{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T15:27:49Z","timestamp":1780673269114,"version":"3.54.1"},"reference-count":24,"publisher":"Asian Spine Journal (ASJ)","issue":"6","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["asianspinejournal.org"],"crossmark-restriction":true},"short-container-title":["Asian Spine J"],"published-print":{"date-parts":[[2021,12,31]]},"abstract":"<jats:p>Study Design: Cross-sectional study using radiological measurements.Purpose: To analyze the relationship between type 2 diabetes mellitus (DM) and bone mineral density (BMD) in postmenopausal women and to assess risk factors of osteoporotic vertebral compression fracture (OVCF) in postmenopausal diabetic women.Overview of Literature: Type 2 DM has negative effects on the quality of bone. Patients with type 2 DM have increased risk of hip and other fractures, but their vertebral fracture risk is controversial. There is a positive correlation between body mass index (BMI) and BMD. At the same time, obesity is the most important risk factor for type 2 DM.Methods: Consecutive patients whose BMD had been checked using dual-energy X-ray absorptiometry at Gwangmyung Sungae Hospital were recruited. Patients were divided into two groups according to the presence of type 2 DM. Risk factors of OVCF including age, BMI, current smoking status, current alcohol consumption, and presence of osteoporosis were analyzed separately in the type 2 DM group and control group.Results: A total of 1,130 patients were enrolled in this study. The mean age was 63.2 years. BMI was positively correlated with lumbar BMD in the control group (r =0.284) and in the diabetic group (r =0.302). In subgroup analysis, BMI and age were significant risk factors of OVCF in the type 2 DM group. In multiple linear regression analysis, type 2 DM (\u03b2 =0.035; 95% confidence interval [CI], 0.005\u20130.065; p =0.024) and BMI (\u03b2 =0.015; 95% CI, 0.012\u20130.018; p &lt;0.001) were positively correlated with lumbar BMD, and age was negatively correlated with BMD (\u03b2 =\u22120.006; 95% CI, \u22120.007 to \u22120.004; p &lt;0.001).Conclusions: BMI was positively correlated with lumbar BMD and was higher in type 2 diabetic patients. Age was negatively correlated with lumbar BMD.<\/jats:p>","DOI":"10.31616\/asj.2021.0099","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T02:15:12Z","timestamp":1632363312000},"page":"721-727","update-policy":"https:\/\/doi.org\/10.31616\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Relationship between Type 2 Diabetes Mellitus and Lumbar Bone Mineral Density in Postmenopausal Women"],"prefix":"10.31616","volume":"15","author":[{"given":"Chang-Yk","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gun-Youl","family":"Back","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Hwan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16744","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt093"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.31616\/asj.2020.0594"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.41.293"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1909-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2986-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.080323"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00774-016-0798-z"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(06)69703-1"},{"key":"ref9","first-page":"76","volume-title":"Monitoring tobacco use","year":"1998"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1993.tb02093.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650080915"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3454-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-2035-9"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-007-0025-x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.05.013"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-006-0087-0"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1763"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-016-3614-7"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-017-0224-0"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1863-y"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-015-0219-2"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1750405"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-017-4294-7"},{"key":"ref24","first-page":"769","volume-title":"Health related quality of life, reoperation rate and function in patients with diabetes mellitus and hip fracture: a 2 year follow-up study","author":"Ekstrom","year":"2013"}],"container-title":["Asian Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.asianspinejournal.org\/upload\/pdf\/asj-2021-0099.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.asianspinejournal.org\/journal\/view.php?doi=10.31616\/asj.2021.0099","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.asianspinejournal.org\/upload\/pdf\/asj-2021-0099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T06:27:24Z","timestamp":1640068044000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.asianspinejournal.org\/journal\/view.php?doi=10.31616\/asj.2021.0099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"URL":"https:\/\/doi.org\/10.31616\/asj.2021.0099","relation":{},"ISSN":["1976-1902","1976-7846"],"issn-type":[{"value":"1976-1902","type":"print"},{"value":"1976-7846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,31]]},"assertion":[{"value":"2021-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-28","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}