{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:07:12Z","timestamp":1788433632198,"version":"build-2803163510"},"reference-count":41,"publisher":"American Dairy Science Association","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":1014,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"the Southeast Milk Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.3168\/jds.2015-10595","type":"journal-article","created":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:20:13Z","timestamp":1454545213000},"page":"3031-3040","source":"Crossref","is-referenced-by-count":40,"title":["Associations between pregnancy-associated glycoproteins and pregnancy outcomes, milk yield, parity, and clinical diseases in high-producing dairy cows"],"prefix":"10.3168","volume":"99","author":[{"given":"P.M.","family":"Mercadante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.S.","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Risco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.D.","family":"Ealy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2015-10595_bib0005","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.theriogenology.2007.03.010","article-title":"Influence of progesterone concentrations on secretory functions of trophoblast and pituitary during the first trimester of pregnancy in dairy cattle","volume":"67","author":"Ayad","year":"2007","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0010","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.theriogenology.2007.10.012","article-title":"Factors affecting plasma progesterone in the early fetal period in high producing dairy cows","volume":"69","author":"Bech-Sabat","year":"2008","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0015","doi-asserted-by":"crossref","first-page":"26","DOI":"10.15232\/S1080-7446(15)31480-7","article-title":"Cost of reproductive and conditions in cattle","volume":"18","author":"Bellows","year":"2002","journal-title":"Prof. Anim. Sci."},{"key":"10.3168\/jds.2015-10595_bib0020","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.theriogenology.2006.01.061","article-title":"Ultrasound fetal measurements and pregnancy associated glycoprotein secretion in early pregnancy in cattle recipients carrying somatic clones","volume":"66","author":"Chavatte-Palmer","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0025","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.2527\/1995.7392662x","article-title":"Effect of pregnancy-specific protein B on luteal cell progesterone, prostaglandin, and oxytocin production during two stages of the bovine estrous cycle","volume":"73","author":"Del Vecchio","year":"1995","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2015-10595_bib0030","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0090-6980(95)00108-5","article-title":"Prostaglandin F2 alpha, progesterone and oxytocin production by cultured bovine luteal cells treated with prostaglandin E2 and pregnancy-specific protein B","volume":"50","author":"Del Vecchio","year":"1995","journal-title":"Prostaglandins"},{"key":"10.3168\/jds.2015-10595_bib0035","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1530\/jrf.0.1070131","article-title":"Bovine luteal cell production in vitro of prostaglandin E2, oxytocin and progesterone in response to pregnancy-specific protein B and prostaglandin F2 alpha","volume":"107","author":"Del Vecchio","year":"1996","journal-title":"J. Reprod. Fertil."},{"key":"10.3168\/jds.2015-10595_bib0040","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","author":"Ferguson","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0045","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1439-0531.2006.00834.x","article-title":"Early detection of pregnancy and embryonic loss in dairy cattle by ELISA tests","volume":"42","author":"Gabor","year":"2007","journal-title":"Reprod. Domest. Anim."},{"issue":"Suppl. 9","key":"10.3168\/jds.2015-10595_bib0050","first-page":"55","article-title":"Concentration of bovine pregnancy associated glycoprotein in plasma and milk: Its application for pregnancy diagnosis in cows","volume":"59","author":"Gajewski","year":"2008","journal-title":"J. Physiol. Pharmacol."},{"key":"10.3168\/jds.2015-10595_bib0055","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/j.theriogenology.2004.07.011","article-title":"The establishment of an ELISA for the detection of pregnancy-associated glycoproteins (PAG) in the serum of pregnant cows and heifers","volume":"63","author":"Green","year":"2005","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0060","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1095\/biolreprod62.6.1624","article-title":"Pregnancy-associated bovine and ovine glycoproteins exhibit spatially and temporally distinct expression patterns during pregnancy","volume":"62","author":"Green","year":"2000","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2015-10595_bib0065","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1530\/ror.0.0030062","article-title":"Pepsin-related molecules secreted by trophoblast","volume":"3","author":"Green","year":"1998","journal-title":"Rev. Reprod."},{"key":"10.3168\/jds.2015-10595_bib0070","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1095\/biolreprod66.1.6","article-title":"Frequency and occurrence of late-gestation losses from cattle cloned embryos","volume":"66","author":"Heyman","year":"2002","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2015-10595_bib0075","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0093-691X(01)00644-6","article-title":"Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants","volume":"56","author":"Humblot","year":"2001","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0080","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0093-691X(88)90175-6","article-title":"Diagnosis of pregnancy by radioimmunoassay of a pregnancy-specific protein in the plasma of dairy cows","volume":"30","author":"Humblot","year":"1988","journal-title":"Theriogenology"},{"issue":"E-Suppl","key":"10.3168\/jds.2015-10595_bib0085","doi-asserted-by":"crossref","first-page":"E24","DOI":"10.2527\/2004.8213_supplE24x","article-title":"Preovulatory, postovulatory, and postmaternal recognition effects of concentrations of progesterone on embryonic survival in the cow","volume":"82","author":"Inskeep","year":"2004","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2015-10595_bib0090","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.cvfa.2005.02.002","article-title":"Embryonic death in cattle","volume":"21","author":"Inskeep","year":"2005","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.3168\/jds.2015-10595_bib0095","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1262\/jrd.2013-033","article-title":"Relationship of progesterone, bovine pregnancy-associated glycoprotein-1 and nitric oxide with late embryonic and early fetal mortalities in dairy cows","volume":"60","author":"Karen","year":"2014","journal-title":"J. Reprod. Dev."},{"key":"10.3168\/jds.2015-10595_bib0100","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.domaniend.2005.12.007","article-title":"Milk production correlates negatively with plasma levels of pregnancy-associated glycoprotein (PAG) during the early fetal period in high producing dairy cows with live fetuses","volume":"32","author":"Lopez-Gatius","year":"2007","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.3168\/jds.2015-10595_bib0105","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.theriogenology.2007.02.004","article-title":"Plasma concentrations of pregnancy-associated glycoprotein-1 (PAG-1) in high producing dairy cows suffering early fetal loss during the warm season","volume":"67","author":"Lopez-Gatius","year":"2007","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-10595_bib0110","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.3168\/jds.S0022-0302(01)70158-0","article-title":"Reproductive loss in high-producing dairy cattle: Where will it end?","volume":"84","author":"Lucy","year":"2001","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0115","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1530\/rep.0.1210175","article-title":"Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows","volume":"121","author":"Mann","year":"2001","journal-title":"Reproduction"},{"key":"10.3168\/jds.2015-10595_bib0120","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.3168\/jds.2011-4498","article-title":"Relationship between pregnancy per artificial insemination and early luteal concentrations of progesterone and establishment of repeatability estimates for these traits in Holstein-Friesian heifers","volume":"95","author":"Parr","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0125","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.2527\/jas.2013-6348","article-title":"Circulating bovine pregnancy associated glycoproteins are associated with late embryonic\/fetal survival but not ovulatory follicle size in suckled beef cows","volume":"91","author":"Pohler","year":"2013","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2015-10595_bib0130","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3168\/jds.S0022-0302(97)75937-X","article-title":"Pregnancy rates per artificial insemination for cows and heifers inseminated at a synchronized ovulation or synchronized estrus","volume":"80","author":"Pursley","year":"1997","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0135","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1095\/biolreprod.113.114694","article-title":"Low doses of bovine somatotropin enhance conceptus development and fertility in lactating dairy cows","volume":"90","author":"Ribeiro","year":"2014","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2015-10595_bib0140","doi-asserted-by":"crossref","first-page":"5682","DOI":"10.3168\/jds.2012-6335","article-title":"Prevalence of periparturient diseases and effects on fertility of seasonally calving grazing dairy cows supplemented with concentrates","volume":"96","author":"Ribeiro","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0145","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.3168\/jds.S0022-0302(02)74370-1","article-title":"High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17beta in dairy cattle","volume":"85","author":"Sangsritavong","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0150","first-page":"387","article-title":"Applying nutrition and physiology to improve reproduction in dairy cattle","volume":"67","author":"Santos","year":"2010","journal-title":"Soc. Reprod. Fertil. Suppl."},{"key":"10.3168\/jds.2015-10595_bib0155","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.anireprosci.2004.04.015","article-title":"The effect of embryonic death rates in cattle on the efficacy of estrus synchronization programs","volume":"82\u201383","author":"Santos","year":"2004","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2015-10595_bib0160","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.3168\/jds.S0022-0302(02)74367-1","article-title":"Fertilization and early embryonic development in heifers and lactating cows in summer and lactating and dry cows in winter","volume":"85","author":"Sartori","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0165","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1095\/biolreprod35.4.936","article-title":"Detection of pregnancy by radioimmunoassay of a novel pregnancy-specific protein in serum of cows and a profile of serum concentrations during gestation","volume":"35","author":"Sasser","year":"1986","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2015-10595_bib0170","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0090-6980(98)00063-X","article-title":"Effects of elevated concentrations of prostaglandin F2 alpha on pregnancy rates in progestogen supplemented cattle","volume":"56","author":"Seals","year":"1998","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.3168\/jds.2015-10595_bib0175","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/1471-2164-10-185","article-title":"Characterization of the bovine pregnancy-associated glycoprotein gene family\u2013analysis of gene sequences, regulatory regions within the promoter and expression of selected genes","volume":"10","author":"Telugu","year":"2009","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2015-10595_bib0180","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.3168\/jds.2009-2941","article-title":"Effects of resynchronization programs on pregnancy per artificial insemination, progesterone, and pregnancy-associated glycoproteins in plasma of lactating dairy cows","volume":"93","author":"Thompson","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0185","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3168\/jds.2010-3462","article-title":"Effects of postbreeding gonadotropin treatments on conception rates of lactating dairy cows subjected to timed artificial insemination or embryo transfer in a tropical environment","volume":"94","author":"Vasconcelos","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0190","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.prostaglandins.2007.08.002","volume":"84","author":"Weems","year":"2007","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.3168\/jds.2015-10595_bib0195","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0090-6980(98)00003-3","article-title":"Effect of luteinizing hormone (LH), PGE2, 8-EPI-PGE1, 8-EPI-PGE2, trichosanthin, and pregnancy specific protein B (PSPB) on secretion of progesterone in vitro by corpora lutea (CL) from nonpregnant and pregnant cows","volume":"55","author":"Weems","year":"1998","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.3168\/jds.2015-10595_bib0200","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.3168\/jds.S0022-0302(98)75788-1","article-title":"Effects of controlled heat stress on ovarian function of dairy cattle. 1. Lactating cows","volume":"81","author":"Wilson","year":"1998","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-10595_bib0205","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.placenta.2004.10.014","article-title":"Light and electron microscope immunocytochemical studies of the distribution of pregnancy associated glycoproteins (PAG) throughout pregnancy in the cow: Possible functional implications","volume":"26","author":"Wooding","year":"2005","journal-title":"Placenta"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030216001302?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030216001302?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030216001302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:43:46Z","timestamp":1731102226000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030216001302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S0022030216001302"],"URL":"https:\/\/doi.org\/10.3168\/jds.2015-10595","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]}}}