{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:28:13Z","timestamp":1791404893431,"version":"4.3.3"},"reference-count":31,"publisher":"American Dairy Science Association","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":1439,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Canadian Agriculture Adaptation Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.3168\/jds.2014-8564","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T10:34:12Z","timestamp":1418380452000},"page":"987-998","source":"Crossref","is-referenced-by-count":67,"title":["Enhanced early-life nutrition promotes hormone production and reproductive development in Holstein bulls"],"prefix":"10.3168","volume":"98","author":[{"given":"Alysha","family":"Dance","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Thundathil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy","family":"Wilde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Blondin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kastelic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2014-8564_bib0005","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.3168\/jds.S0022-0302(83)82135-3","article-title":"Endocrine changes associated with onset of spermatogenesis in Holstein bulls","volume":"66","author":"Amann","year":"1983","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2014-8564_bib0010","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3168\/jds.S0022-0302(74)84836-8","article-title":"Sperm production of Holstein bulls determined from testicular spermatid reserves, after cannulation of rete testis or vas deferens, and by daily ejaculation","volume":"57","author":"Amann","year":"1974","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2014-8564_bib0015","doi-asserted-by":"crossref","first-page":"433","DOI":"10.2527\/jas1983.572433x","article-title":"Changes in the pituitary-gonadal axis associated with puberty in Holstein bulls","volume":"57","author":"Amann","year":"1983","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2014-8564_bib0020","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1095\/biolreprod34.1.71","article-title":"Prepubertal changes in the hypothalamic-pituitary axis of Holstein bulls","volume":"34","author":"Amann","year":"1986","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2014-8564_bib0025","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0093-691X(98)00009-0","article-title":"Caliper and ultrasonographic measurements of bovine testicles and a mathematical formula for determining testicular volume and weight in vivo","volume":"49","author":"Bailey","year":"1998","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0030","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.theriogenology.2008.05.031","article-title":"The effect of nutrition on sexual development of bulls","volume":"70","author":"Barth","year":"2008","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1530\/reprod\/120.1.1","article-title":"Metabolic factors affecting the reproductive axis in male sheep","volume":"120","author":"Blache","year":"2000","journal-title":"J. Reprod. Fertil."},{"key":"10.3168\/jds.2014-8564_bib0040","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1530\/REP-06-0353","article-title":"Effect of feed restriction during calfhood on serum concentrations of metabolic hormones, gonadotropins, testosterone, and on sexual development in bulls","volume":"134","author":"Brito","year":"2007","journal-title":"Reproduction"},{"key":"10.3168\/jds.2014-8564_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.domaniend.2006.04.001","article-title":"Effect of nutrition during calfhood and peripubertal period on serum metabolic hormones, gonadotropins and testosterone concentrations, and on sexual development in bulls","volume":"33","author":"Brito","year":"2007","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.3168\/jds.2014-8564_bib0050","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.domaniend.2006.09.004","article-title":"Effect of improved nutrition during calfhood on serum metabolic hormones, gonadotropins, and testosterone concentrations, and on testicular development in bulls","volume":"33","author":"Brito","year":"2007","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.3168\/jds.2014-8564_bib0055","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.theriogenology.2012.01.022","article-title":"Testicular ultrasonogram pixel intensity during sexual development and its relationship with semen quality, sperm production, and quantitative testicular histology in beef bulls","volume":"78","author":"Brito","year":"2012","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0060","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0303-7207(90)90091-L","article-title":"Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells","volume":"69","author":"Cailleau","year":"1990","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.3168\/jds.2014-8564_bib0065","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.2527\/jas1982.5361645x","article-title":"Testicular development and establishment of spermatogenesis in Holstein bulls","volume":"53","author":"Curtis","year":"1981","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2014-8564_bib0070","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.0953-8194.2004.01149.x","article-title":"The hypothalamic insulin-like growth factor-1 receptor and its relationship to gonadotropin-releasing hormones neurones during postnatal development","volume":"16","author":"Daftary","year":"2004","journal-title":"J. Neuroendocrinol."},{"key":"10.3168\/jds.2014-8564_bib0075","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0093-691X(96)00190-2","article-title":"Changes in circulating hormone concentrations, testes histology and testes ultrasonography during sexual maturation in beef bulls","volume":"46","author":"Evans","year":"1996","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0080","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0093-691X(94)00062-Y","article-title":"Differences in early patterns of gonadotropin secretion between early and late maturing bulls, and changes in semen characteristics at puberty","volume":"43","author":"Evans","year":"1995","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0085","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0093-691X(98)00129-0","article-title":"Computer analysis of video and ultrasonographic images for evaluation of bull testes","volume":"50","author":"G\u00e1bor","year":"1998","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2014-8564_bib0090","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1095\/biolreprod40.6.1321","article-title":"Insulin-like growth factor I in the developing and mature rat testis: Immunohistochemical aspects","volume":"40","author":"Hansson","year":"1989","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2014-8564_bib0095","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1210\/endo.137.9.8756538","article-title":"Insulin-like growth factor I of peripheral origin acts centrally to accelerate the initiation of female puberty","volume":"137","author":"Hiney","year":"1996","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2014-8564_bib0100","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2164\/jandrol.109.008680","article-title":"Deletion of the IGF1 gene: Suppressive effects on adult Leydig cell development","volume":"31","author":"Hu","year":"2010","journal-title":"J. Androl."},{"key":"10.3168\/jds.2014-8564_bib0105","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.3168\/jds.S0022-0302(02)74391-9","article-title":"Effects of ad libitum milk intake on dairy calves","volume":"85","author":"Jasper","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2014-8564_bib0110","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/0006-291X(86)90317-7","article-title":"Direct stimulatory effects of insulin-like growth factor-I on Leydig cell steroidogenesis in primary culture","volume":"137","author":"Lin","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.3168\/jds.2014-8564_bib0115","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.2527\/jas1978.4641054x","article-title":"Puberty in beef bulls: Hormone concentrations, growth, testicular development, sperm production and sexual aggressiveness in bulls of different breeds","volume":"46","author":"Lunstra","year":"1978","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2014-8564_bib0120","series-title":"Nutrient Requirements of Dairy Cattle","year":"2001"},{"key":"10.3168\/jds.2014-8564_bib0125","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1439-0531.2008.01177.x","article-title":"Sexual maturation in the bull","volume":"43","author":"Rawlings","year":"2008","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2014-8564_bib0130","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1095\/biolreprod19.5.1108","article-title":"Plasma luteinizing hormone (LH) and testosterone levels during sexual maturation in beef bull calves","volume":"19","author":"Rawlings","year":"1978","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2014-8564_bib0135","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3181\/0708-RM-212","article-title":"Insulin-like growth factor 1 is expressed in mouse developing testis and regulates somatic cell proliferation","volume":"233","author":"Villalpando","year":"2008","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.3168\/jds.2014-8564_bib0140","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1095\/biolreprod.103.022590","article-title":"Development of Leydig cells in the insulin-like growth factor-I (IGF-I) knockout mouse: Effects of IGF-I replacement and gonadotropic stimulation","volume":"70","author":"Wang","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2014-8564_bib0145","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1677\/joe.0.1580247","article-title":"Premature elevation in serum insulin-like growth factor-I advances first ovulation in rhesus monkeys","volume":"158","author":"Wilson","year":"1998","journal-title":"J. Endocrinol."},{"key":"10.3168\/jds.2014-8564_bib0150","doi-asserted-by":"crossref","first-page":"761","DOI":"10.2527\/jas1965.243761x","article-title":"Prepuberal behavior and puberal characteristics of beef bulls on high nutrient allowance","volume":"24","author":"Wolf","year":"1965","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2014-8564_bib0155","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1439-0531.1990.tb00681.x","article-title":"The postnatal development of the bovine Leydig cell population","volume":"25","author":"Wrobel","year":"1990","journal-title":"Reprod. Domest. Anim."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214008431?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030214008431?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214008431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:27:24Z","timestamp":1731101244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030214008431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0022030214008431"],"URL":"https:\/\/doi.org\/10.3168\/jds.2014-8564","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}