{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T21:17:25Z","timestamp":1785273445948,"version":"3.55.0"},"reference-count":41,"publisher":"American Dairy Science Association","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.3168\/jds.2018-14653","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T23:36:33Z","timestamp":1533857793000},"page":"9575-9590","source":"Crossref","is-referenced-by-count":19,"title":["Dose frequency of prostaglandin F2\u03b1 administration to dairy cows exposed to presynchronization and either 5- or 7-day Ovsynch program durations: Ovulatory and luteolytic risks"],"prefix":"10.3168","volume":"101","author":[{"given":"J.S.","family":"Stevenson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Sauls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.G.D.","family":"Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.E.","family":"Voelz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2018-14653_bib1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.theriogenology.2014.10.034","article-title":"Low-dose natural prostaglandin F2\u03b1 (dinoprost) at timed insemination improves conception rate in dairy cattle","volume":"83","author":"Ambrose","year":"2015","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2018-14653_bib2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.theriogenology.2012.10.001","article-title":"Double-Ovsynch in high-producing dairy cows: Effects on progesterone concentrations and ovulation to GnRH treatments","volume":"79","author":"Ayres","year":"2013","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2018-14653_bib3","doi-asserted-by":"crossref","first-page":"5739","DOI":"10.3168\/jds.2009-2226","article-title":"Genetic parameters for anovulation and pregnancy loss in dairy cattle","volume":"92","author":"Bamber","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib4","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.3168\/jds.2017-13628","article-title":"Effect of dose and timing of prostaglandin F2\u03b1 treatments during a Resynch protocol on luteal regression and fertility to timed artificial insemination in lactating Holstein cows","volume":"101","author":"Barletta","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib5","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.3168\/jds.2016-11956","article-title":"Evaluation of prostaglandin F2\u03b1 versus prostaglandin F2\u03b1 plus gonadotropin-releasing hormone as Presynch methods preceding an Ovsynch in lactating dairy cows: A meta-analysis","volume":"100","author":"Borchardt","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib6","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.theriogenology.2007.12.011","article-title":"Decreasing the interval between GnRH and PGF2\u03b1 from 7 to 5 days and lengthening proestrus increases timed-AI pregnancy rates in beef cows","volume":"69","author":"Bridges","year":"2008","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2018-14653_bib7","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.3168\/jds.S0022-0302(06)72522-X","article-title":"Survey of management practices on reproductive performance of dairy cattle on large US commercial farms","volume":"89","author":"Caraviello","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib8","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.3168\/jds.2013-7809","article-title":"Relationships between fertility and postpartum changes in body condition and body weight in lactating dairy cows","volume":"97","author":"Carvalho","year":"2014","journal-title":"J. Dairy Sci."},{"issue":"Suppl. 1","key":"10.3168\/jds.2018-14653_bib9","first-page":"86","article-title":"Effect of artificial insemination (AI) protocol on fertilization and embryo quality in high-producing dairy cows","volume":"88","author":"Cerri","year":"2005","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib10","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/rda.12518","article-title":"Effect of initial GnRH and duration of progesterone insert treatment on the fertility of lactating dairy cows","volume":"50","author":"Colazo","year":"2015","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2018-14653_bib11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1095\/biolreprod50.2.233","article-title":"Current status of the hypothesis that mammalian ovulation is comparable to an inflammatory reaction","volume":"50","author":"Espey","year":"1994","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2018-14653_bib12","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","author":"Ferguson","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib13","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.3168\/jds.2007-0173","article-title":"Breed and parity effects on energy balance profiles through lactation: Evidence of genetically driven body energy change","volume":"90","author":"Friggens","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib14","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.3168\/jds.2007-0182","article-title":"Reducing the interval from presynchronization to initiation of timed artificial insemination improves fertility in dairy cows","volume":"90","author":"Galv\u00e3o","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib15","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.3168\/jds.S0022-0302(03)73921-6","article-title":"Follicular size and response to Ovsynch versus detection of estrus in anovular and ovular lactating dairy cows","volume":"86","author":"G\u00fcmen","year":"2003","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib16","doi-asserted-by":"crossref","first-page":"7003","DOI":"10.3168\/jds.2011-5260","article-title":"Presynchronization with Double-Ovsynch improves fertility at first postpartum artificial insemination in lactating dairy cows","volume":"95","author":"Herlihy","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib17","doi-asserted-by":"crossref","first-page":"3722","DOI":"10.2527\/jas.2016-0582","article-title":"Gonadotropin-releasing hormone increased pregnancy risk in suckled beef cows not detected in estrus and subjected to a split-time artificial insemination program","volume":"94","author":"Hill","year":"2016","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2018-14653_bib18","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1530\/jrf.0.0900245","article-title":"Prostaglandin F-2 alpha causes regression of an hCG-induced corpus luteum before day 5 of its lifespan in cattle","volume":"90","author":"Howard","year":"1990","journal-title":"J. Reprod. Fertil."},{"key":"10.3168\/jds.2018-14653_bib19","doi-asserted-by":"crossref","first-page":"5107","DOI":"10.3168\/jds.2016-11628","article-title":"The effect of presynchronization with prostaglandin F2\u03b1 and gonadotropin-releasing hormone simultaneously, 7 d before Ovsynch, compared with Presynch-10\/Ovsynch on luteal function and first-service pregnancies per artificial insemination","volume":"100","author":"Martins","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib20","series-title":"Encyclopedia of Reproduction","first-page":"1083","article-title":"Luteolysis","volume":"Vol. 2","author":"McCracken","year":"1998"},{"key":"10.3168\/jds.2018-14653_bib21","series-title":"Proc. 10th Int. Cong. Anim. Reprod. AI","first-page":"336","article-title":"Influence of day of estrous cycle on response to PGF2 alpha products: Implication for AI programs for dairy cattle","author":"Momont","year":"1984"},{"key":"10.3168\/jds.2018-14653_bib22","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1071\/RD12319","article-title":"Effects of systemic progesterone during the early luteal phase on the availabilities of amino acids and glucose in the bovine uterine lumen","volume":"26","author":"Mullen","year":"2014","journal-title":"Reprod. Fertil. Dev."},{"key":"10.3168\/jds.2018-14653_bib23","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.theriogenology.2013.10.009","article-title":"Lack of complete regression of the Day 5 corpus luteum after one or two doses of PGF2\u03b1 in nonlactating Holstein cows","volume":"81","author":"Nascimento","year":"2014","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2018-14653_bib24","series-title":"US Dept. Commerce, Natl. Weather Serv. Central Reg., Reg. Operations Manual Lett","first-page":"31","article-title":"Livestock hot weather stress","author":"NOAA (National Oceanic and Atmospheric Administration)","year":"1976"},{"key":"10.3168\/jds.2018-14653_bib25","series-title":"Nutrient Requirements of Dairy Cattle","author":"NRC (National Research Council)","year":"2001"},{"key":"10.3168\/jds.2018-14653_bib26","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.3168\/jds.S0022-0302(98)75790-X","article-title":"Effect of time of artificial insemination on pregnancy rates, calving rates, pregnancy loss, and gender ratio after synchronization of ovulation in lactating dairy cows","volume":"81","author":"Pursley","year":"1998","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib27","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.theriogenology.2012.01.012","article-title":"Fertility in dairy cows following presynchronization and administering twice the luteolytic dose of prostaglandin F2\u03b1 as one or two injections in the 5-day timed artificial insemination protocol","volume":"78","author":"Ribeiro","year":"2012","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2018-14653_bib28","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.3168\/jds.2011-4921","article-title":"Effects of presynchronization and length of proestrus on fertility of grazing dairy cows subjected to a 5-day timed artificial insemination protocol","volume":"95","author":"Ribeiro","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib29","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.3168\/jds.2009-2870","article-title":"Effect of reducing the period of follicle dominance in a timed artificial insemination protocol on reproduction of dairy cows","volume":"93","author":"Santos","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.anireprosci.2008.01.014","article-title":"Risk factors for resumption of postpartum estrous cycles and embryonic survival in lactating dairy cows","volume":"110","author":"Santos","year":"2009","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2018-14653_bib31","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.3168\/jds.2015-10557","article-title":"Adding a second prostaglandin F2\u03b1 treatment to but not reducing the duration of a PRID-Synch protocol increases fertility after resynchronization of ovulation in lactating Holstein cows","volume":"99","author":"Santos","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib32","doi-asserted-by":"crossref","first-page":"10077","DOI":"10.3168\/jds.2016-11247","article-title":"Physiological predictors of ovulation and pregnancy risk in a fixed-time artificial insemination program","volume":"99","author":"Stevenson","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib33","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.3168\/jds.2015-10091","article-title":"Feedback effects of estradiol and progesterone on ovulation and fertility after gonadotropin-releasing hormone-induced release of luteinizing hormone","volume":"99","author":"Stevenson","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib34","doi-asserted-by":"crossref","first-page":"5769","DOI":"10.3168\/jds.2013-6845","article-title":"Change in dose delivery of prostaglandin F2\u03b1 in a 5-day timed artificial insemination program in lactating dairy cows","volume":"96","author":"Stevenson","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib35","doi-asserted-by":"crossref","first-page":"7586","DOI":"10.3168\/jds.2014-8312","article-title":"Pregnancy outcomes after change in dose delivery of prostaglandin F2\u03b1 in a 5-day timed artificial insemination program in lactating dairy cows","volume":"97","author":"Stevenson","year":"2014","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib36","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.3168\/jds.2011-4767","article-title":"Prostaglandin F2\u03b1 and gonadotropin-releasing hormone GnRH administration improve progesterone status, luteal number, and proportion of ovular and anovular dairy cows with corpora lutea before a timed AI program","volume":"95","author":"Stevenson","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib37","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.3168\/jds.2007-0856","article-title":"Detection of anovulation by heatmount detectors and transrectal ultrasonography before treatment with progesterone in a timed insemination protocol","volume":"91","author":"Stevenson","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib38","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.tvjl.2004.11.014","article-title":"Prostaglandins and reproduction in female farm animals","volume":"171","author":"Weems","year":"2006","journal-title":"Vet. J."},{"key":"10.3168\/jds.2018-14653_bib39","doi-asserted-by":"crossref","first-page":"8644","DOI":"10.3168\/jds.2015-9353","article-title":"Effect of a second treatment with prostaglandin F2\u03b1 during the Ovsynch protocol on luteolysis and pregnancy in dairy cows","volume":"98","author":"Wiltbank","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2018-14653_bib40","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1095\/biolreprod52.1.74","article-title":"Prostaglandin F2 alpha receptors in the early bovine corpus luteum","volume":"52","author":"Wiltbank","year":"1995","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2018-14653_bib41","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.3168\/jds.2016-11750","article-title":"Consistent magnitude of postpartum body weight loss within cows across lactations and the relation to reproductive performance","volume":"100","author":"Zachut","year":"2017","journal-title":"J. Dairy Sci."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030218307252?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030218307252?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030218307252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:28:51Z","timestamp":1731101331000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030218307252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0022030218307252"],"URL":"https:\/\/doi.org\/10.3168\/jds.2018-14653","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}