{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:25:56Z","timestamp":1790738756617,"version":"4.1.0"},"reference-count":35,"publisher":"American Dairy Science Association","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.3168\/jds.2021-20680","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T03:27:28Z","timestamp":1629948448000},"page":"12117-12126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Feeding milk supplemented with Ulva sp., Ascophyllum nodosum, or Saccharina latissima to preweaning dairy calves: Effects on growth, gut microbiota, gut histomorphology, and short-chain fatty acids in digesta"],"prefix":"10.3168","volume":"104","author":[{"given":"M.B.","family":"Samarasinghe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sehested","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Weisbjerg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"van der Heide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.V.","family":"N\u00f8rgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vestergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.E.","family":"Hern\u00e1ndez-Castellano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2021-20680_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110625","article-title":"Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics","volume":"130","author":"Ashaolu","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.3168\/jds.2021-20680_bib2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting linear mixed-effects models using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"J. Stat. Softw."},{"key":"10.3168\/jds.2021-20680_bib3","author":"Biostuff"},{"key":"10.3168\/jds.2021-20680_bib4","doi-asserted-by":"crossref","first-page":"630","DOI":"10.15232\/aas.2020-02049","article-title":"Invited Review: Strategic use of microbial-based probiotics and prebiotics in dairy calf rearing","volume":"36","author":"Cangiano","year":"2020","journal-title":"Appl. Anim. Sci."},{"key":"10.3168\/jds.2021-20680_bib5","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/jsfa.3480","article-title":"Effect of feeding intact brown seaweed Ascophyllum nodosum on some digestive parameters and on iodine content in edible tissues in pigs","volume":"89","author":"Dierick","year":"2009","journal-title":"J. Sci. Food Agric."},{"key":"10.3168\/jds.2021-20680_bib6","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.3168\/jds.2017-13870","article-title":"The effect of lung consolidation, as determined by ultrasonography, on first-lactation milk production in Holstein dairy calves","volume":"101","author":"Dunn","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2021-20680_bib7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1006\/mcpr.2001.0354","article-title":"Automated 5\u2032 nuclease assay for detection of virulence factors in porcine Escherichia coli","volume":"15","author":"Frydendahl","year":"2001","journal-title":"Mol. Cell. Probes"},{"key":"10.3168\/jds.2021-20680_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1017\/S1751731108003017","article-title":"Performance of weanling piglets offered low-, medium- or high-lactose diets supplemented with a seaweed extract from Laminaria spp","volume":"3","author":"Gahan","year":"2009","journal-title":"Animal"},{"key":"10.3168\/jds.2021-20680_bib9","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.2527\/2005.8371554x","article-title":"Effect of feed particle size and feed processing on morphological characteristics in the small and large intestine of pigs and on adhesion of Salmonella enterica serovar Typhimurium DT12 in the ileum in vitro","volume":"83","author":"Hedemann","year":"2005","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2021-20680_bib10","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3168\/jds.2010-3170","article-title":"A prospective study of calf factors affecting first-lactation and lifetime milk production and age of cows when removed from the herd","volume":"94","author":"Heinrichs","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2021-20680_bib11","doi-asserted-by":"crossref","first-page":"368","DOI":"10.15232\/pas.2015-01390","article-title":"Effect of feeding kelp on growth and profitability of group-fed calves in an organic production system","volume":"31","author":"Heins","year":"2015","journal-title":"Prof. Anim. Sci."},{"key":"10.3168\/jds.2021-20680_bib12","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1186\/1471-2164-14-788","article-title":"The Gut Microbiotassay: A high-throughput qPCR approach combinable with next generation sequencing to study gut microbial diversity","volume":"14","author":"Hermann-Bank","year":"2013","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2021-20680_bib13","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.3168\/jds.2015-10198","article-title":"Stress, immunity, and the management of calves","volume":"99","author":"Hulbert","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2021-20680_bib14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1017\/S1751731110001710","article-title":"Gastrointestinal development of dairy calves fed low-or high-starch concentrate at two milk allowances","volume":"5","author":"Kosiorowska","year":"2011","journal-title":"Animal"},{"key":"10.3168\/jds.2021-20680_bib15","first-page":"26","article-title":"Portal recovery of intraruminally infused short-chain fatty acids in sheep","volume":"46","author":"Kristensen","year":"1996","journal-title":"Acta Agric. Scand. A Anim."},{"key":"10.3168\/jds.2021-20680_bib16","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ab.2017.10.026","article-title":"Fluorometric determination of d-lactate in biological fluids","volume":"539","author":"Larsen","year":"2017","journal-title":"Anal. Biochem."},{"key":"10.3168\/jds.2021-20680_bib17","author":"Lenth"},{"key":"10.3168\/jds.2021-20680_bib18","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/2046-0481-64-9","article-title":"Calf health from birth to weaning. II. Management of diarrhoea in pre-weaned calves","volume":"64","author":"Lorenz","year":"2011","journal-title":"Ir. Vet. J."},{"key":"10.3168\/jds.2021-20680_bib19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3389\/fvets.2015.00036","article-title":"The gut microbiome and its potential role in the development and function of newborn calf gastrointestinal tract","volume":"2","author":"Malmuthuge","year":"2015","journal-title":"Front. Vet. Sci."},{"key":"10.3168\/jds.2021-20680_bib20","doi-asserted-by":"crossref","first-page":"e02534","DOI":"10.1128\/AEM.02534-18","article-title":"Taxonomic and functional compositions of the small intestinal microbiome in neonatal calves provide a framework for understanding early life gut health","volume":"85","author":"Malmuthuge","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"issue":"Suppl. 3","key":"10.3168\/jds.2021-20680_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2527\/jas.2015-9779","article-title":"Effects of dietary supplementation of galactooligosaccharides and seaweed-derived polysaccharides on an experimental Salmonella typhimurium challenge in pigs","volume":"94","author":"McDonnell","year":"2016","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2021-20680_bib22","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1017\/S1751731109991376","article-title":"The effect of dietary laminarin and fucoidan in the diet of the weanling piglet on performance, selected faecal microbial populations and volatile fatty acid concentrations","volume":"4","author":"McDonnell","year":"2010","journal-title":"Animal"},{"key":"10.3168\/jds.2021-20680_bib23","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1111\/j.1439-0396.2011.01227.x","article-title":"Intact brown seaweed (Ascophyllum nodosum) in diets of weaned piglets: Effects on performance, gut bacteria and morphology and plasma oxidative status","volume":"96","author":"Michiels","year":"2012","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl.)"},{"key":"10.3168\/jds.2021-20680_bib24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/jsfa.9143","article-title":"Marine macroalgae as sources of protein and bioactive compounds in feed for monogastric animals","volume":"99","author":"\u00d8verland","year":"2019","journal-title":"J. Sci. Food Agric."},{"key":"10.3168\/jds.2021-20680_bib25","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1017\/S1751731108002711","article-title":"The effects of seaweed extract inclusion on gut morphology, selected intestinal microbiota, nutrient digestibility, volatile fatty acid concentrations and the immune status of the weaned pig","volume":"2","author":"Reilly","year":"2008","journal-title":"Animal"},{"key":"10.3168\/jds.2021-20680_bib26","doi-asserted-by":"crossref","first-page":"3575","DOI":"10.3168\/jds.2020-19528","article-title":"Milk supplemented with dried seaweed affects the systemic innate immune response in preweaning dairy calves","volume":"104","author":"Samarasinghe","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2021-20680_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.anifeedsci.2021.115005","article-title":"A descriptive chemical analysis of seaweeds, Ulva sp., Saccharina latissima and Ascophyllum nodosum harvested from Danish and Icelandic waters","volume":"278","author":"Samarasinghe","year":"2021","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.3168\/jds.2021-20680_bib28","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1080\/09670262.2019.1597925","article-title":"Cryptic, alien and lost species: Molecular diversity of Ulva sensu lato along the German coasts of the North and Baltic Seas","volume":"54","author":"Steinhagen","year":"2019","journal-title":"Eur. J. Phycol."},{"key":"10.3168\/jds.2021-20680_bib29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0167-5877(03)00046-1","article-title":"Morbidity in Swedish dairy calves from birth to 90 days of age and individual calf-level risk factors for infectious diseases","volume":"58","author":"Svensson","year":"2003","journal-title":"Prev. Vet. Med."},{"key":"10.3168\/jds.2021-20680_bib30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.anifeedsci.2011.02.010","article-title":"Evaluation of seaweed-derived polysaccharides on indices of gastrointestinal fermentation and selected populations of microbiota in newly weaned pigs challenged with Salmonella typhimurium","volume":"165","author":"Sweeney","year":"2011","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.3168\/jds.2021-20680_bib31","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1093\/jn\/133.11.3717","article-title":"Glucagon-like peptide-2 and short-chain fatty acids: A new twist to an old story","volume":"133","author":"Tappenden","year":"2003","journal-title":"J. Nutr."},{"key":"10.3168\/jds.2021-20680_bib32","author":"USDA"},{"key":"10.3168\/jds.2021-20680_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.watres.2017.08.032","article-title":"A highly specific Escherichia coli qPCR and its comparison with existing methods for environmental waters","volume":"126","author":"Walker","year":"2017","journal-title":"Water Res."},{"key":"10.3168\/jds.2021-20680_bib34","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.3168\/jds.2011-4727","article-title":"Characteristics of dairy calf ranches: Morbidity, mortality, antibiotic use practices, and biosecurity and biocontainment practices","volume":"95","author":"Walker","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2021-20680_bib35","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.prevetmed.2013.10.019","article-title":"Factors associated with morbidity, mortality, and growth of dairy heifer calves up to 3 months of age","volume":"113","author":"Windeyer","year":"2014","journal-title":"Prev. Vet. Med."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030221008456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030221008456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030221008456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:19:22Z","timestamp":1731100762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030221008456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S0022030221008456"],"URL":"https:\/\/doi.org\/10.3168\/jds.2021-20680","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feeding milk supplemented with Ulva sp., Ascophyllum nodosum, or Saccharina latissima to preweaning dairy calves: Effects on growth, gut microbiota, gut histomorphology, and short-chain fatty acids in digesta","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2021-20680","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Dairy Science Association\u00ae.","name":"copyright","label":"Copyright"}]}}