{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T17:59:28Z","timestamp":1787075968797,"version":"build-2736575974"},"reference-count":43,"publisher":"American Dairy Science Association","issue":"7","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.3168\/jds.2022-22979","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T10:32:09Z","timestamp":1685615529000},"page":"5029-5042","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Association of time to metritis diagnosis with circulating concentration of metabolites, minerals, and haptoglobin in Jersey cows"],"prefix":"10.3168","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1281-3693","authenticated-orcid":false,"given":"P.R.","family":"Menta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6595-3879","authenticated-orcid":false,"given":"R.C.","family":"Neves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1513-8216","authenticated-orcid":false,"given":"V.S.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2022-22979_bib1","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.3168\/jds.2013-7832","article-title":"Effect of trace mineral supplementation on selected minerals, energy metabolites, oxidative stress, and immune parameters and its association with uterine diseases in dairy cattle","volume":"97","author":"Bicalho","year":"2014","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib2","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.theriogenology.2016.09.036","article-title":"The association of plasma glucose, BHBA, and NEFA with postpartum uterine diseases, fertility, and milk production of Holstein dairy cows","volume":"88","author":"Bicalho","year":"2017","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2022-22979_bib3","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1189\/jlb.0807553","article-title":"Regulation of superoxide production in neutrophils: Role of calcium influx","volume":"84","author":"Br\u00e9chard","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.3168\/jds.2022-22979_bib4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.livsci.2018.08.003","article-title":"Plasma fructosamine during the transition period and its relationship with energy metabolism and inflammation biomarkers in dairy cows","volume":"216","author":"Car\u00e9","year":"2018","journal-title":"Livest. Sci."},{"key":"10.3168\/jds.2022-22979_bib5","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1016\/j.jprot.2012.04.004","article-title":"Acute phase proteins in ruminants","volume":"75","author":"Ceciliani","year":"2012","journal-title":"J. Proteomics"},{"key":"10.3168\/jds.2022-22979_bib6","doi-asserted-by":"crossref","first-page":"589","DOI":"10.3168\/jds.S0022-0302(76)84245-2","article-title":"Composition of the milks of dairy cattle. II. Ash, calcium, magnesium, and phosphorus","volume":"59","author":"Cerbulis","year":"1976","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib7","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.3168\/jds.2010-4075","article-title":"The association of serum metabolites with clinical disease during the transition period","volume":"94","author":"Chapinal","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib8","doi-asserted-by":"crossref","first-page":"7377","DOI":"10.3168\/jds.2019-18028","article-title":"Using chitosan microparticles to treat metritis in lactating dairy cows","volume":"103","author":"de Oliveira","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib9","doi-asserted-by":"crossref","first-page":"12887","DOI":"10.3168\/jds.2021-20262","article-title":"Integration of statistical inferences and machine learning algorithms for prediction of metritis cure in dairy cows","volume":"104","author":"de Oliveira","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib10","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40104-016-0085-9","article-title":"Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows","volume":"7","author":"Dervishi","year":"2016","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.3168\/jds.2022-22979_bib11","doi-asserted-by":"crossref","first-page":"5764","DOI":"10.3168\/jds.2010-3429","article-title":"Risk factors for postpartum uterine diseases in dairy cows","volume":"93","author":"Dubuc","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib12","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","author":"Ferguson","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib13","doi-asserted-by":"crossref","first-page":"7056","DOI":"10.3168\/jds.2020-19661","article-title":"Failure of clinical cure in dairy cows treated for metritis is associated with reduced productive and reproductive performance","volume":"104","author":"Figueiredo","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.01066-20","article-title":"Effect of chitosan microparticles on the uterine microbiome of dairy cows with metritis","volume":"86","author":"Galv\u00e3o","year":"2020","journal-title":"Appl. Environ. Microbiol."},{"key":"10.3168\/jds.2022-22979_bib15","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.3168\/jds.2009-2551","article-title":"Association between uterine disease and indicators of neutrophil and systemic energy status in lactating Holstein cows","volume":"93","author":"Galv\u00e3o","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib16","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.3168\/jds.2012-5922","article-title":"Metritis in dairy cows: Risk factors and reproductive performance","volume":"96","author":"Giuliodori","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib17","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.vetimm.2006.03.022","article-title":"Neutrophil function and energy status in Holstein cows with uterine health disorders","volume":"113","author":"Hammon","year":"2006","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2022-22979_bib18","first-page":"641","article-title":"Bovine uterine defense mechanisms: A review","volume":"36","author":"Hussain","year":"1989","journal-title":"Zentralbl Veterinarmed B"},{"key":"10.3168\/jds.2022-22979_bib19","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3168\/jds.2008-1526","article-title":"Short communication: Haptoglobin as an early indicator of metritis","volume":"92","author":"Huzzey","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib20","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.prevetmed.2015.04.011","article-title":"Associations of peripartum markers of stress and inflammation with milk yield and reproductive performance in Holstein dairy cows","volume":"120","author":"Huzzey","year":"2015","journal-title":"Prev. Vet. Med."},{"key":"10.3168\/jds.2022-22979_bib21","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.3168\/jds.S0022-0302(99)75489-5","article-title":"Effects of the presence of the mammary gland on expression of neutrophil adhesion molecules and myeloperoxidase activity in periparturient dairy cows","volume":"82","author":"Kimura","year":"1999","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib22","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.anireprosci.2013.12.016","article-title":"Associations between resumption of postpartum ovarian activity, uterine health and concentrations of metabolites and acute phase proteins during the transition period in Holstein cows","volume":"145","author":"Krause","year":"2014","journal-title":"Anim. Reprod. Sci."},{"issue":"Suppl 5","key":"10.3168\/jds.2022-22979_bib23","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1439-0531.2012.02109.x","article-title":"Interactions of metabolism, inflammation, and reproductive tract health in the postpartum period in dairy cattle","volume":"47","author":"LeBlanc","year":"2012","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2022-22979_bib24","doi-asserted-by":"crossref","first-page":"7345","DOI":"10.3168\/jds.2018-15383","article-title":"Economic comparison of systemic antimicrobial therapies for metritis in dairy cows","volume":"102","author":"Lima","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib25","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1111\/1462-2920.13097","article-title":"Soil-borne reservoirs of antibiotic-resistant bacteria are established following therapeutic treatment of dairy calves","volume":"18","author":"Liu","year":"2016","journal-title":"Environ. Microbiol."},{"key":"10.3168\/jds.2022-22979_bib26","doi-asserted-by":"crossref","first-page":"9261","DOI":"10.3168\/jds.2020-18643","article-title":"The association of cow-related factors assessed at metritis diagnosis with metritis cure risk, reproductive performance, milk yield, and culling for untreated and ceftiofur-treated dairy cows","volume":"103","author":"Machado","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1292\/jvms1939.44.15","article-title":"Quantitative determination of bovine serum Haptoglobin and its elevation in some inflammatory diseases","volume":"44","author":"Makimura","year":"1982","journal-title":"Nippon Juigaku Zasshi"},{"key":"10.3168\/jds.2022-22979_bib28","doi-asserted-by":"crossref","first-page":"750","DOI":"10.3168\/jds.2020-18867","article-title":"Calving difficulty influences rumination time and inflammatory profile in Holstein dairy cows","volume":"104","author":"Mammi","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib29","doi-asserted-by":"crossref","first-page":"7158","DOI":"10.3168\/jds.2012-5812","article-title":"Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease","volume":"95","author":"Martinez","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib30","doi-asserted-by":"crossref","first-page":"6113","DOI":"10.3168\/jds.2020-19538","article-title":"Prolonged, low-grade inflammation in the first week of lactation: Associations with mineral, protein, and energy balance markers, and milk yield, in a clinically healthy Jersey cow cohort","volume":"104","author":"Martins","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib31","doi-asserted-by":"crossref","first-page":"5854","DOI":"10.3168\/jds.2020-19189","article-title":"Association of blood calcium concentration in the first 3 days after parturition and energy balance metabolites at day 3 in milk with disease and production outcomes in multiparous Jersey cows","volume":"104","author":"Menta","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.prevetmed.2021.105431","article-title":"Predictive models to identify Holstein cows at risk of metritis and clinical cure and reproductive\/productive failure following antimicrobial treatment","volume":"194","author":"Merenda","year":"2021","journal-title":"Prev. Vet. Med."},{"key":"10.3168\/jds.2022-22979_bib33","doi-asserted-by":"crossref","first-page":"547","DOI":"10.3168\/jds.2017-13313","article-title":"Association of immediate postpartum plasma calcium concentration with early-lactation clinical diseases, culling, reproduction, and milk production in Holstein cows","volume":"101","author":"Neves","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib34","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.vetimm.2014.12.016","article-title":"Elevated plasma haptoglobin concentrations following parturition are associated with elevated leukocyte responses and decreased subsequent reproductive efficiency in multiparous Holstein dairy cows","volume":"164","author":"Nightingale","year":"2015","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2022-22979_bib35","doi-asserted-by":"crossref","first-page":"4374","DOI":"10.3168\/jds.2010-3195","article-title":"Energy balance in first-lactation Holstein, Jersey, and reciprocal F1 crossbred cows in a planned crossbreeding experiment","volume":"93","author":"Olson","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib36","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1095\/biolreprod.109.077370","article-title":"Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle","volume":"81","author":"Sheldon","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2022-22979_bib37","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2022-22979_bib38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.tvjl.2007.12.031","article-title":"Uterine diseases in cattle after parturition","volume":"176","author":"Sheldon","year":"2008","journal-title":"Vet. J."},{"key":"10.3168\/jds.2022-22979_bib39","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.2460\/ajvr.67.10.1696","article-title":"Association between ceftiofur use and isolation of Escherichia coli with reduced susceptibility to ceftriaxone from fecal samples of dairy cows","volume":"67","author":"Tragesser","year":"2006","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2022-22979_bib40","first-page":"285","article-title":"Pro-inflammatory cytokine profile in dairy cows: Consequences for new lactation","volume":"14","author":"Trevisi","year":"2016","journal-title":"Ital. J. Anim. Sci."},{"key":"10.3168\/jds.2022-22979_bib41","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.3168\/jds.S0022-0302(94)77092-2","article-title":"Peripartum liver triglyceride and plasma metabolites in dairy cows","volume":"77","author":"Vazquez-A\u00f1on","year":"1994","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22979_bib42","doi-asserted-by":"crossref","first-page":"46616","DOI":"10.1074\/jbc.M307155200","article-title":"Modification of proteins in vitro by physiological levels of glucose: Pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions","volume":"278","author":"Voziyan","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2022-22979_bib43","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.3168\/jds.2010-3697","article-title":"Short communication: Metritis affects milk production and cull rate of Holstein multiparous and primiparous dairy cows differently","volume":"94","author":"Wittrock","year":"2011","journal-title":"J. Dairy Sci."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223003053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223003053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223003053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:38:03Z","timestamp":1731101883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223003053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":43,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S0022030223003053"],"URL":"https:\/\/doi.org\/10.3168\/jds.2022-22979","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of time to metritis diagnosis with circulating concentration of metabolites, minerals, and haptoglobin in Jersey cows","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2022-22979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s).","name":"copyright","label":"Copyright"}]}}