{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:03:40Z","timestamp":1757617420605,"version":"3.44.0"},"reference-count":51,"publisher":"The Society for Free Radical Research Japan","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Biochem. Nutr."],"published-print":{"date-parts":[[2025]]},"DOI":"10.3164\/jcbn.25-80","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T18:07:22Z","timestamp":1747159642000},"page":"195-201","source":"Crossref","is-referenced-by-count":0,"title":["Influence of transarterial chemoembolization on serum opsonic activity in hepatocellular carcinoma measured by chemiluminescence"],"prefix":"10.3164","volume":"77","author":[{"given":"Satoshi","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Chinda","sequence":"additional","affiliation":[{"name":"Division of Endoscopy, Hirosaki University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misa","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Akimoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsu","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenta","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikara","family":"Iino","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Kakehata","sequence":"additional","affiliation":[{"name":"Department of Radiology, Graduate School of Medicine, Hirosaki University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiyasu","family":"Tsushima","sequence":"additional","affiliation":[{"name":"Department of Radiology, Graduate School of Medicine, Hirosaki University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Kakeda","sequence":"additional","affiliation":[{"name":"Department of Radiology, Graduate School of Medicine, Hirosaki University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotake","family":"Sakuraba","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1739","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Singal AG, Lampertico P, Nahon P. Epidemiology and surveillance for hepatocellular carcinoma: new trends. J Hepatol 2020; 72: 250\u2013261.","DOI":"10.1016\/j.jhep.2019.08.025"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Reig M, Forner A, Rimola J, et al. BCLC strategy for prognosis prediction and treatment recommendation: the 2022 update. J Hepatol 2022; 76: 681\u2013693.","DOI":"10.1016\/j.jhep.2021.11.018"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Yang XM, Yang XY, Wang XY, Gu YX. Influence of transcatheter arterial embolization on symptom distress and fatigue in liver cancer patients. World J Gastrointest Oncol 2024; 16: 810\u2013818.","DOI":"10.4251\/wjgo.v16.i3.810"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Liu Z, Li M, Jia Y, Zheng L, Chen L. Effect of perceived stress on psychological distress in hepatocellular carcinoma patients undergoing TACE: the mediating role of experiential avoidance and the moderating role of trait mindfulness. BMC Cancer 2025; 25: 254.","DOI":"10.1186\/s12885-025-13679-y"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Hassanin TM, Fouad Y, Hassnine A, Eisawy M, Farag N, Abdel Ghany W. Quality of life after transcatheter arterial chemoembolization combined with radiofrequency ablation in patients with unresectable hepatocellular carcinoma compared with transcatheter arterial chemoembolization alone. Asian Pac J Cancer Prev 2021; 22: 1255\u20131261.","DOI":"10.31557\/APJCP.2021.22.4.1255"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Yamada M, Suzuki K, Kudo S, et al. Effect of exhaustive exercise on human neutrophils in athletes. Luminescence 2000; 15: 15\u201320.","DOI":"10.1002\/(SICI)1522-7243(200001\/02)15:1<15::AID-BIO570>3.0.CO;2-O"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Abe T, Shimoyama T, Fukuda S, Nakaji S, Sugawara K, Saito Y. Effects of <i>Helicobacter pylori<\/i> in the stomach on neutrophil chemiluminescence in patients with gastric cancer. Luminescence 2000; 15: 267\u2013271.","DOI":"10.1002\/1522-7243(200009\/10)15:5<267::AID-BIO590>3.3.CO;2-5"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Suzuki H. Introduction to serial reviews: oxidative stress and digestive diseases. J Clin Biochem Nutr 2018; 63: 5.","DOI":"10.3164\/jcbn.17-intro"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Suzuki K, Sato H, Kikuchi T, et al. Capacity of circulating neutrophils to produce reactive oxygen species after exhaustive exercise. J Appl Physiol (1985) 1996; 81: 1213\u20131222.","DOI":"10.1152\/jappl.1996.81.3.1213"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Tsubakihara T, Umeda T, Takahashi I, et al. Effects of soccer matches on neutrophil and lymphocyte functions in female university soccer players. Luminescence 2013; 28: 129\u2013135.","DOI":"10.1002\/bio.2351"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Hasegawa H, Suzuki K, Nakaji S, Sugawara K. Analysis and assessment of the capacity of neutrophils to produce reactive oxygen species in a 96-well microplate format using lucigenin- and luminol-dependent chemiluminescence. J Immunol Methods 1997; 210: 1\u201310.","DOI":"10.1016\/S0022-1759(97)00159-2"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Chinda D, Shimoyama T, Arai T, et al. Usefulness of serum opsonic activity measured by chemiluminescence method to assess the invasiveness of colorectal endoscopic mucosal dissection. Free Radic Res 2020; 54: 810\u2013817.","DOI":"10.1080\/10715762.2019.1681590"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Arai T, Chinda D, Shimoyama T, et al. Influence of gastric endoscopic submucosal dissection on serum opsonic activity measured by chemiluminescence. J Clin Biochem Nutr 2019; 64: 180\u2013185.","DOI":"10.3164\/jcbn.18-93"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Saito D, Nakaji S, Umeda T, et al. Effects of long-distance running on serum opsonic activity measured by chemiluminescence. Luminescence 2003; 18: 122\u2013124.","DOI":"10.1002\/bio.438"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Kokot K, Schaefer RM, Teschner M, Gilge U, Plass R, Heidland A. Activation of leukocytes during prolonged physical exercise. Adv Exp Med Biol 1988; 240: 57\u201363.","DOI":"10.1007\/978-1-4613-1057-0_6"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Brozek J, Grande F, Anderson JT, Keys A. Densitometric analysis of body composition: revision of some quantitative assumptions. Ann N Y Acad Sci 1963; 110: 113\u2013140.","DOI":"10.1111\/j.1749-6632.1963.tb17079.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Flynn MG, Pizza FX, Boone JB Jr., Andres FF, Michaud TA, Rodriguez-Zayas JR. Indices of training stress during competitive running and swimming seasons. Int J Sports Med 1994; 15: 21\u201326.","DOI":"10.1055\/s-2007-1021014"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Kojima A, Umeda T, Saito K, et al. Effects of 2.5-hour sumo training on serum opsonic activity. Luminescence 2009; 24: 224\u2013229.","DOI":"10.1002\/bio.1104"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Kanda Y. Investigation of the freely available easy-to-use software \u2018EZR\u2019 for medical statistics. Bone Marrow Transplant 2013; 48: 452\u2013458.","DOI":"10.1038\/bmt.2012.244"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Burger D, Dayer JM. Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-\u03b1 production in contact-mediated activation of monocytes by T lymphocytes. Ann N Y Acad Sci 2002; 966: 464\u2013473.","DOI":"10.1111\/j.1749-6632.2002.tb04248.x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 Sato S, Nakaji S, Sawada K, et al. Association between reactive oxygen species production in neutrophils and liver fibrosis in the general population. J Clin Biochem Nutr 2023; 73: 214\u2013220.","DOI":"10.3164\/jcbn.23-46"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Mochida N, Umeda T, Yamamoto Y, et al. The main neutrophil and neutrophil-related functions may compensate for each other following exercise\u2014a finding from training in university judoists. Luminescence 2007; 22: 20\u201328.","DOI":"10.1002\/bio.922"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Takahashi I, Umeda T, Mashiko T, et al. Effects of rugby sevens matches on human neutrophil-related non-specific immunity. Br J Sports Med 2007; 41: 13\u201318.","DOI":"10.1136\/bjsm.2006.027888"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24 Kowatari K, Suzuki K, Kudo S, et al. Applicability of chemiluminescence to assess the degree of operative stress in patients undergoing spinal surgery. Luminescence 1999; 14: 331\u2013334.","DOI":"10.1002\/(SICI)1522-7243(199911\/12)14:6<331::AID-BIO556>3.0.CO;2-E"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 Savini I, Catani MV, Evangelista D, Gasperi V, Avigliano L. Obesity-associated oxidative stress: strategies finalized to improve redox state. Int J Mol Sci 2013; 14: 10497\u201310538.","DOI":"10.3390\/ijms140510497"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26 Manna P, Jain SK. Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies. Metab Syndr Relat Disord 2015; 13: 423\u2013444.","DOI":"10.1089\/met.2015.0095"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27 \u010colak E, Pap D. The role of oxidative stress in the development of obesity and obesity-related metabolic disorders. J Med Biochem 2021; 40: 1\u20139.","DOI":"10.5937\/jomb0-24652"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28 Winter JE, MacInnis RJ, Wattanapenpaiboon N, Nowson CA. BMI and all-cause mortality in older adults: a meta-analysis. Am J Clin Nutr 2014; 99: 875\u2013890.","DOI":"10.3945\/ajcn.113.068122"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Yu R, Wong M, Leung J, Lee J, Auyeung TW, Woo J. Incidence, reversibility, risk factors and the protective effect of high body mass index against sarcopenia in community-dwelling older Chinese adults. Geriatr Gerontol Int 2014; 14 Suppl 1: 15\u201328.","DOI":"10.1111\/ggi.12220"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30 Xu H, Brown JL, Bhaskaran S, Van Remmen H. Reactive oxygen species in the pathogenesis of sarcopenia. Free Radic Biol Med 2025; 227: 446\u2013458.","DOI":"10.1016\/j.freeradbiomed.2024.11.046"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31 Chen M, Wang Y, Deng S, Lian Z, Yu K. Skeletal muscle oxidative stress and inflammation in aging: focus on antioxidant and anti-inflammatory therapy. Front Cell Dev Biol 2022; 10: 964130.","DOI":"10.3389\/fcell.2022.964130"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32 Foreman NA, Hesse AS, Ji LL. Redox signaling and sarcopenia: searching for the primary suspect. Int J Mol Sci 2021; 22: 9045.","DOI":"10.3390\/ijms22169045"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33 Kasugai H, Kojima J, Tatsuta M, et al. Treatment of hepatocellular carcinoma by transcatheter arterial embolization combined with intraarterial infusion of a mixture of cisplatin and ethiodized oil. Gastroenterology 1989; 97: 965\u2013971.","DOI":"10.1016\/0016-5085(89)91505-9"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34 Takayasu K, Muramatsu Y, Maeda T, et al. Targeted transarterial oily chemoembolization for small foci of hepatocellular carcinoma using a unified helical CT and angiography system: analysis of factors affecting local recurrence and survival rates. AJR Am J Roentgenol 2001; 176: 681\u2013688.","DOI":"10.2214\/ajr.176.3.1760681"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35 Fujita K, Takuma K, Oura K, et al. Transarterial chemoembolization for patients with hepatocellular carcinoma using miriplatin without the need for hydration. Clin Transl Sci 2025; 18: e70182.","DOI":"10.1111\/cts.70182"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36 Hatanaka T, Kakizaki S, Shimada Y, et al. Early decreases in \u03b1-fetoprotein and des-\u03b3-carboxy prothrombin predict the antitumor effects of hepatic transarterial infusion chemotherapy with cisplatin (CDDP) powder in patients with advanced hepatocellular carcinoma. Intern Med 2016; 55: 2163\u20132171.","DOI":"10.2169\/internalmedicine.55.6688"},{"key":"37","unstructured":"37 Fukushima S, Kishimoto S, Hayashi Y, et al. Intra-hepatic artery infusional chemotherapy with cisplatin suspension in lipiodol (LPS) of hepatocellular carcinoma (I)\u2014preparation of LPS and its anticancer effect on a rabbit liver cancer model after injection into the hepatic artery. Nihon Gan Chiryo Gakkai Shi 1988; 23: 2743\u20132749. (in Japanese)"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38 Bouman A, Heineman MJ, Faas MM. Sex hormones and the immune response in humans. Hum Reprod Update 2005; 11: 411\u2013423.","DOI":"10.1093\/humupd\/dmi008"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39 Chiang K, Parthasarathy S, Santanam N. Estrogen, neutrophils and oxidation. Life Sci 2004; 75: 2425\u20132438.","DOI":"10.1016\/j.lfs.2004.04.035"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40 Molloy EJ, O&apos;Neill AJ, Grantham JJ, et al. Sex-specific alterations in neutrophil apoptosis: the role of estradiol and progesterone. Blood 2003; 102: 2653\u20132659.","DOI":"10.1182\/blood-2003-02-0649"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41 Skafar DF, Xu R, Morales J, Ram J, Sowers JR. Clinical review 91: female sex hormones and cardiovascular disease in women. J Clin Endocrinol Metab 1997; 82: 3913\u20133918.","DOI":"10.1210\/jc.82.12.3913"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42 Cannon JG, St Pierre BA. Gender differences in host defense mechanisms. J Psychiatr Res 1997; 31: 99\u2013113.","DOI":"10.1016\/S0022-3956(96)00055-6"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43 Wang X, Reape TJ, Li X, et al. Induced expression of adipophilin mRNA in human macrophages stimulated with oxidized low-density lipoprotein and in atherosclerotic lesions. FEBS Lett 1999; 462: 145\u2013150.","DOI":"10.1016\/S0014-5793(99)01521-5"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44 Fujii H, Ikura Y, Arimoto J, et al. Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning. J Atheroscler Thromb 2009; 16: 893\u2013901.","DOI":"10.5551\/jat.2055"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45 Northup PG, Sundaram V, Fallon MB, et al. Hypercoagulation and thrombophilia in liver disease. J Thromb Haemost 2008; 6: 2\u20139.","DOI":"10.1111\/j.1538-7836.2007.02772.x"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46 Valgimigli L, Valgimigli M, Gaiani S, Pedulli GF, Bolondi L. Measurement of oxidative stress in human liver by EPR spin-probe technique. Free Radic Res 2000; 33: 167\u2013178.","DOI":"10.1080\/10715760000300721"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47 Fujita N, Horiike S, Sugimoto R, et al. Hepatic oxidative DNA damage correlates with iron overload in chronic hepatitis C patients. Free Radic Biol Med 2007; 42: 353\u2013362.","DOI":"10.1016\/j.freeradbiomed.2006.11.001"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48 Michalak A, Lach T, Cicho\u017c-Lach H. Oxidative stress\u2014a key player in the course of alcohol-related liver disease. J Clin Med 2021; 10: 3011.","DOI":"10.3390\/jcm10143011"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49 Salete-Granado D, Carbonell C, Puertas-Miranda D, et al. Autophagy, oxidative stress, and alcoholic liver disease: a systematic review and potential clinical applications. Antioxidants (Basel) 2023; 12: 1425.","DOI":"10.3390\/antiox12071425"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50 Ma Y, Lee G, Heo SY, Roh YS. Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease. Antioxidants (Basel) 2021; 11: 91.","DOI":"10.3390\/antiox11010091"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51 Spahis S, Delvin E, Borys JM, Levy E. Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis. Antioxid Redox Signal 2017; 26: 519\u2013541.","DOI":"10.1089\/ars.2016.6776"}],"container-title":["Journal of Clinical Biochemistry and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jcbn\/77\/2\/77_25-80\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T04:22:17Z","timestamp":1757132537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jcbn\/77\/2\/77_25-80\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.3164\/jcbn.25-80","relation":{},"ISSN":["0912-0009","1880-5086"],"issn-type":[{"type":"print","value":"0912-0009"},{"type":"electronic","value":"1880-5086"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"25-80"}}