{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:35:41Z","timestamp":1773275741133,"version":"3.50.1"},"reference-count":30,"publisher":"Asian Spine Journal (ASJ)","issue":"4","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["asianspinejournal.org"],"crossmark-restriction":true},"short-container-title":["Asian Spine J"],"published-print":{"date-parts":[[2022,8,31]]},"abstract":"<jats:p>Study Design: Retrospective study.Purpose: To study the outcomes of two-level anterior cervical discectomy and fusion (2L-ACDF) versus hybrid total disc replacement (H-TDR) for cervical myeloradiculopathy.Overview of Literature: For bilevel disc issues of the cervical spine, 2L-ACDF has been a historical tool with numerous implants used at different time frames. Recent developments in total disc replacement at mobile level with fusion at a spondylotic level known as hybrid fixation have added a new armamentarium for such disorders.Methods: An analysis of 49 consecutive patients who underwent 2L-ACDF (n=22) and H-TDR (n=27) from January 1, 2014 to December 31, 2017 was performed. Data were studied as retrieved from InstaPACS ver. 4.0 (Mediff Technologies Pvt. Ltd., Bengaluru, India) and medical records.Results: Twenty-two patients with 2L-ACDF and 27 patients with H-TDR were included. The mean\u00b1standard deviation (SD) follow-up duration was 4.0\u00b11.5 years in H-TDR and 3.1\u00b11.1 years in 2L-ACDF. The mean\u00b1SD Neck Disability Index (NDI) decreased from 26.1\u00b17.6 to 6.5\u00b13.9 in the H-TDR group and from 27.6\u00b17.2 to 6.4\u00b14.8 in the 2L-ACDF group at final follow-up. Disc height at suprajacent level in the 2L-ACDF group was 4.12\u00b10.48 mm, 4.10\u00b10.45 mm, and 4.05\u00b10.48 mm preoperatively, at 1-year, and final follow-up, respectively. Disc height at supradjacent level in the H-TDR group was 4.28\u00b10.36 mm, 4.20\u00b10.32 mm, and 4.19\u00b10.34 mm preoperatively, at 1-year, and final follow-up, respectively.Conclusions: There was significantly improved NDI in both groups. Adjacent segment disc height loss was greater in the 2L-ACDF group than in H-TDR but not statistically significant (&lt;i&gt;p&lt;\/i&gt; =0.304). Supradjacent segment range of motion was greater in the 2L-ACDF group than in the H-TDR group (&lt;i&gt;p&lt;\/i&gt; =0.003). Both findings supported radiographic adjacent segment degeneration (ASD), but symptomatic ASD was absent in both groups.<\/jats:p>","DOI":"10.31616\/asj.2021.0209","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T06:14:21Z","timestamp":1637129661000},"page":"493-501","update-policy":"https:\/\/doi.org\/10.31616\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Two-Level Anterior Cervical Discectomy and Fusion versus Hybrid Total Disc Replacement for Bilevel Pathology with Cervical Radiculopathy\/Myelopathy: A Comparative Study with a Minimum 2-Year Follow-up in an Indian Population"],"prefix":"10.31616","volume":"16","author":[{"given":"Jeevan Kumar","family":"Sharma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalidindi Kalyan Kumar","family":"Varma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhinandan 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