.asianspinejournal.org\/upload\/pdf\/asj-2020-0227.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.asianspinejournal.org\/journal\/view.php?doi=10.31616\/asj.2020.0227","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.asianspinejournal.org\/upload\/pdf\/asj-2020-0227.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T06:28:55Z","timestamp":1640068135000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.asianspinejournal.org\/journal\/view.php?doi=10.31616\/asj.2020.0227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"URL":"https:\/\/doi.org\/10.31616\/asj.2020.0227","relation":{},"ISSN":["1976-1902","1976-7846"],"issn-type":[{"value":"1976-1902","type":"print"},{"value":"1976-7846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,31]]},"assertion":[{"value":"2020-05-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-28","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}