{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:15:43Z","timestamp":1790072143192,"version":"4.0.1"},"reference-count":63,"publisher":"American Dairy Science Association","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T00:00:00Z","timestamp":1547078400000},"content-version":"vor","delay-in-days":588,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.3168\/jds.2016-12164","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T09:16:42Z","timestamp":1492766202000},"page":"4721-4730","source":"Crossref","is-referenced-by-count":85,"title":["Genome-wide mapping and estimation of inbreeding depression of semen quality traits in a cattle population"],"prefix":"10.3168","volume":"100","author":[{"given":"Maja","family":"Feren\u010dakovi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"S\u00f6lkner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Kap\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ino","family":"Curik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2016-12164_bib1","doi-asserted-by":"crossref","first-page":"baw093","DOI":"10.1093\/database\/baw093","article-title":"The Ensembl gene annotation system","volume":"2016","author":"Aken","year":"2016","journal-title":"Database (Oxford)"},{"key":"10.3168\/jds.2016-12164_bib2","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1021\/acs.jproteome.5b01080","article-title":"Testis-specific Y-centric protein-protein interaction network provides clues to the etiology of severe spermatogenic failure","volume":"15","author":"Ansari-Pour","year":"2016","journal-title":"J. Proteome Res."},{"key":"10.3168\/jds.2016-12164_bib3","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1469-1795.2007.00116.x","article-title":"Relationship of inbreeding with sperm quality and reproductive success in Mexican gray wolves","volume":"10","author":"Asa","year":"2007","journal-title":"Anim. Conserv."},{"key":"10.3168\/jds.2016-12164_bib4","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0093-691X(03)00005-0","article-title":"Semen parameters and level of microsatellite heterozygosity in Noriker draught horse stallions","volume":"60","author":"Aurich","year":"2003","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2016-12164_bib5","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0906079106","article-title":"Consanguinity, human evolution, and complex diseases","volume":"107","author":"Bittles","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.3168\/jds.2016-12164_bib6","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.3168\/jds.2012-6435","article-title":"Evaluation of inbreeding depression in Holstein cattle using whole-genome SNP markers and alternative measures of genomic inbreeding","volume":"96","author":"Bjelland","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2016-12164_bib7","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1128\/MCB.01072-10","article-title":"SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63","volume":"31","author":"Bornstein","year":"2011","journal-title":"Mol. Cell. Biol."},{"key":"10.3168\/jds.2016-12164_bib8","doi-asserted-by":"crossref","first-page":"e1003100","DOI":"10.1371\/journal.pgen.1003100","article-title":"Regions of homozygosity in the porcine genome: Consequence of demography and the recombination landscape","volume":"8","author":"Bosse","year":"2012","journal-title":"PLoS Genet."},{"key":"10.3168\/jds.2016-12164_bib9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.2517-6161.1964.tb00553.x","article-title":"An analysis of transformations","author":"Box","year":"1964","journal-title":"J. R. Stat. Soc. Ser. B (Methodological)"},{"key":"10.3168\/jds.2016-12164_bib10","series-title":"Model Selection and Multimodel Inference: A Practical Information-Theoretic Approach","author":"Burnham","year":"2007"},{"key":"10.3168\/jds.2016-12164_bib11","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1046\/j.1365-2540.2001.00901.x","article-title":"A simple correction for multiple comparisons in interval mapping genome scans","volume":"87","author":"Cheverud","year":"2001","journal-title":"Heredity (Edinb.)"},{"key":"10.3168\/jds.2016-12164_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.livsci.2014.05.034","article-title":"Inbreeding and runs of homozygosity: A possible solution to an old problem","volume":"166","author":"Curik","year":"2014","journal-title":"Livest. Sci."},{"key":"10.3168\/jds.2016-12164_bib13","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1086\/521314","article-title":"Homozygous mutation in SPATA16 is associated with male infertility in human globozoospermia","volume":"81","author":"Dam","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.3168\/jds.2016-12164_bib14","article-title":"Effect of inbreeding depression on bull sperm quality and field fertility","author":"Dorado","year":"2015","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2016-12164_bib15","article-title":"Runs of homozygosity reveal genomewide autozygosity in the Austrian Fleckvieh cattle","volume":"76","author":"Ferencakovic","year":"2011","journal-title":"Agric. Conspec. Sci."},{"key":"10.3168\/jds.2016-12164_bib16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1297-9686-45-42","article-title":"Estimating autozygosity from high-throughput information: Effect of SNP density and genotyping errors","volume":"45","author":"Feren\u010dakovi\u0107","year":"2013","journal-title":"Genet. Sel. Evol."},{"key":"10.3168\/jds.2016-12164_bib17","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1098\/rsbl.2008.0734","article-title":"Reduced heterozygosity impairs sperm quality in endangered mammals","volume":"5","author":"Fitzpatrick","year":"2009","journal-title":"Biol. Lett."},{"key":"10.3168\/jds.2016-12164_bib18","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.cub.2006.02.059","article-title":"Reduced heterozygosity depresses sperm quality in wild rabbits, Oryctolagus cuniculus","volume":"16","author":"Gage","year":"2006","journal-title":"Curr. Biol."},{"key":"10.3168\/jds.2016-12164_bib19","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/gepi.20310","article-title":"A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms","volume":"32","author":"Gao","year":"2008","journal-title":"Genet. Epidemiol."},{"key":"10.3168\/jds.2016-12164_bib20","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/hmg\/ddi493","article-title":"Extended tracts of homozygosity in outbred human populations","volume":"15","author":"Gibson","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.3168\/jds.2016-12164_bib21","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1439-0388.2005.00512.x","article-title":"A note on ENDOG: A computer program for analysing pedigree information","volume":"122","author":"Guti\u00e9rrez","year":"2005","journal-title":"J. Anim. Breed. Genet."},{"key":"10.3168\/jds.2016-12164_bib22","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1042\/bj3330005","article-title":"The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: Implications for the role of GPX5 in the male reproductive tract","volume":"333","author":"Hall","year":"1998","journal-title":"Biochem. J."},{"key":"10.3168\/jds.2016-12164_bib23","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.anireprosci.2014.01.012","article-title":"Genome-wide association study for poor sperm motility in Holstein-Friesian bulls","volume":"146","author":"Hering","year":"2014","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2016-12164_bib24","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm","year":"1979","journal-title":"Scand. J. Stat."},{"key":"10.3168\/jds.2016-12164_bib25","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1186\/s12864-015-2001-7","article-title":"Investigation of regions impacting inbreeding depression and their association with the additive genetic effect for United States and Australia Jersey dairy cattle","volume":"16","author":"Howard","year":"2015","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2016-12164_bib26","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/mp.2015.120","article-title":"Genome-wide autozygosity is associated with lower general cognitive ability","volume":"21","author":"Howrigan","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.3168\/jds.2016-12164_bib27","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1186\/1471-2164-12-460","article-title":"Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms","volume":"12","author":"Howrigan","year":"2011","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2016-12164_bib28","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.fertnstert.2011.11.002","article-title":"Should TSPYL1 mutation screening be included in routine diagnostics of male idiopathic infertility?","volume":"97","author":"Javaher","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.3168\/jds.2016-12164_bib29","doi-asserted-by":"crossref","first-page":"e1002656","DOI":"10.1371\/journal.pgen.1002656","article-title":"Runs of homozygosity implicate autozygosity as a schizophrenia risk factor","volume":"8","author":"Keller","year":"2012","journal-title":"PLoS Genet."},{"key":"10.3168\/jds.2016-12164_bib30","doi-asserted-by":"crossref","first-page":"e80813","DOI":"10.1371\/journal.pone.0080813","article-title":"Effect of artificial selection on runs of homozygosity in U.S. Holstein cattle","volume":"8","author":"Kim","year":"2013","journal-title":"PLoS One"},{"key":"10.3168\/jds.2016-12164_bib31","doi-asserted-by":"crossref","first-page":"e0129967","DOI":"10.1371\/journal.pone.0129967","article-title":"The relationship between runs of homozygosity and inbreeding in Jersey cattle under selection","volume":"10","author":"Kim","year":"2015","journal-title":"PLoS One"},{"key":"10.3168\/jds.2016-12164_bib32","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1079\/ASC41960121","article-title":"Inbreeding\u2013Lessons from animal breeding, evolutionary biology and conservation genetics","volume":"80","author":"Kristensen","year":"2005","journal-title":"Anim. Sci."},{"key":"10.3168\/jds.2016-12164_bib33","doi-asserted-by":"crossref","DOI":"10.1111\/age.12178","article-title":"Inbreeding depression in livestock species: Review and meta-analysis","volume":"45","author":"Leroy","year":"2014","journal-title":"Anim. Genet."},{"key":"10.3168\/jds.2016-12164_bib34","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1071\/RD01120","article-title":"The effects of inbreeding on testicular sperm concentration in Peromyscus polionotus","volume":"14","author":"Margulis","year":"2002","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2016-12164_bib35","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1111\/j.1439-0531.2010.01645.x","article-title":"Inbreeding depression on semen quality in Austrian dual-purpose Simmental bulls","volume":"46","author":"Maximini","year":"2011","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2016-12164_bib36","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.ajhg.2008.08.007","article-title":"Runs of homozygosity in European populations","volume":"83","author":"McQuillan","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"10.3168\/jds.2016-12164_bib37","doi-asserted-by":"crossref","first-page":"9376","DOI":"10.1074\/jbc.M111.314955","article-title":"NOX5 in human spermatozoa: Expression, function, and regulation","volume":"287","author":"Musset","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2016-12164_bib38","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1534\/genetics.105.049940","article-title":"Estimating relatedness between individuals in general populations with a focus on their use in conservation programs","volume":"173","author":"Oliehoek","year":"2006","journal-title":"Genetics"},{"key":"10.3168\/jds.2016-12164_bib39","doi-asserted-by":"crossref","first-page":"e20280","DOI":"10.1371\/journal.pone.0020280","article-title":"Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm","volume":"6","author":"Pacheco","year":"2011","journal-title":"PLoS One"},{"key":"10.3168\/jds.2016-12164_bib40","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.mam.2012.05.005","article-title":"The mitochondrial transporter family SLC25: Identification, properties and physiopathology","volume":"34","author":"Palmieri","year":"2013","journal-title":"Mol. Aspects Med."},{"key":"10.3168\/jds.2016-12164_bib41","doi-asserted-by":"crossref","first-page":"e1004044","DOI":"10.1371\/journal.pgen.1004044","article-title":"A nonsense mutation in TMEM95 encoding a nondescript transmembrane protein causes idiopathic male subfertility in cattle","volume":"10","author":"Pausch","year":"2014","journal-title":"PLoS Genet."},{"key":"10.3168\/jds.2016-12164_bib42","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12864-015-1483-7","article-title":"Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle","volume":"16","author":"Pausch","year":"2015","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2016-12164_bib43","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12711-014-0071-7","article-title":"Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle","volume":"46","author":"Pryce","year":"2014","journal-title":"Genet. Sel. Evol."},{"key":"10.3168\/jds.2016-12164_bib44","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.theriogenology.2006.03.020","article-title":"The impact and potential etiology of teratospermia in the domestic cat and its wild relatives","volume":"66","author":"Pukazhenthi","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2016-12164_bib45","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2156-13-70","article-title":"Runs of homozygosity and population history in cattle","volume":"13","author":"Purfield","year":"2012","journal-title":"BMC Genet."},{"key":"10.3168\/jds.2016-12164_bib46","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1095\/biolreprod.110.084798","article-title":"High levels of DNA fragmentation in spermatozoa are associated with inbreeding and poor sperm quality in endangered ungulates","volume":"83","author":"Ruiz-Lopez","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2016-12164_bib47","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1530\/REP-06-0120","article-title":"Characterization of NADPH oxidase 5 in equine testis and spermatozoa","volume":"134","author":"Sabeur","year":"2007","journal-title":"Reproduction"},{"key":"10.3168\/jds.2016-12164_bib48","unstructured":"Sargolzaei, M., H. Iwaisaki, and J. J. Colleau. 2006. CFC: A tool for monitoring genetic diversity. (CD-ROM Communication, pages 27\u201328) in Proc. 8th World Congr. Genet. Appl. Livest. Prod."},{"key":"10.3168\/jds.2016-12164_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12711-014-0081-5","article-title":"Detecting inbreeding depression for reproductive traits in Iberian pigs using genome-wide data","volume":"47","author":"Saura","year":"2015","journal-title":"Genet. Sel. Evol."},{"key":"10.3168\/jds.2016-12164_bib50","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1074\/jbc.273.6.3509","article-title":"Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes","volume":"273","author":"Schreiber","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2016-12164_bib51","first-page":"923","article-title":"Assessment of inbreeding depression in big cats: Testosterone levels and semen analysis","volume":"75","author":"Shivaji","year":"1998","journal-title":"Curr. Sci."},{"key":"10.3168\/jds.2016-12164_bib52","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jprot.2013.02.027","article-title":"Proteins associated with critical sperm functions and sperm head shape are differentially expressed in morphologically abnormal bovine sperm induced by scrotal insulation","volume":"82","author":"Shojaei Saadi","year":"2013","journal-title":"J. Proteomics"},{"key":"10.3168\/jds.2016-12164_bib53","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1039\/c3mb25494a","article-title":"Unravelling the bull fertility proteome","volume":"9","author":"Soggiu","year":"2013","journal-title":"Mol. Biosyst."},{"key":"10.3168\/jds.2016-12164_bib54","series-title":"61st Annual Meeting of the European Association of Animal Production, Heraklion","first-page":"306","article-title":"Genomic metrics of individual autozygosity, applied to a cattle population","author":"S\u00f6lkner","year":"2010"},{"key":"10.3168\/jds.2016-12164_bib55","doi-asserted-by":"crossref","first-page":"e54872","DOI":"10.1371\/journal.pone.0054872","article-title":"Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle","volume":"8","author":"Sonstegard","year":"2013","journal-title":"PLoS One"},{"key":"10.3168\/jds.2016-12164_bib56","doi-asserted-by":"crossref","first-page":"5369","DOI":"10.1093\/nar\/gkf696","article-title":"Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes","volume":"30","author":"Uechi","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"10.3168\/jds.2016-12164_bib57","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.theriogenology.2005.08.001","article-title":"Possible negative effects of inbreeding on semen quality in Shetland pony stallions","volume":"65","author":"van Eldik","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2016-12164_bib58","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.3168\/jds.2007-0980","article-title":"Efficient methods to compute genomic predictions","volume":"91","author":"VanRaden","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2016-12164_bib59","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.theriogenology.2014.06.002","article-title":"Sperm ubiquitination in epididymal feline semen","volume":"82","author":"Vernocchi","year":"2014","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2016-12164_bib60","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1002\/dvdy.21694","article-title":"Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development","volume":"237","author":"Wang","year":"2008","journal-title":"Dev. Dyn."},{"key":"10.3168\/jds.2016-12164_bib61","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0093-691X(82)90026-7","article-title":"Influence of inbreeding on reproductive performance, ejaculate quality and testicular volume in the dog","volume":"17","author":"Wildt","year":"1982","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2016-12164_bib62","doi-asserted-by":"crossref","first-page":"272","DOI":"10.2164\/jandrol.106.000604","article-title":"Equatorial segment protein (ESP) is a human alloantigen involved in sperm-egg binding and fusion","volume":"29","author":"Wolkowicz","year":"2008","journal-title":"J. Androl."},{"key":"10.3168\/jds.2016-12164_bib63","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1745-7262.2005.00041.x","article-title":"Identification of a novel testis-specific gene and its potential roles in testis development\/spermatogenesis","volume":"7","author":"Yin","year":"2005","journal-title":"Asian J. Androl."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030217303235?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030217303235?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030217303235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:57:47Z","timestamp":1731103067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030217303235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":63,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0022030217303235"],"URL":"https:\/\/doi.org\/10.3168\/jds.2016-12164","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]}}}