{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:17:13Z","timestamp":1791206233612,"version":"4.1.0"},"reference-count":42,"publisher":"American Dairy Science Association","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T00:00:00Z","timestamp":1547596800000},"content-version":"vor","delay-in-days":1629,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.3168\/jds.2013-7802","type":"journal-article","created":{"date-parts":[[2014,6,7]],"date-time":"2014-06-07T03:30:20Z","timestamp":1402111820000},"page":"4907-4921","source":"Crossref","is-referenced-by-count":47,"title":["Effects of supplemental progesterone after artificial insemination on expression of interferon-stimulated genes and fertility in dairy cows"],"prefix":"10.3168","volume":"97","author":[{"suffix":"Jr.","given":"P.L.J.","family":"Monteiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.S.","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.P.","family":"Maciel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.L.G.","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"E.","family":"Sol\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.S.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.S.","family":"Bisinotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.W.","family":"Thatcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.E.P.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2013-7802_bib0005","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.3168\/jds.2012-6038","article-title":"Targeted progesterone supplementation improves fertility in lactating dairy cows without a corpus luteum at the initiation of the timed artificial insemination protocol","volume":"96","author":"Bisinotto","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0010","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1071\/RD07204","article-title":"Effect of increasing progesterone concentration from day 3 of pregnancy on subsequent embryo survival and development in beef heifers","volume":"20","author":"Carter","year":"2008","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2013-7802_bib0015","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1095\/biolreprod.109.082354","article-title":"Effect of elevated circulating progesterone on bovine blastocyst developmental and global transcriptome following endoscopic transfer of in vitro produced embryos to the bovine oviduct","volume":"83","author":"Carter","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2013-7802_bib0020","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.anireprosci.2007.12.005","article-title":"Progesterone concentration, follicular development and induction of cyclicity in dairy cows receiving intravaginal progesterone inserts","volume":"110","author":"Cerri","year":"2009","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2013-7802_bib0025","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1530\/REP-08-0242","article-title":"Period of dominance of the ovulatory follicle influences embryo quality in lactating dairy cows","volume":"137","author":"Cerri","year":"2009","journal-title":"Reproduction"},{"key":"10.3168\/jds.2013-7802_bib0030","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1530\/REP-09-0152","article-title":"Progesterone and conceptus elongation in cattle: A direct effect on the embryo or an indirect effect via the endometrium?","volume":"138","author":"Clemente","year":"2009","journal-title":"Reproduction"},{"key":"10.3168\/jds.2013-7802_bib0035","unstructured":"Elanco Animal Health. 2009. The 5-point body condition scoring system. Bulletin AI 10752. Elanco Animal Health, Greenfield, IN."},{"key":"10.3168\/jds.2013-7802_bib0040","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1095\/biolreprod43.2.210","article-title":"Expression of trophoblastic interferon genes in sheep and cattle","volume":"43","author":"Farin","year":"1990","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2013-7802_bib0045","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","author":"Ferguson","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0050","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1095\/biolreprod.108.074336","article-title":"Progesterone-regulated changes endometrial gene expression contribute to advanced conceptus development in cattle","volume":"81","author":"Forde","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2013-7802_bib0055","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1095\/biolreprod.108.069468","article-title":"Receptor transporter protein 4 (RTP4) in endometrium, ovary, and peripheral blood leukocytes of pregnant and cyclic ewes","volume":"79","author":"Gifford","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2013-7802_bib0060","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3168\/jds.S0022-0302(07)72628-0","article-title":"Regulation of interferon-stimulated genes in peripheral blood leukocytes in pregnant and bred, nonpregnant dairy cows","volume":"90","author":"Gifford","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0065","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.2527\/2003.8161552x","article-title":"Expression of the uterine Mx protein in cyclic and pregnant cows, gilts, and mares","volume":"81","author":"Hicks","year":"2003","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2013-7802_bib0070","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1530\/jrf.0.0670473","article-title":"Modification of the embryo maternal relationship in ewes by progesterone treatment early in the estrous-cycle","volume":"67","author":"Lawson","year":"1983","journal-title":"J. Reprod. Fertil."},{"key":"10.3168\/jds.2013-7802_bib0075","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.3168\/jds.2013-7802_bib0080","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.tvjl.2004.12.005","article-title":"Effects of time of progesterone supplementation on embryo development and interferon-tau production in the cow","volume":"171","author":"Mann","year":"2006","journal-title":"Vet. J."},{"key":"10.3168\/jds.2013-7802_bib0085","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1439-0531.1999.tb01250.x","article-title":"The influence of progesterone during early pregnancy in cattle","volume":"34","author":"Mann","year":"1999","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2013-7802_bib0090","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1477-7827-10-21","article-title":"Relationship between quantity of IFNT estimated by IFN-stimulated gene expression in peripheral blood mononuclear cells and bovine embryonic mortality after AI or ET","volume":"10","author":"Matsuyama","year":"2012","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.3168\/jds.2013-7802_bib0095","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.3168\/jds.S0022-0302(95)76817-5","article-title":"Extension of corpus luteum lifespan and reduction of uterine secretion of prostaglandin F2\u03b1 cows in response to recombinant interferon-tau","volume":"78","author":"Meyer","year":"1995","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0100","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1071\/RD12104","article-title":"Effects of treatment with human chorionic gonadotrophin or intravaginal progesterone-releasing device after AI on circulating progesterone concentrations in lactating dairy cows","volume":"25","author":"Nascimento","year":"2013","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2013-7802_bib0105","unstructured":"NRC. 2001. Nutrient Requirements of Dairy Cattle. 7th rev. ed., Washington, DC."},{"key":"10.3168\/jds.2013-7802_bib0110","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1210\/en.2007-0863","article-title":"Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein","volume":"149","author":"Oliveira","year":"2008","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2013-7802_bib0115","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1600-0897.2010.00912.x","article-title":"Effects of early conceptus signals on circulating immune cells: Lessons from domestic ruminants","volume":"64","author":"Ott","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.3168\/jds.2013-7802_bib0120","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.3168\/jds.2011-4498","article-title":"Relationship between pregnancy per artificial insemination and early luteal concentrations of progesterone and establishment of repeatability estimates for these traits in Holstein-Friesian heifers","volume":"95","author":"Parr","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0125","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0034-5288(93)90100-T","article-title":"Liver blood flow and metabolic clearance rate of progesterone in sheep","volume":"55","author":"Parr","year":"1993","journal-title":"Res. Vet. Sci."},{"key":"10.3168\/jds.2013-7802_bib0130","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.1073\/pnas.0501700102","article-title":"Relationship between follicle size at insemination and pregnancy success","volume":"102","author":"Perry","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.3168\/jds.2013-7802_bib0135","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0168-3659(02)00288-2","article-title":"Reengineering of a commercially available bovine intravaginal insert (CIDR insert) containing progesterone","volume":"85","author":"Rathbone","year":"2002","journal-title":"J. Control Release"},{"key":"10.3168\/jds.2013-7802_bib0140","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1095\/biolreprod.113.114694","article-title":"Low doses of bovine somatotropin enhance conceptus development and fertility in lactating dairy cows","volume":"90","author":"Ribeiro","year":"2014","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2013-7802_bib0145","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1053\/plac.1998.0381","article-title":"Trophoblast interferons","volume":"20","author":"Roberts","year":"1999","journal-title":"Placenta"},{"key":"10.3168\/jds.2013-7802_bib0150","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.3168\/jds.2009-2870","article-title":"Effect of reducing the period of follicle dominance in a timed artificial insemination protocol on reproduction of dairy cows","volume":"93","author":"Santos","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0155","doi-asserted-by":"crossref","first-page":"905","DOI":"10.3168\/jds.S0022-0302(04)73235-X","article-title":"Comparison of ovarian function and circulating steroids in estrous cycles of Holstein heifers and lactating cows","volume":"87","author":"Sartori","year":"2004","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0160","doi-asserted-by":"crossref","first-page":"4623","DOI":"10.3168\/jds.2007-0172","article-title":"Supplementation with estradiol-17\u03b2 before the last gonadotropin-releasing hormone injection of the Ovsynch protocol in lactating dairy cows","volume":"90","author":"Souza","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0165","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1071\/RD06102","article-title":"Pregnancy recognition and conceptus implantation in domestic ruminants: Roles of progesterone, interferons and endogenous retroviruses","volume":"19","author":"Spencer","year":"2007","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2013-7802_bib0170","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3168\/jds.S0022-0302(07)72634-6","article-title":"Interventions after artificial insemination: Conception rates, pregnancy survival, and ovarian responses to gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone","volume":"90","author":"Stevenson","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2013-7802_bib0175","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.theriogenology.2005.02.007","article-title":"Post-insemination milk progesterone concentration and embryo survival in dairy cows","volume":"64","author":"Stronge","year":"2005","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7802_bib0180","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00705-013-1673-z","article-title":"Progesterone suppresses interferon signaling by repressing TLR-7 and MxA expression in peripheral blood mononuclear cells of patients infected with hepatitis C virus","volume":"158","author":"Tayel","year":"2013","journal-title":"Arch. Virol."},{"key":"10.3168\/jds.2013-7802_bib0185","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0093-691X(96)00284-1","article-title":"Effects of administering progesterone at selected intervals after insemination of synchronized heifers on pregnancy rates and resynchronization of returns to service","volume":"46","author":"Van Cleeff","year":"1996","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7802_bib0190","doi-asserted-by":"crossref","first-page":"RESEARCH34","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"key":"10.3168\/jds.2013-7802_bib0195","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0093-691X(01)00565-9","article-title":"Reduction in size of the ovulatory follicle reduces subsequent luteal size and pregnancy rate","volume":"56","author":"Vasconcelos","year":"2001","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2013-7802_bib0200","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1530\/REP-06-0133","article-title":"Quantitative analysis of changes in endometrial gland morphology during the bovine oestrous cycle and their association with progesterone levels","volume":"134","author":"Wang","year":"2007","journal-title":"Reproduction"},{"key":"10.3168\/jds.2013-7802_bib0205","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1071\/RD11913","article-title":"Improving fertility to timed artificial insemination by manipulation of circulating progesterone concentrations in lactating dairy cattle","volume":"24","author":"Wiltbank","year":"2011","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2013-7802_bib0210","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2105-7-85","article-title":"Statistical analysis of real-time PCR data","volume":"7","author":"Yuan","year":"2006","journal-title":"BMC Bioinformatics"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214003968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214003968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214003968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:22:53Z","timestamp":1731100973000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214003968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":42,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0022030214003968"],"URL":"https:\/\/doi.org\/10.3168\/jds.2013-7802","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}