{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T18:43:55Z","timestamp":1787337835342,"version":"build-2736575974"},"reference-count":56,"publisher":"American Dairy Science Association","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T00:00:00Z","timestamp":1547596800000},"content-version":"vor","delay-in-days":1080,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100012752","name":"Elanco Animal Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012752","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.3168\/jds.2015-9572","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T01:57:27Z","timestamp":1450490247000},"page":"1351-1363","source":"Crossref","is-referenced-by-count":10,"title":["Effects of monensin and starch level in early lactation diets on indices of immune function in dairy cows"],"prefix":"10.3168","volume":"99","author":[{"given":"T.","family":"Yasui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.M.","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.M.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.O.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.B.","family":"Felippe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.D.","family":"Mechor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.R.","family":"Overton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2015-9572_bib0005","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1677\/joe.1.06438","article-title":"Diabetes causes marked changes in function and metabolism of rat neutrophils","volume":"188","author":"Alba-Loureiro","year":"2006","journal-title":"J. Endocrinol."},{"key":"10.3168\/jds.2015-9572_bib0010","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0301-6226(02)00303-2","article-title":"The effects of low vs. high concentrate level in the diet on performance in cows milked two or three times daily in early lactation","volume":"81","author":"Andersen","year":"2003","journal-title":"Livest. Prod. Sci."},{"key":"10.3168\/jds.2015-9572_bib0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.vetimm.2005.02.012","article-title":"Gene expression signatures in neutrophils exposed to glucocorticoids: A new paradigm to help explain \u201cneutrophil dysfunction\u201d in parturient dairy cows","volume":"105","author":"Burton","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0020","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1051\/vetres:2003023","article-title":"Severity of E. coli mastitis is mainly determined by cow factors","volume":"34","author":"Burvenich","year":"2003","journal-title":"Vet. Res."},{"key":"10.3168\/jds.2015-9572_bib0025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0301-6226(03)00112-X","article-title":"Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows","volume":"83","author":"Butler","year":"2003","journal-title":"Livest. Prod. Sci."},{"key":"10.3168\/jds.2015-9572_bib0030","first-page":"L277","article-title":"Ozone reduces murine alveolar and peritoneal macrophage phagocytosis: The role of prostanoids","volume":"261","author":"Canning","year":"1991","journal-title":"Am. J. Physiol."},{"key":"10.3168\/jds.2015-9572_bib0035","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.3168\/jds.2012-6111","article-title":"Propionate induces the release of granules from bovine neutrophils","volume":"96","author":"Carretta","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0040","doi-asserted-by":"crossref","first-page":"762","DOI":"10.3168\/jds.2010-3439","article-title":"Cow-level and herd-level risk factors for subclinical endometritis in lactating Holstein cows","volume":"94","author":"Cheong","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0045","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.vetimm.2004.10.009","article-title":"Innate immune traits differ between Meishan and Large White pigs","volume":"104","author":"Clapperton","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0050","doi-asserted-by":"crossref","first-page":"C1124","DOI":"10.1152\/ajpcell.1997.273.4.C1124","article-title":"Glutamine utilization by rat neutrophils: Presence of phosphate-dependent glutaminase","volume":"273","author":"Curi","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.3168\/jds.2015-9572_bib0055","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1182\/blood-2007-12-077917","article-title":"The phagocytes: Neutrophils and monocytes","volume":"112","author":"Dale","year":"2008","journal-title":"Blood"},{"key":"10.3168\/jds.2015-9572_bib0060","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0165-2427(94)05302-9","article-title":"Study of immunological dysfunction in periparturient Holstein cattle selected for high and average milk production","volume":"44","author":"Detilleux","year":"1995","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0065","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3168\/jds.S0022-0302(02)74087-3","article-title":"Prepartum monensin for the reduction of energy associated disease in postpartum dairy cows","volume":"85","author":"Duffield","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0070","series-title":"Proc. North American Veterinary Conference, Orlando, FL. The North American Veterinary Conference","first-page":"24","article-title":"Analysis of monensin use in lactating dairy cows","author":"Duffield","year":"2010"},{"key":"10.3168\/jds.2015-9572_bib0075","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.3168\/jds.2007-0607","article-title":"A meta-analysis of the impact of monensin in lactating dairy cattle. Part 1. Metabolic effects","volume":"91","author":"Duffield","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0080","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.3168\/jds.2007-0801","article-title":"A meta-analysis of the impact of monensin in lactating dairy cattle. Part 3. Health and reproduction","volume":"91","author":"Duffield","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0085","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1023\/A:1014033016308","article-title":"Simultaneous flow cytometric analysis of phagocytosis and oxidative burst activity in equine leukocytes","volume":"26","author":"Flaminio","year":"2002","journal-title":"Vet. Res. Commun."},{"key":"10.3168\/jds.2015-9572_bib0090","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1017\/S1751731109991601","article-title":"Nutritional sub-fertility in the dairy cow: Towards improved reproductive management through a better biological understanding","volume":"4","author":"Friggens","year":"2010","journal-title":"Animal"},{"key":"10.3168\/jds.2015-9572_bib0095","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.3168\/jds.2009-2551","article-title":"Association between uterine disease and indicators of neutrophil and systemic energy status in lactating Holstein cows","volume":"93","author":"Galv\u00e3o","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0100","doi-asserted-by":"crossref","first-page":"4906","DOI":"10.3168\/jds.2008-1984","article-title":"Effect of prostaglandin F2alpha on subclinical endometritis and fertility in dairy cows","volume":"92","author":"Galv\u00e3o","year":"2009","journal-title":"J. Dairy Sci."},{"issue":"Suppl. 1","key":"10.3168\/jds.2015-9572_bib0105","first-page":"469","article-title":"The relationship between postpartum uterine bacterial infection (BI) and subclinical endometritis (SE)","volume":"90","author":"Gilbert","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0110","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.theriogenology.2005.04.022","article-title":"Prevalence of endometritis and its effects on reproductive performance of dairy cows","volume":"64","author":"Gilbert","year":"2005","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-9572_bib0115","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1007\/BF02072085","article-title":"Defective neutrophil and monocyte functions in glycogen-storage-disease type-Ib: A literature review","volume":"152","author":"Gitzelmann","year":"1993","journal-title":"Eur. J. Pediatr."},{"key":"10.3168\/jds.2015-9572_bib0120","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1530\/rep.0.1230419","article-title":"Effect of dietary-induced increases in circulating insulin concentrations during the early postpartum period on reproductive function in dairy cows","volume":"123","author":"Gong","year":"2002","journal-title":"Reproduction"},{"key":"10.3168\/jds.2015-9572_bib0125","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.vetimm.2006.03.022","article-title":"Neutrophil function and energy status in Holstein cows with uterine health disorders","volume":"113","author":"Hammon","year":"2006","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0130","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1172\/JCI110199","article-title":"Role of insulin in the intermediary metabolism of the activated thymic-derived lymphocyte","volume":"67","author":"Helderman","year":"1981","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2015-9572_bib0135","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0301-6226(03)00110-6","article-title":"On the relationship between lactational performance and health: Is it yield or metabolic imbalance that cause production diseases in dairy cattle? A position paper","volume":"83","author":"Ingvartsen","year":"2003","journal-title":"Livest. Prod. Sci."},{"key":"10.3168\/jds.2015-9572_bib0140","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.vetimm.2003.08.018","article-title":"Repeatability of flow cytometric and classical measurement of phagocytosis and respiratory burst in bovine polymorphonuclear leukocytes","volume":"97","author":"Kampen","year":"2004","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0145","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1439-0531.2007.00960.x","article-title":"Reduced fertility in high-yielding dairy cows: Are the oocyte and embryo in danger? Part I. The importance of negative energy balance and altered corpus luteum function to the reduction of oocyte and embryo quality in high-yielding dairy cows","volume":"43","author":"Leroy","year":"2008","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2015-9572_bib0150","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3168\/jds.S0022-0302(98)75612-7","article-title":"Alteration in immune responsiveness during the peripartum period and its ramification on dairy cow and calf health","volume":"81","author":"Mallard","year":"1998","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0155","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1365-2362.2007.01786.x","article-title":"Glucose transporter expression on the plasma membrane of resting and activated white blood cells","volume":"37","author":"Maratou","year":"2007","journal-title":"Eur. J. Clin. Invest."},{"key":"10.3168\/jds.2015-9572_bib0160","doi-asserted-by":"crossref","first-page":"3335","DOI":"10.3168\/jds.2014-8820","article-title":"Performance of early lactation dairy cows as affected by dietary starch and monensin supplementation","volume":"98","author":"McCarthy","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0165","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.3168\/jds.2014-8821","article-title":"Metabolism of early lactation dairy cows as affected by dietary starch and monensin supplementation","volume":"98","author":"McCarthy","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0170","doi-asserted-by":"crossref","first-page":"587","DOI":"10.3168\/jds.2007-0379","article-title":"Effects of milking frequency on phagocytosis and oxidative burst activity of phagocytes from primiparous and multiparous dairy cows during early lactation","volume":"91","author":"Moya","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0175","doi-asserted-by":"crossref","first-page":"C286","DOI":"10.1152\/ajpcell.00335.2011","article-title":"Strong glucose dependence of electron current in human monocytes","volume":"302","author":"Musset","year":"2012","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.3168\/jds.2015-9572_bib0180","first-page":"47","article-title":"Glycogen in leukocytes from bovine blood and milk","volume":"37","author":"Naidu","year":"1973","journal-title":"Can. J. Comp. Med."},{"key":"10.3168\/jds.2015-9572_bib0185","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1042\/bj2390121","article-title":"Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages","volume":"239","author":"Newsholme","year":"1986","journal-title":"Biochem. J."},{"key":"10.3168\/jds.2015-9572_bib0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cbf.644","article-title":"The importance of fuel metabolism to macrophage function","volume":"14","author":"Newsholme","year":"1996","journal-title":"Cell Biochem. Funct."},{"key":"10.3168\/jds.2015-9572_bib0195","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.3168\/jds.2011-4515","article-title":"Technical note: The risk ratio, an alternative to the odds ratio for estimating the association between multiple risk factors and a dichotomous outcome","volume":"95","author":"Ospina","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0200","doi-asserted-by":"crossref","first-page":"916","DOI":"10.3168\/jds.S0022-0302(03)73674-1","article-title":"Effects of transition diets varying in dietary energy density on lactation performance and ruminal parameters of dairy cows","volume":"86","author":"Rabelo","year":"2003","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0205","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1051\/vetres:2006007","article-title":"Innate immunity of the bovine mammary gland","volume":"37","author":"Rainard","year":"2006","journal-title":"Vet. Res."},{"key":"10.3168\/jds.2015-9572_bib0210","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1172\/JCI108959","article-title":"Differences in oxygen metabolism of phagocytosing monocytes and neutrophils","volume":"61","author":"Reiss","year":"1978","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2015-9572_bib0215","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.tvjl.2007.07.030","article-title":"Differential alterations in the ability of bovine neutrophils to generate extracellular and intracellular reactive oxygen species during the periparturient period","volume":"178","author":"Rinaldi","year":"2008","journal-title":"Vet. J."},{"key":"10.3168\/jds.2015-9572_bib0220","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1095\/biolreprod.109.077370","article-title":"Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle","volume":"81","author":"Sheldon","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2015-9572_bib0225","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2015-9572_bib0230","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0165-2427(95)05465-0","article-title":"Enhanced production of bovine tumor necrosis factor-alpha during the periparturient period","volume":"49","author":"Sordillo","year":"1995","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2015-9572_bib0235","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1172\/JCI107531","article-title":"Phagocytic and bactericidal properties of normal human monocytes","volume":"53","author":"Steigbigel","year":"1974","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2015-9572_bib0240","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1751-0813.1996.tb13789.x","article-title":"The effect of monensin on the chemotactic function of bovine neutrophils","volume":"74","author":"Stephenson","year":"1996","journal-title":"Aust. Vet. J."},{"key":"10.3168\/jds.2015-9572_bib0245","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.jhep.2010.11.034","article-title":"Evidence of neutrophil functional defect despite inflammation in stable cirrhosis","volume":"55","author":"Tritto","year":"2011","journal-title":"J. Hepatol."},{"key":"10.3168\/jds.2015-9572_bib0250","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF00439409","article-title":"Impaired monocyte function in glycogen storage disease type Ib","volume":"145","author":"Ueno","year":"1986","journal-title":"Eur. J. Pediatr."},{"key":"10.3168\/jds.2015-9572_bib0255","doi-asserted-by":"crossref","first-page":"3397","DOI":"10.3168\/jds.2006-837","article-title":"Effect of glucogenic vs. lipogenic diets on energy balance, blood metabolites, and reproduction in primiparous and multiparous dairy cows in early lactation","volume":"90","author":"Van Knegsel","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0260","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/0-306-46832-8_29","article-title":"Mammary gland immunology around parturition\u2014Influence of stress, nutrition and genetics","volume":"480","author":"Waller","year":"2000","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.3168\/jds.2015-9572_bib0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physiolgenomics.00064.2009","article-title":"Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows","volume":"39","author":"Wathes","year":"2009","journal-title":"Physiol. Genomics"},{"key":"10.3168\/jds.2015-9572_bib0270","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF00916406","article-title":"Granulocytes utilize different energy sources for movement and phagocytosis","volume":"6","author":"Weisdorf","year":"1982","journal-title":"Inflammation"},{"key":"10.3168\/jds.2015-9572_bib0275","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.3168\/jds.2013-7322","article-title":"Effects of chromium propionate supplementation during the periparturient period and early lactation on metabolism, performance, and cytological endometritis in dairy cows","volume":"97","author":"Yasui","year":"2014","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2015-9572_bib0280","doi-asserted-by":"crossref","first-page":"6400","DOI":"10.3168\/jds.2013-7796","article-title":"Associations of cytological endometritis with energy metabolism and inflammation during the periparturient period and early lactation in dairy cows","volume":"97","author":"Yasui","year":"2014","journal-title":"J. Dairy Sci."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030215009078?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030215009078?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030215009078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:41:48Z","timestamp":1731102108000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030215009078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["S0022030215009078"],"URL":"https:\/\/doi.org\/10.3168\/jds.2015-9572","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]}}}