{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:02:40Z","timestamp":1791385360119,"version":"4.3.3"},"reference-count":36,"publisher":"American Dairy Science Association","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":1592,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Boehringer Ingelheim"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.3168\/jds.2013-7569","type":"journal-article","created":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T19:12:56Z","timestamp":1403118776000},"page":"5401-5414","source":"Crossref","is-referenced-by-count":76,"title":["Efficacy of ampicillin trihydrate or ceftiofur hydrochloride for treatment of metritis and subsequent fertility in dairy cows"],"prefix":"10.3168","volume":"97","author":[{"given":"F.S.","family":"Lima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Vieira-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.S.F.M.","family":"Vasconcellos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.D.","family":"Mingoti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Karakaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Sol\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.S.","family":"Bisinotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Risco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.N.","family":"Galv\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.E.P.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2013-7569_bib0005","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.vetmic.2011.11.034","article-title":"Association between virulence factors of Escherichia coli Fusobacterium necrophorum, and Arcanobacterium pyogenes and uterine diseases of dairy cows","volume":"157","author":"Bicalho","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.3168\/jds.2013-7569_bib0010","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.theriogenology.2008.03.015","article-title":"Optimizing the accuracy of detecting a functional corpus luteum in dairy cows","volume":"70","author":"Bicalho","year":"2008","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7569_bib0015","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1177\/104063879300500407","article-title":"Microdilution antimicrobial susceptibilities of selected gram-negative veterinary bacterial isolates","volume":"5","author":"Burrows","year":"1993","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.3168\/jds.2013-7569_bib0020","series-title":"Basic and Clinical Pharmacology","first-page":"726","article-title":"Beta-lactam and other cell wall and membrane-active antibiotics","author":"Chambers","year":"2007"},{"key":"10.3168\/jds.2013-7569_bib0025","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.3168\/jds.2010-4075","article-title":"The association of serum metabolites with clinical disease during the transition period","volume":"94","author":"Chapinal","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0030","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.2460\/javma.2004.224.1634","article-title":"Efficacy of ceftiofur hydrochloride administered parenterally for the treatment of acute postpartum metritis in dairy cows","volume":"224","author":"Chenault","year":"2004","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.3168\/jds.2013-7569_bib0035","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1111\/j.1365-2958.1990.tb00537.x","article-title":"Molecular evolution of ubiquitous beta-lactamases towards extended-spectrum enzymes active against newer beta-lactam antibiotics","volume":"4","author":"Collatz","year":"1990","journal-title":"Mol. Microbiol."},{"key":"10.3168\/jds.2013-7569_bib0040","doi-asserted-by":"crossref","first-page":"3431","DOI":"10.3168\/jds.S0022-0302(06)72380-3","article-title":"Ceftiofur derivatives in serum, uterine tissues, cotyledons, and lochia after fetal membrane retention","volume":"89","author":"Drillich","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0045","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.3168\/jds.S0022-0302(01)74644-9","article-title":"Evaluation of a systemic antibiotic treatment of toxic puerperal metritis in dairy cows","volume":"84","author":"Drillich","year":"2001","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0050","doi-asserted-by":"crossref","first-page":"5225","DOI":"10.3168\/jds.2010-3428","article-title":"Definitions and diagnosis of postpartum endometritis in dairy cows","volume":"93","author":"Dubuc","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0055","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.3168\/jds.2010-3757","article-title":"Randomized clinical trial of antibiotic and prostaglandin treatments for uterine health and reproductive performance in dairy cows","volume":"94","author":"Dubuc","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0060","unstructured":"Elanco Animal Health. 2009. The 5-point body condition scoring system. Bulletin AI 10752. Elanco Animal Health, Greenfield, IN."},{"key":"10.3168\/jds.2013-7569_bib0065","unstructured":"FDA (Food and Drug Administration). 1998. Center for Veterinary Medicine: Approved Animal Drug Products. Accessed Jul. 11, 2013. http:\/\/www.accessdata.fda.gov\/scripts\/animaldrugsatfda\/details.cfm?dn=200-180."},{"key":"10.3168\/jds.2013-7569_bib0070","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein dairy cattle","volume":"77","author":"Ferguson","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0075","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.3168\/jds.2008-1615","article-title":"Effect of intrauterine infusion of ceftiofur on uterine health and fertility in dairy cows","volume":"92","author":"Galv\u00e3o","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0080","doi-asserted-by":"crossref","first-page":"108","DOI":"10.2460\/ajvr.2005.66.108","article-title":"Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle","volume":"66","author":"Gehring","year":"2005","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2013-7569_bib0085","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.theriogenology.2005.04.022","article-title":"Incidence of endometritis and its effects on reproductive performance of dairy cows","volume":"64","author":"Gilbert","year":"2005","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7569_bib0090","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1016\/j.theriogenology.2006.07.017","article-title":"Evaluation of intrauterine antibiotic treatment of clinical metritis and retained fetal membranes in dairy cows","volume":"66","author":"Goshen","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7569_bib0095","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0093-691X(74)90052-1","article-title":"Non-specific uterine infection and bovine fertility. I. Infection patterns and endometritis during the first seven weeks post-partum","volume":"1","author":"Griffin","year":"1974","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7569_bib0100","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1089\/fpd.2006.3.355","article-title":"Analysis of fecal microbial flora for antibiotic resistance in ceftiofur-treated calves","volume":"3","author":"Jiang","year":"2006","journal-title":"Foodborne Pathog. Dis."},{"key":"10.3168\/jds.2013-7569_bib0105","doi-asserted-by":"crossref","first-page":"3927","DOI":"10.3168\/jds.S0022-0302(03)74001-6","article-title":"In vitro antimicrobial susceptibility of Escherichia coli isolates from clinical bovine mastitis in Finland and Israel","volume":"86","author":"Lehtolainen","year":"2003","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0110","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.3168\/jds.2013-6850","article-title":"Effects of one or two treatments with prostaglandin F2\u03b1 on subclinical endometritis and fertility in lactating dairy cows inseminated by timed AI","volume":"96","author":"Lima","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0115","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.tvjl.2009.12.010","article-title":"Sensitivity to antibiotics of Arcanobacterium pyogenes and Escherichia coli from the uteri of cows with metritis\/endometritis","volume":"187","author":"Malinowski","year":"2011","journal-title":"Vet. J."},{"key":"10.3168\/jds.2013-7569_bib0120","doi-asserted-by":"crossref","first-page":"7158","DOI":"10.3168\/jds.2012-5812","article-title":"Evaluation of peripartal calcium status, energetic profile and neutrophil function in dairy cows at low or high risk of developing uterine disease","volume":"95","author":"Martinez","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0125","doi-asserted-by":"crossref","first-page":"4363","DOI":"10.3168\/jds.2011-5111","article-title":"Evaluation of two doses of ceftiofur crystalline free acid sterile suspension for treatment of metritis in lactation dairy cows","volume":"95","author":"McLaughlin","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7569_bib0130","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/vr.124.21.563","article-title":"Bovine uterine flora postpartum: A comparison of swabbing and biopsy","volume":"124","author":"Noakes","year":"1989","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2013-7569_bib0135","series-title":"Nutrient Requirements of Dairy Cattle","year":"2001"},{"key":"10.3168\/jds.2013-7569_bib0140","series-title":"Antimicrobial Therapy in Veterinary Medicine","first-page":"74","article-title":"Beta-lactam antibiotics: Penam penicillins","author":"Prescott","year":"1993"},{"key":"10.3168\/jds.2013-7569_bib0145","series-title":"Milk production and reproductive performance in postpartum dairy cows diagnosed and treated for metritis using a health monitoring program","author":"Rabaglino","year":"2009"},{"key":"10.3168\/jds.2013-7569_bib0150","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1017\/S0022029912000519","article-title":"A critical evaluation of diagnostics methods used to identify dairy cows with acute post-partum metritis in the current literature","volume":"79","author":"Sannmann","year":"2012","journal-title":"J. Dairy Res."},{"key":"10.3168\/jds.2013-7569_bib0155","first-page":"387","article-title":"Applying nutrition and physiology to improve reproduction in dairy cattle","volume":"67","author":"Santos","year":"2010","journal-title":"Soc. Reprod. Fertil. Suppl."},{"key":"10.3168\/jds.2013-7569_bib0160","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1136\/vr.155.13.383","article-title":"Minimum inhibitory concentrations of some antimicrobial drugs against bacteria causing uterine infections in cattle","volume":"155","author":"Sheldon","year":"2004","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2013-7569_bib0165","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7569_bib0170","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1530\/rep.0.1230837","article-title":"Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle","volume":"123","author":"Sheldon","year":"2002","journal-title":"Reproduction"},{"key":"10.3168\/jds.2013-7569_bib0175","first-page":"166","article-title":"Susceptibility of Fusobacterium necrophorum to antimicrobials. Part I: As determined by the disc method","volume":"41","author":"Simon","year":"1977","journal-title":"Can. J. Comp. Med."},{"key":"10.3168\/jds.2013-7569_bib0180","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.2460\/ajvr.67.10.1696","article-title":"Association between ceftiofur use and isolation of Escherichia coli with reduced susceptibility to ceftriaxone from fecal samples of dairy cows","volume":"67","author":"Tragesser","year":"2006","journal-title":"Am. J. Vet. Res."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214004299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214004299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214004299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T16:23:45Z","timestamp":1731083025000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214004299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0022030214004299"],"URL":"https:\/\/doi.org\/10.3168\/jds.2013-7569","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]}}}