{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:46:49Z","timestamp":1785714409107,"version":"3.56.0"},"reference-count":60,"publisher":"American Dairy Science Association","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.3168\/jds.2022-22983","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T01:50:15Z","timestamp":1705629015000},"page":"555-572","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Interferon-tau protects bovine endometrial epithelial cells against inflammatory injury by regulating the PI3K\/AKT\/\u03b2-catenin\/FoxO1 signaling axis"],"prefix":"10.3168","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9248-0723","authenticated-orcid":false,"given":"Kangfeng","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5046-6322","authenticated-orcid":false,"given":"Jinyin","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9522-4856","authenticated-orcid":false,"given":"Qianming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1586-4365","authenticated-orcid":false,"given":"Juan J.","family":"Loor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0813-927X","authenticated-orcid":false,"given":"Ganzhen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9105-6365","authenticated-orcid":false,"given":"Xiaobing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0768-6773","authenticated-orcid":false,"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2022-22983_bib1","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0092-8674(04)00452-0","article-title":"FoxOs at the crossroads of cellular metabolism, differentiation, and transformation","volume":"117","author":"Accili","year":"2004","journal-title":"Cell"},{"key":"10.3168\/jds.2022-22983_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.cellimm.2010.02.012","article-title":"Type I interferon (IFN-alpha\/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta\/Akt, Rho-A, NFkappaB and Bcl-2\/Bcl(XL)","volume":"263","author":"Badr","year":"2010","journal-title":"Cell. Immunol."},{"key":"10.3168\/jds.2022-22983_bib3","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1172\/JCI34431","article-title":"A calculated response: Control of inflammation by the innate immune system","volume":"118","author":"Barton","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2022-22983_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1600-0897.1996.tb00485.x","article-title":"Placental interferons","volume":"35","author":"Bazer","year":"1996","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.3168\/jds.2022-22983_bib5","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1600-0897.1997.tb00253.x","article-title":"Interferon tau: A novel pregnancy recognition signal","volume":"37","author":"Bazer","year":"1997","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.3168\/jds.2022-22983_bib6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.vetmic.2011.11.034","article-title":"Association between virulence factors of Escherichia coli, Fusobacterium necrophorum, and Arcanobacterium pyogenes and uterine diseases of dairy cows","volume":"157","author":"Bicalho","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.3168\/jds.2022-22983_bib7","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1095\/biolreprod64.2.654","article-title":"Bovine interferon-tau stimulates the Janus kinase-signal transducer and activator of transcription pathway in bovine endometrial epithelial cells","volume":"64","author":"Binelli","year":"2001","journal-title":"Biol. Reprod."},{"issue":"Suppl 2","key":"10.3168\/jds.2022-22983_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2527\/1999.77suppl_2101x","article-title":"Inflammation in the bovine female reproductive tract","volume":"77","author":"Bondurant","year":"1999","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2022-22983_bib9","doi-asserted-by":"crossref","first-page":"4261","DOI":"10.4049\/jimmunol.154.9.4261","article-title":"IL-10 prevents naturally occurring fetal loss in the CBA x DBA\/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau","volume":"154","author":"Chaouat","year":"1995","journal-title":"J. Immunol."},{"key":"10.3168\/jds.2022-22983_bib10","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/rda.12287","article-title":"IFN-\u03c4 acts in a dose-dependent manner on prostaglandin production by buffalo endometrial stromal cells cultured in vitro","volume":"49","author":"Chethan","year":"2014","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2022-22983_bib11","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1089\/jir.2009.0089","article-title":"Interferon-\u03c4: Current applications and potential in antiviral therapy","volume":"30","author":"Chon","year":"2010","journal-title":"J. Interferon Cytokine Res."},{"key":"10.3168\/jds.2022-22983_bib12","doi-asserted-by":"crossref","first-page":"5225","DOI":"10.3168\/jds.2010-3428","article-title":"Definitions and diagnosis of postpartum endometritis in dairy cows","volume":"93","author":"Dubuc","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib13","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1038\/emboj.2010.268","article-title":"FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages","volume":"29","author":"Fan","year":"2010","journal-title":"EMBO J."},{"key":"10.3168\/jds.2022-22983_bib14","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ctrv.2003.07.007","article-title":"PI3K\/Akt signalling pathway and cancer","volume":"30","author":"Fresno Vara","year":"2004","journal-title":"Cancer Treat. Rev."},{"key":"10.3168\/jds.2022-22983_bib15","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.anireprosci.2017.10.005","article-title":"PTGER2 activation induces PTGS-2 and growth factor gene expression in endometrial epithelial cells of cattle","volume":"187","author":"Gao","year":"2017","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2022-22983_bib16","doi-asserted-by":"crossref","first-page":"32124","DOI":"10.1074\/jbc.M203298200","article-title":"The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells","volume":"277","author":"Guha","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2022-22983_bib17","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1038\/cdd.2016.101","article-title":"Leishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of \u03b2-catenin and FOXO-1","volume":"23","author":"Gupta","year":"2016","journal-title":"Cell Death Differ."},{"key":"10.3168\/jds.2022-22983_bib18","doi-asserted-by":"crossref","first-page":"F45","DOI":"10.1530\/REP-17-0315","article-title":"Paracrine and endocrine actions of interferon tau (IFNT)","volume":"154","author":"Hansen","year":"2017","journal-title":"Reproduction"},{"key":"10.3168\/jds.2022-22983_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113974","article-title":"Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1\u03b2 in macrophages","volume":"9","author":"Hara","year":"2014","journal-title":"PLoS One"},{"key":"10.3168\/jds.2022-22983_bib20","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1210\/en.2005-1113","article-title":"Expression and function of toll-like receptor 4 in the endometrial cells of the uterus","volume":"147","author":"Herath","year":"2006","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2022-22983_bib21","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1751-0813.2008.00326.x","article-title":"Reduced quality of bovine embryos cultured in media conditioned by exposure to an inflamed endometrium","volume":"86","author":"Hill","year":"2008","journal-title":"Aust. Vet. J."},{"key":"10.3168\/jds.2022-22983_bib22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.virusres.2010.07.002","article-title":"PI3K\/Akt signaling mediated apoptosis blockage and viral gene expression in oral epithelial cells during herpes simplex virus infection","volume":"153","author":"Hsu","year":"2010","journal-title":"Virus Res."},{"key":"10.3168\/jds.2022-22983_bib23","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1186\/s12864-020-06777-7","article-title":"LPS-treatment of bovine endometrial epithelial cells causes differential DNA methylation of genes associated with inflammation and endometrial function","volume":"21","author":"Jhamat","year":"2020","journal-title":"BMC Genomics"},{"key":"10.3168\/jds.2022-22983_bib24","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.7150\/ijbs.56933","article-title":"Enforced expression of miR-92b blunts E. coli lipopolysaccharide-mediated inflammatory injury by activating the PI3K\/AKT\/\u03b2-catenin pathway via targeting PTEN","volume":"17","author":"Jiang","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"10.3168\/jds.2022-22983_bib25","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/jcmm.14744","article-title":"miR-148a suppresses inflammation in lipopolysaccharide-induced endometritis","volume":"24","author":"Jiang","year":"2020","journal-title":"J. Cell. Mol. Med."},{"key":"10.3168\/jds.2022-22983_bib26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/hep.25958","article-title":"PTEN-mediated Akt\/\u03b2-catenin\/Foxo1 signaling regulates innate immune responses in mouse liver ischemia\/reperfusion injury","volume":"57","author":"Kamo","year":"2013","journal-title":"Hepatology"},{"key":"10.3168\/jds.2022-22983_bib27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.theriogenology.2003.03.001","article-title":"Endometrial cytology and ultrasonography for the detection of subclinical endometritis in postpartum dairy cows","volume":"62","author":"Kasimanickam","year":"2004","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2022-22983_bib28","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3109\/08923973.2011.574704","article-title":"WNT\/\u03b2-catenin pathway is modulated in asthma patients and LPS-stimulated RAW264.7 macrophage cell line","volume":"34","author":"Lee","year":"2012","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"10.3168\/jds.2022-22983_bib29","doi-asserted-by":"crossref","first-page":"10473","DOI":"10.3168\/jds.2021-20257","article-title":"The human milk oligosaccharide 2\u2032-fucosyllactose attenuates \u03b2-lactoglobulin-induced food allergy through the miR-146a-mediated toll-like receptor 4\/nuclear factor-\u03baB signaling pathway","volume":"104","author":"Li","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib30","doi-asserted-by":"crossref","first-page":"5493","DOI":"10.3168\/jds.2021-21066","article-title":"A high-concentrate diet induces an inflammatory response and oxidative stress and depresses milk fat synthesis in the mammary gland of dairy cows","volume":"105","author":"Ma","year":"2022","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib31","doi-asserted-by":"crossref","first-page":"501","DOI":"10.56093\/ijans.v89i5.90013","article-title":"Oxytetracycline is more suitable antibiotic for clinical endometritis cows","volume":"89","author":"Manimaran","year":"2019","journal-title":"Indian J. Anim. Sci."},{"key":"10.3168\/jds.2022-22983_bib32","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.3168\/jds.S0022-0302(95)76817-5","article-title":"Extension of corpus luteum lifespan and reduction of uterine secretion of prostaglandin F2\u03b1 of cows in response to recombinant interferon-\u03c4","volume":"78","author":"Meyer","year":"1995","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib33","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.pharep.2017.04.008","article-title":"Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K\/AKT and telomerase","volume":"69","author":"Moradzadeh","year":"2017","journal-title":"Pharmacol. Rep."},{"key":"10.3168\/jds.2022-22983_bib34","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1161\/01.RES.0000175241.92285.f8","article-title":"Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling","volume":"97","author":"Naito","year":"2005","journal-title":"Circ. Res."},{"key":"10.3168\/jds.2022-22983_bib35","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.3168\/jds.2018-15595","article-title":"A model of clinical endometritis in Holstein heifers using pathogenic Escherichia coli and Trueperella pyogenes","volume":"102","author":"Piersanti","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib36","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.bbrc.2018.04.178","article-title":"Evidence that interferon-tau secreted from day-7 embryo in vivo generates anti-inflammatory immune response in the bovine uterus","volume":"500","author":"Rashid","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"Suppl 1","key":"10.3168\/jds.2022-22983_bib37","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1600-0897.2011.01048.x","article-title":"Endometrial receptivity and human embryo implantation","volume":"66","author":"Rashid","year":"2011","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.3168\/jds.2022-22983_bib38","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1089\/jir.1996.16.271","article-title":"Interferon-\u03c4and Pregnancy","volume":"16","author":"Roberts","year":"1996","journal-title":"J. Interferon Cytokine Res."},{"key":"10.3168\/jds.2022-22983_bib39","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.cytogfr.2007.06.010","article-title":"Interferon-tau, a type 1 interferon involved in maternal recognition of pregnancy","volume":"18","author":"Roberts","year":"2007","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.3168\/jds.2022-22983_bib40","first-page":"186","article-title":"Strategic treatment with immunomodulators to resolve endometritis in cow: A review","volume":"37","author":"Sarkar","year":"2016","journal-title":"Agric. Rev. (Karnal)"},{"key":"10.3168\/jds.2022-22983_bib41","doi-asserted-by":"crossref","first-page":"4885","DOI":"10.1002\/jcp.26296","article-title":"JAK3 and PI3K mediate bovine interferon-tau stimulated gene expression in the blood neutrophils","volume":"233","author":"Sheikh","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.3168\/jds.2022-22983_bib42","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2005.08.021","article-title":"Defining postpartum uterine disease in cattle","volume":"65","author":"Sheldon","year":"2006","journal-title":"Theriogenology"},{"issue":"Suppl 3","key":"10.3168\/jds.2022-22983_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1439-0531.2009.01465.x","article-title":"Mechanisms of infertility associated with clinical and subclinical endometritis in high producing dairy cattle","volume":"44","author":"Sheldon","year":"2009","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2022-22983_bib44","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/08916930802194195","article-title":"Interferon-tau inhibits the development of diabetes in NOD mice","volume":"41","author":"Sobel","year":"2008","journal-title":"Autoimmunity"},{"key":"10.3168\/jds.2022-22983_bib45","doi-asserted-by":"crossref","first-page":"471","DOI":"10.5187\/JAST.2009.51.6.471","article-title":"Interferon tau in the ovine uterus","volume":"51","author":"Song","year":"2009","journal-title":"J. Anim. Sci. Technol."},{"key":"10.3168\/jds.2022-22983_bib46","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1095\/biolreprod66.2.393","article-title":"Roles of stat1, stat2, and interferon regulatory factor-9 (IRF-9) in interferon tau regulation of IRF-1","volume":"66","author":"Stewart","year":"2002","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2022-22983_bib47","doi-asserted-by":"crossref","first-page":"12270","DOI":"10.1073\/pnas.92.26.12270","article-title":"Differential recognition of the type I interferon receptor by interferons tau and alpha is responsible for their disparate cytotoxicities","volume":"92","author":"Subramaniam","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.3168\/jds.2022-22983_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-26224-8","article-title":"Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells","volume":"8","author":"Talukder","year":"2018","journal-title":"Sci. Rep."},{"key":"10.3168\/jds.2022-22983_bib49","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1262\/jrd.2017-056","article-title":"Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: Possible involvement of interferon tau as an intermediator","volume":"63","author":"Talukder","year":"2017","journal-title":"J. Reprod. Dev."},{"key":"10.3168\/jds.2022-22983_bib50","doi-asserted-by":"crossref","first-page":"8110","DOI":"10.3168\/jds.2018-14398","article-title":"Multidrug residues and antimicrobial resistance patterns in waste milk from dairy farms in Central California","volume":"101","author":"Tempini","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-22983_bib51","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1089\/ars.2008.2042","article-title":"Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium","volume":"10","author":"Thirunavukkarasu","year":"2008","journal-title":"Antioxid. Redox Signal."},{"key":"10.3168\/jds.2022-22983_bib52","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/biolre\/ioz187","article-title":"Protective effects of astaxanthin on lipopolysaccharide-induced inflammation in bovine endometrial epithelial cells","volume":"102","author":"Wan","year":"2020","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2022-22983_bib53","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1095\/biolreprod.102.006924","article-title":"Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium","volume":"68","author":"Wang","year":"2003","journal-title":"Biol. Reprod."},{"issue":"Suppl 3","key":"10.3168\/jds.2022-22983_bib54","doi-asserted-by":"crossref","first-page":"iii70","DOI":"10.1136\/ard.2008.098459","article-title":"The PI3K\/Akt\/mTOR pathway in innate immune cells: Emerging therapeutic applications","volume":"67","author":"Weichhart","year":"2008","journal-title":"Ann. Rheum. Dis."},{"key":"10.3168\/jds.2022-22983_bib55","first-page":"1141","article-title":"IFN-\u03c4 alleviates lipopolysaccharide-induced inflammation by suppressing NF-\u03baB and MAPKs pathway activation in mice","volume":"39","author":"Wu","year":"2016","journal-title":"Inflammation"},{"key":"10.3168\/jds.2022-22983_bib56","doi-asserted-by":"crossref","first-page":"9477","DOI":"10.1021\/acs.jafc.9b02925","article-title":"Porcine milk exosome miRNAs attenuate LPS-induced apoptosis through inhibiting TLR4\/NF-\u03baB and p53 pathways in intestinal epithelial cells","volume":"67","author":"Xie","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"10.3168\/jds.2022-22983_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0098835","article-title":"Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization","volume":"9","author":"Ying","year":"2014","journal-title":"PLoS One"},{"key":"10.3168\/jds.2022-22983_bib58","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/SHK.0b013e318199165d","article-title":"Cardiac-specific expression of heat shock protein 27 attenuated endotoxin-induced cardiac dysfunction and mortality in mice through a PI3K\/Akt-dependent mechanism","volume":"32","author":"You","year":"2009","journal-title":"Shock"},{"key":"10.3168\/jds.2022-22983_bib59","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.intimp.2016.02.016","article-title":"IFN-\u03c4 inhibits S. aureus-induced inflammation by suppressing the activation of NF-\u03baB and MAPKs in RAW 264.7 cells and mice with pneumonia","volume":"35","author":"Zhao","year":"2016","journal-title":"Int. Immunopharmacol."},{"key":"10.3168\/jds.2022-22983_bib60","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.neuroscience.2014.03.039","article-title":"The role of TLR4-mediated PTEN\/PI3K\/AKT\/NF-\u03baB signaling pathway in neuroinflammation in hippocampal neurons","volume":"269","author":"Zhao","year":"2014","journal-title":"Neuroscience"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223020234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223020234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223020234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:44:27Z","timestamp":1731102267000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223020234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S0022030223020234"],"URL":"https:\/\/doi.org\/10.3168\/jds.2022-22983","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interferon-tau protects bovine endometrial epithelial cells against inflammatory injury by regulating the PI3K\/AKT\/\u03b2-catenin\/FoxO1 signaling axis","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2022-22983","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024","name":"copyright","label":"Copyright"}]}}