{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:25:35Z","timestamp":1790087135975,"version":"4.0.1"},"reference-count":54,"publisher":"American Dairy Science Association","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.3168\/jds.2020-18523","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T21:29:03Z","timestamp":1596230943000},"page":"9318-9331","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of xylazine administration before laparoscopic abomasopexy to correct left displaced abomasum on markers of stress in dairy cows"],"prefix":"10.3168","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9640-9190","authenticated-orcid":false,"given":"T.S.","family":"Tschoner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6928-4089","authenticated-orcid":false,"given":"Y.","family":"Zablotski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0928-5933","authenticated-orcid":false,"given":"G.","family":"Knubben-Schweizer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9374-9122","authenticated-orcid":false,"given":"M.","family":"Feist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2020-18523_bib1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.cvfa.2012.11.006","article-title":"Prevention and management of surgical pain in cattle","volume":"29","author":"Anderson","year":"2013","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.3168\/jds.2020-18523_bib2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.cvfa.2005.07.002","article-title":"Pain management in cattle","volume":"21","author":"Anderson","year":"2005","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.3168\/jds.2020-18523_bib3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.17236\/sat00025","article-title":"Evaluation of eating and rumination behaviour using a noseband pressure sensor in cows after right-flank laparotomy for correction of left displaced abomasum","volume":"157","author":"Braun","year":"2015","journal-title":"Schweiz. Arch. Tierheilkd."},{"key":"10.3168\/jds.2020-18523_bib4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.17236\/sat00104","article-title":"Eating and rumination behaviour in cows with traumatic reticuloperitonitis","volume":"159","author":"Braun","year":"2017","journal-title":"Schweiz. Arch. Tierheilkd."},{"key":"10.3168\/jds.2020-18523_bib5","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.rvsc.2015.05.001","article-title":"Eating and rumination activity in 10 cows over 10 days","volume":"101","author":"Braun","year":"2015","journal-title":"Res. Vet. Sci."},{"key":"10.3168\/jds.2020-18523_bib6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/s12917-015-0549-8","article-title":"Evaluation of eating and rumination behaviour in 300 cows of three different breeds using a noseband pressure sensor","volume":"11","author":"Braun","year":"2015","journal-title":"BMC Vet. Res."},{"key":"10.3168\/jds.2020-18523_bib7","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.physbeh.2006.11.015","article-title":"Cortisol levels and anxiety-related behaviors in cattle","volume":"90","author":"Bristow","year":"2007","journal-title":"Physiol. Behav."},{"key":"10.3168\/jds.2020-18523_bib8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.applanim.2011.10.016","article-title":"A review of pain assessment techniques and pharmacological approaches to pain relief after bovine castration: Practical implications for cattle production within the United States","volume":"135","author":"Coetzee","year":"2011","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.3168\/jds.2020-18523_bib9","doi-asserted-by":"crossref","first-page":"751","DOI":"10.2460\/ajvr.69.6.751","article-title":"Plasma concentrations of substance P and cortisol in beef calves after castration or simulated castration","volume":"69","author":"Coetzee","year":"2008","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2020-18523_bib10","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.2460\/ajvr.1996.57.07.1031","article-title":"Ketoprofen concentrations in plasma and milk after intravenous administration in dairy cattle","volume":"57","author":"De Graves","year":"1996","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2020-18523_bib11","series-title":"Innere Medizin und Chirurgie des Rindes","first-page":"357","article-title":"Krankheiten der Verdauungsorgane und der Bauchwand","author":"Dirksen","year":"2006"},{"key":"10.3168\/jds.2020-18523_bib12","series-title":"Lehrbuch der Pharmakologie und Toxikologie f\u00fcr die Veterin\u00e4rmedizin","first-page":"87","article-title":"Pharmakologie des zentralen Nervensystems (ZNS)","author":"Ebert","year":"2002"},{"key":"10.3168\/jds.2020-18523_bib13","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.3168\/jds.S0022-0302(00)75084-3","article-title":"Reducing pain after dehorning in dairy calves","volume":"83","author":"Faulkner","year":"2000","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib14","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1055\/s-0038-1623861","article-title":"Claw surgery in cattle: The benefit of perioperative analgesics","volume":"36","author":"Feist","year":"2008","journal-title":"Tierarztl. Prax."},{"key":"10.3168\/jds.2020-18523_bib15","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13620-018-0132-2","article-title":"Association between left-displaced abomasum corrected with 2-step laparoscopic abomasopexy and milk production in a commercial dairy farm in Italy","volume":"71","author":"Fiore","year":"2018","journal-title":"Ir. Vet. J."},{"key":"10.3168\/jds.2020-18523_bib16","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3168\/jds.2011-4350","article-title":"Sickness behavior in dairy cows during Escherichia coli mastitis","volume":"95","author":"Fogsgaard","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.applanim.2015.08.023","article-title":"Pain evaluation in dairy cattle","volume":"171","author":"Gleerup","year":"2015","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.3168\/jds.2020-18523_bib18","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.3168\/jds.2007-0530","article-title":"Changes in feeding behavior as possible indicators for the automatic monitoring of health disorders in dairy cows","volume":"91","author":"Gonz\u00e1lez","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib19","series-title":"Schmerzmanagement bei Klein- und Heimtieren","first-page":"11","article-title":"Wie entsteht Schmerz?","author":"Henke","year":"2001"},{"key":"10.3168\/jds.2020-18523_bib20","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.2460\/ajvr.2002.63.1695","article-title":"Cardiopulmonary effects of xylazine and acepromazine in pregnant cows in late gestation","volume":"63","author":"Hodgson","year":"2002","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2020-18523_bib21","series-title":"Medizinische Biochemie systematisch","first-page":"623","article-title":"Hormone und Stoffwechsel","author":"Hofmann","year":"2006"},{"key":"10.3168\/jds.2020-18523_bib22","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1046\/j.0954-6820.2000.00773.x","article-title":"Substance P: A pioneer amongst neuropeptides","volume":"249","author":"H\u00f6kfelt","year":"2001","journal-title":"J. Intern. Med."},{"key":"10.3168\/jds.2020-18523_bib23","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1210\/endo-109-3-825","article-title":"Xylazine-induced hyperglycemia in cattle: a possible involvement of a2-adrenergic receptors regulating insulin release","volume":"109","author":"Hsu","year":"1981","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2020-18523_bib24","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1136\/inpract.30.3.126","article-title":"Recognition and management of pain in cattle","volume":"30","author":"Hudson","year":"2008","journal-title":"In Pract."},{"key":"10.3168\/jds.2020-18523_bib25","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/35053509","article-title":"The molecular dynamics of pain control","volume":"2","author":"Hunt","year":"2001","journal-title":"Nat. Rev. Neurosci."},{"key":"10.3168\/jds.2020-18523_bib26","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1136\/vr.159.20.662","article-title":"Current attitudes of cattle practitioners to pain and the use of analgesics in cattle","volume":"159","author":"Huxley","year":"2006","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2020-18523_bib27","first-page":"308","article-title":"Laparoskopische Reposition und Fixation des nach links verlagerten Labmagens beim Rind","volume":"26","author":"Janowitz","year":"1998","journal-title":"Tierarztl. Prax. (G)"},{"key":"10.3168\/jds.2020-18523_bib28","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.3168\/jds.2011-4586","article-title":"Associations of subclinical hypocalcemia at calving with milk yield, and feeding, drinking, and standing behaviors around parturition in Holstein cows","volume":"95","author":"Jawor","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib29","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1136\/vr.162.23.743","article-title":"Milk yield and survival of Holstein-Friesian dairy cattle after laparoscopic correction of left-displaced abomasum","volume":"162","author":"Jorritsma","year":"2008","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2020-18523_bib30","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.theriogenology.2019.08.011","article-title":"Injectable or transdermal flunixin meglumine improves pregnancy rates in embryo transfer recipient beef cows without altering returns to estrus","volume":"140","author":"Kasimanickam","year":"2019","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2020-18523_bib31","series-title":"Pharmakotherapie bei Haus- und Nutztieren","first-page":"63","article-title":"Pharmaka mit Wirkung auf das Zentralnervensystem","author":"L\u00f6scher","year":"2003"},{"key":"10.3168\/jds.2020-18523_bib32","first-page":"93","article-title":"Comparison of effects of xylazine, detomidine and medetomidine on heart rate, respiratory rate and blood glucose level in sheep","volume":"31","author":"Malhi","year":"2015","journal-title":"Pak. J. Agric. Eng. Vet. Sci."},{"key":"10.3168\/jds.2020-18523_bib33","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0034-5288(98)90010-8","article-title":"Effects of regional analgesia and\/or a non-steroidal anti-inflammatory analgesic on the acute cortisol response to dehorning in calves","volume":"64","author":"McMeekan","year":"1998","journal-title":"Res. Vet. Sci."},{"key":"10.3168\/jds.2020-18523_bib34","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.tvjl.2009.08.020","article-title":"Cardiopulmonary effects of dorsal recumbency and high-volume caudal epidural anaesthesia with lidocaine or xylazine in calves","volume":"186","author":"Meyer","year":"2010","journal-title":"Vet. J."},{"key":"10.3168\/jds.2020-18523_bib35","first-page":"121","article-title":"Effects of diazepam and xylazine on changes of blood oxygen and glucose levels in mice","volume":"6","author":"Mohammed","year":"2018","journal-title":"Adv. Anim. Vet. Sci."},{"key":"10.3168\/jds.2020-18523_bib36","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2527\/1997.751266x","article-title":"Assessment of acute pain in farm animals using behavioral and physiological measurements","volume":"75","author":"Molony","year":"1997","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2020-18523_bib37","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2754\/avb200574010037","article-title":"Stress response in dairy cows related to different blood glucose","volume":"74","author":"Mudro\u0148","year":"2005","journal-title":"Acta Vet. Brno"},{"key":"10.3168\/jds.2020-18523_bib38","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/inp.d6079","article-title":"Diagnosis, treatment and control of left displaced abomasum in cattle","volume":"33","author":"Mueller","year":"2011","journal-title":"In Pract."},{"key":"10.3168\/jds.2020-18523_bib39","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.2460\/javma.2001.219.1346","article-title":"Mechanisms of pain and their therapeutic implications","volume":"219","author":"Muir","year":"2001","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.3168\/jds.2020-18523_bib40","series-title":"Schmerztherapie bei Klein-, Heim- und Versuchstieren","first-page":"51","article-title":"5. Schmerztherapie","author":"Otto","year":"2001"},{"key":"10.3168\/jds.2020-18523_bib41","first-page":"288","article-title":"Comparison of two methods of fixation during functional claw trimming-walk-in crush versus tilt table-in dairy cows using faecal cortisol metabolite concentrations and daily milk yield as parameters","volume":"93","author":"Pesenhofer","year":"2006","journal-title":"Wien. Tier\u00e4rztl. Mschr."},{"key":"10.3168\/jds.2020-18523_bib42","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.2460\/javma.240.10.1223","article-title":"Effects of xylazine hydrochloride on hormonal, metabolic, and cardiorespiratory stress responses to lateral recumbency and claw trimming in dairy cows","volume":"240","author":"Rizk","year":"2012","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.3168\/jds.2020-18523_bib43","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.tvjl.2011.05.022","article-title":"The use of xylazine hydrochloride in an analgesic protocol for claw treatment of lame dairy cows in lateral recumbency on a surgical tipping table","volume":"192","author":"Rizk","year":"2012","journal-title":"Vet. J."},{"key":"10.3168\/jds.2020-18523_bib44","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.3168\/jds.2016-12305","article-title":"Evaluation and validation of an automatic jaw movement recorder (RumiWatch) for ingestive and rumination behaviors of dairy cows during grazing and supplementation","volume":"101","author":"Rombach","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib45","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.3168\/jds.2018-14834","article-title":"Herbage dry matter intake estimation of grazing dairy cows based on animal, behavioral, environmental, and feed variables","volume":"102","author":"Rombach","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2020-18523_bib46","series-title":"Farm Animal Surgery","first-page":"280","article-title":"Laparoscopic Abomasopexy","volume":"Vol. 2","author":"Roy","year":"2017"},{"key":"10.3168\/jds.2020-18523_bib47","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.applanim.2011.04.005","article-title":"Impact of acute clinical mastitis on cow behaviour","volume":"132","author":"Siivonen","year":"2011","journal-title":"Appl. Anim. Behav. Sci."},{"key":"10.3168\/jds.2020-18523_bib48","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1053\/eujp.2000.0171","article-title":"Substance P","volume":"4","author":"Snijdelaar","year":"2000","journal-title":"Eur. J. Pain"},{"key":"10.3168\/jds.2020-18523_bib49","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/S0093-691X(97)00098-8","article-title":"A lameness scoring system that uses posture and gait to predict dairy cattle reproductive performance","volume":"47","author":"Sprecher","year":"1997","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2020-18523_bib50","series-title":"Die klinische Untersuchung des Rindes","first-page":"37","article-title":"Beruhigung, Niederlegen und Schmerzausschaltung durch Medikamente","author":"St\u00f6ber","year":"1990"},{"key":"10.3168\/jds.2020-18523_bib51","series-title":"Farm Animal Surgery","first-page":"260","article-title":"Surgery of the abomasum","author":"Trent","year":"2017"},{"key":"10.3168\/jds.2020-18523_bib52","first-page":"522","article-title":"Course of plasma substance P concentrations during umbilical surgery in calves","volume":"131","author":"Tschoner","year":"2018","journal-title":"Berl. Munch. Tierarztl. Wochenschr."},{"key":"10.3168\/jds.2020-18523_bib53","doi-asserted-by":"crossref","first-page":"498","DOI":"10.2527\/jas.2013-6857","article-title":"Impact of oral meloxicam on circulation physiological biomarkers of stress and inflammation in beef steers after long distance transportation","volume":"92","author":"Van Engen","year":"2014","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2020-18523_bib54","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.theriogenology.2012.03.020","article-title":"Electroejaculation increased vocalization and plasma concentrations of cortisol and progesterone, but not substance P, in beef bulls","volume":"78","author":"Whitlock","year":"2012","journal-title":"Theriogenology"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030220305889?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030220305889?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030220305889","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T21:40:38Z","timestamp":1749850838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030220305889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":54,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S0022030220305889"],"URL":"https:\/\/doi.org\/10.3168\/jds.2020-18523","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of xylazine administration before laparoscopic abomasopexy to correct left displaced abomasum on markers of stress in dairy cows","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2020-18523","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 American Dairy Science Association\u00ae.","name":"copyright","label":"Copyright"}]}}