{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T07:22:48Z","timestamp":1761981768790,"version":"build-2065373602"},"reference-count":42,"publisher":"American Dairy Science Association","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":1654,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.3168\/jds.2013-7416","type":"journal-article","created":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T02:16:31Z","timestamp":1400206591000},"page":"4029-4042","source":"Crossref","is-referenced-by-count":5,"title":["Effect of commercial or depurinized milk on rat liver growth-regulatory kinases, nuclear factor-kappa B, and endonuclease in experimental hyperuricemia: Comparison with allopurinol therapy"],"prefix":"10.3168","volume":"97","author":[{"given":"G.","family":"Kocic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pavlovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Nikolic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Veljkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Panseri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.M.","family":"Chiesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Andjelkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Jevtovic-Stoimenov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Sokolovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Cvetkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Stojanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Kocic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Nikolic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1747","reference":[{"issue":"Suppl. A","key":"10.3168\/jds.2013-7416_bib0005","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1016\/j.placenta.2007.11.001","article-title":"Uric acid as a pathogenic factor in preeclampsia","volume":"29","author":"Bainbridge","year":"2008","journal-title":"Placenta"},{"key":"10.3168\/jds.2013-7416_bib0010","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1432-1033.1975.tb02292.x","article-title":"Hepatic nucleases 1. Method for the specific determination and characterization in rat liver","volume":"57","author":"Bartholeyns","year":"1975","journal-title":"Eur. J. Biochem."},{"key":"10.3168\/jds.2013-7416_bib0015","unstructured":"Carluccio, F., and G. Kocic. 2011. Procedimento technologico per de la producone di un alimentare dietetico composito a base di latte con livello ridoto di acido urico e purine e prodoto alimentare cosi ottenuto. F. Carluccio and G. Kocic, assignees. Italy patent IT2009PR00057 20090723."},{"key":"10.3168\/jds.2013-7416_bib0020","article-title":"Composite diethetic milk draught and method for production of composite milk draught with reduced level of uric acid and purine compounds","author":"Cencic","year":"2011","journal-title":"A. Cencic, assignee"},{"key":"10.3168\/jds.2013-7416_bib0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ijcard.2008.09.004","article-title":"Uric acid activates extracellular signal-regulated kinases and thereafter endothelin-1 expression in rat cardiac fibroblasts","volume":"139","author":"Cheng","year":"2010","journal-title":"Int. J. Cardiol."},{"key":"10.3168\/jds.2013-7416_bib0030","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/BF01974397","article-title":"Possible role of the acetone-inducible cytochrome P-450IIE1 in the metabolism and hepatotoxicity of thiobenzamide","volume":"64","author":"Chieli","year":"1990","journal-title":"Arch. Toxicol."},{"key":"10.3168\/jds.2013-7416_bib0035","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1056\/NEJMoa035700","article-title":"Purine-rich foods, dairy and protein intake, and the risk of gout in men","volume":"350","author":"Choi","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.3168\/jds.2013-7416_bib0040","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1136\/ard.2009.124230","article-title":"Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial","volume":"69","author":"Dalbeth","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"10.3168\/jds.2013-7416_bib0045","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.amjmed.2003.09.045","article-title":"Pathophysiology, clinical consequences, and treatment of tumor lysis syndrome","volume":"116","author":"Davidson","year":"2004","journal-title":"Am. J. Med."},{"key":"10.3168\/jds.2013-7416_bib0050","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/34112","article-title":"A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD","volume":"391","author":"Enari","year":"1998","journal-title":"Nature"},{"key":"10.3168\/jds.2013-7416_bib0055","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1056\/NEJMra0800885","article-title":"Uric acid and cardiovascular risk","volume":"359","author":"Feig","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.3168\/jds.2013-7416_bib0060","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00534-010-0304-2","article-title":"Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases","volume":"18","author":"Fujiyoshi","year":"2011","journal-title":"J. Hepatobiliary Pancreat. Sci."},{"key":"10.3168\/jds.2013-7416_bib0065","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00000372-198100340-00014","article-title":"Uric acid in the etiology of psoriasis","volume":"3","author":"Goldman","year":"1981","journal-title":"Am. J. Dermatopathol."},{"key":"10.3168\/jds.2013-7416_bib0070","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/j.cellsig.2011.05.004","article-title":"Akt signalling in health and disease","volume":"23","author":"Hers","year":"2011","journal-title":"Cell. Signal."},{"key":"10.3168\/jds.2013-7416_bib0075","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1139\/y87-367","article-title":"The role of biotransformation-detoxication in acetone-, 2-butanone-, and 2-hexanone-potentiated chloroform-induced hepatotoxicity","volume":"65","author":"Hewitt","year":"1987","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.3168\/jds.2013-7416_bib0080","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0378-4274(83)90190-X","article-title":"Relationship between the carbon skeleton length of ketonic solvents and potentiation of chloroform-induced hepatotoxicity in rats","volume":"16","author":"Hewitt","year":"1983","journal-title":"Toxicol. Lett."},{"key":"10.3168\/jds.2013-7416_bib0085","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.bbrc.2010.03.074","article-title":"Augmenter of liver regeneration causes different kinetics of ERK1\/2 and Akt\/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner","volume":"394","author":"Ilowski","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.3168\/jds.2013-7416_bib0090","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/jaoac\/87.1.116","article-title":"Determination of orotic acid, uric acid, and creatinine in milk by liquid chromatography","volume":"87","author":"Indyk","year":"2004","journal-title":"J. AOAC Int."},{"key":"10.3168\/jds.2013-7416_bib0095","doi-asserted-by":"crossref","first-page":"G1401","DOI":"10.1152\/ajpgi.00062.2008","article-title":"PI3K\/AKT activation is crucial for early hepatic regeneration after partial hepatectomy","volume":"294","author":"Jackson","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.3168\/jds.2013-7416_bib0100","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.nut.2003.09.005","article-title":"Diet\u2013disease gene interactions","volume":"20","author":"Kaput","year":"2004","journal-title":"Nutrition"},{"key":"10.3168\/jds.2013-7416_bib0105","unstructured":"Kocic, G., L. Marinkovic, S. Stojanovic, G. Nikolic, and D. Stojanovic. 2011. Adsorption filter device for production of depurinised milk. G. Kocic, assignee. Serbia patent RS 20100157(A) 2011-04-30."},{"key":"10.3168\/jds.2013-7416_bib0110","unstructured":"Kocic, G., G. Nikolic, D. Stojanovic, R. Pavlovic, T. Jevtovic-Stoimenov, D. Sokolovic, S. Stojanovic, S. Pajovic, and R. Kocic. 2010. Technological procedure for production of composite diethetic milk beverage draught with reduced level of uric acid and purine. G. Kocic, assignee. Serbia patent RS20090231 (A) 2010-12-31."},{"key":"10.3168\/jds.2013-7416_bib0115","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/j.1439-0396.2011.01191.x","article-title":"The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters","volume":"96","author":"Kocic","year":"2012","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl.)"},{"key":"10.3168\/jds.2013-7416_bib0120","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1080\/15216540600957438","article-title":"ERK1\/2 MAP Kinases in cell survival and apoptosis","volume":"58","author":"Lu","year":"2006","journal-title":"IUBMB Life"},{"key":"10.3168\/jds.2013-7416_bib0125","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1515\/BC.2002.212","article-title":"cis-4-Methylsphingosine phosphate induces apoptosis in neuroblastoma cells by opposite effects on p38 and ERK mitogen-activated protein kinases","volume":"383","author":"N\u00e4tzker","year":"2002","journal-title":"Biol. Chem."},{"key":"10.3168\/jds.2013-7416_bib0130","series-title":"Immunoassays: A Practical Approach","first-page":"239","article-title":"Data processing","author":"Nix","year":"2000"},{"key":"10.3168\/jds.2013-7416_bib0135","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1681\/ASN.2008010080","article-title":"Elevated uric acid increases the risk for kidney disease","volume":"19","author":"Obermayr","year":"2008","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.3168\/jds.2013-7416_bib0140","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.2337\/diabetes.52.12.2905","article-title":"Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement","volume":"52","author":"Ono","year":"2003","journal-title":"Diabetes"},{"key":"10.3168\/jds.2013-7416_bib0145","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.foodchem.2010.12.150","article-title":"A headspace solid-phase microextraction gas-chromatographic mass-spectrometric method (HS-SPME-GC\/MS) to quantify hexanal on butter during storage as marker of lipid oxidation","volume":"127","author":"Panseri","year":"2011","journal-title":"Food Chem."},{"key":"10.3168\/jds.2013-7416_bib0150","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/j.1365-2036.2011.04788.x","article-title":"Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease","volume":"34","author":"Petta","year":"2011","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.3168\/jds.2013-7416_bib0155","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1532-5415.1978.tb02396.x","article-title":"Serum uric acid and the renin-angiotensin system in hypertension","volume":"26","author":"Saito","year":"1978","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.3168\/jds.2013-7416_bib0160","first-page":"1","article-title":"The role of dietary nucleotides in single-stomached animals","volume":"13","author":"Sauer","year":"2011","journal-title":"Nutr. Res. Rev."},{"key":"10.3168\/jds.2013-7416_bib0165","doi-asserted-by":"crossref","first-page":"G322","DOI":"10.1152\/ajpgi.00597.2007","article-title":"Cultured rat hepatocytes upregulate Akt and ERK in an ErbB-2-dependent manner","volume":"295","author":"Scheving","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.3168\/jds.2013-7416_bib0170","unstructured":"Scientific Committee on Food. 1999. Opinion on an additional list of monomers and additives used in the manufacture of plastic materials intended to come into contact with foodstuffs until 21 March 1997. Reports of the scientific committee for food. 42nd Series. European Commission, Luxembourg."},{"key":"10.3168\/jds.2013-7416_bib0175","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/BF00220062","article-title":"A review of the molecular basis of hypoxanthine guanine phosphoribosyl transferase (HGPRT) deficiency","volume":"90","author":"Sculley","year":"1992","journal-title":"Hum. Genet."},{"key":"10.3168\/jds.2013-7416_bib0180","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/10408690490911756","article-title":"Milk biologically active components as nutraceuticals","volume":"45","author":"S\u00e9verin","year":"2005","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.3168\/jds.2013-7416_bib0185","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/jsfa.3466","article-title":"Determination of volatile compounds of precooked prawns (Penaeus vannamei) and cultured gilthead sea bream (Sparus aurata) stored in ice as possible spoilage markers using solid phase microextraction and gas chromatography\/mass spectrometry","volume":"89","author":"Soncin","year":"2009","journal-title":"J. Sci. Food Agric."},{"key":"10.3168\/jds.2013-7416_bib0190","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/rcm.2425","article-title":"Determination of phthalates in milk and milk products by liquid chromatography\/tandem mass spectrometry","volume":"20","author":"S\u00f8rensen","year":"2006","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.3168\/jds.2013-7416_bib0195","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3168\/jds.S0022-0302(84)81361-2","article-title":"Metabolites of nucleic acids in bovine milk","volume":"67","author":"Tiemeyer","year":"1984","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7416_bib0200","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/(SICI)1097-0274(199911)36:5<541::AID-AJIM6>3.0.CO;2-4","article-title":"Liver damage among shoe repairers","volume":"36","author":"Tomei","year":"1999","journal-title":"Am. J. Ind. Med."},{"key":"10.3168\/jds.2013-7416_bib0205","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1038\/sj.onc.1207556","article-title":"Mitogen-activated protein kinases in apoptosis regulation","volume":"23","author":"Wada","year":"2004","journal-title":"Oncogene"},{"key":"10.3168\/jds.2013-7416_bib0210","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S1043-2760(02)00662-8","article-title":"Role of Akt\/protein kinase B in metabolism","volume":"13","author":"Whiteman","year":"2002","journal-title":"Trends Endocrinol. Metab."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214003695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214003695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214003695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:17:46Z","timestamp":1731100666000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214003695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":42,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0022030214003695"],"URL":"https:\/\/doi.org\/10.3168\/jds.2013-7416","relation":{},"ISSN":["0022-0302"],"issn-type":[{"type":"print","value":"0022-0302"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}