{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:43:41Z","timestamp":1792691021323,"version":"4.5.0"},"reference-count":50,"publisher":"American Dairy Science Association","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T00:00:00Z","timestamp":1692403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["2017-67015-26772"],"award-info":[{"award-number":["2017-67015-26772"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["NYC-127945"],"award-info":[{"award-number":["NYC-127945"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.3168\/jds.2022-23156","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T19:44:27Z","timestamp":1692819867000},"page":"9323-9344","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Metabolic-digestive clinical disorders of lactating dairy cows were associated with alterations of rumination, physical activity, and lying behavior monitored by an ear-attached sensor"],"prefix":"10.3168","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9787-1528","authenticated-orcid":false,"given":"C.","family":"Rial","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1047-8035","authenticated-orcid":false,"given":"A.","family":"Laplacette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9577-4989","authenticated-orcid":false,"given":"L.","family":"Caixeta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6729-7062","authenticated-orcid":false,"given":"C.","family":"Florentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7161-6203","authenticated-orcid":false,"given":"F.","family":"Pe\u00f1a-Mosca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1455-6811","authenticated-orcid":false,"given":"J.O.","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2022-23156_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-5573-8-1","article-title":"WINPEPI updated: Computer programs for epidemiologists, and their teaching potential","volume":"8","author":"Abramson","year":"2011","journal-title":"Epidemiol. Perspect. Innov."},{"key":"10.3168\/jds.2022-23156_bib2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.theriogenology.2021.08.002","article-title":"Transition cow metabolites and physical traits influence days to first postpartum ovulation in dairy cows","volume":"173","author":"Banuelos","year":"2021","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2022-23156_bib3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0301-6226(03)00040-X","article-title":"Effects of health disorders on feed intake and milk production in dairy cows","volume":"83","author":"Bareille","year":"2003","journal-title":"Livest. Prod. Sci."},{"key":"10.3168\/jds.2022-23156_bib4","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.2527\/1995.7392804x","article-title":"Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation","volume":"73","author":"Bell","year":"1995","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2022-23156_bib5","doi-asserted-by":"crossref","first-page":"7458","DOI":"10.3168\/jds.2015-10843","article-title":"A validation of technologies monitoring dairy cow feeding, ruminating, and lying behaviors","volume":"99","author":"Borchers","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00580-018-2863-6","article-title":"An immunoturbidimetric assay for bovine haptoglobin","volume":"28","author":"Brady","year":"2019","journal-title":"Comp. Clin. Pathol."},{"key":"10.3168\/jds.2022-23156_bib7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cvfa.2017.10.002","article-title":"Herd-level monitoring and prevention of displaced abomasum in dairy cattle","volume":"34","author":"Caixeta","year":"2018","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.3168\/jds.2022-23156_bib8","doi-asserted-by":"crossref","first-page":"11701","DOI":"10.3168\/jds.2019-17025","article-title":"Long-term effects of postpartum clinical disease on milk production, reproduction, and culling of dairy cows","volume":"102","author":"Carvalho","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib9","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1016\/j.jprot.2012.04.004","article-title":"Acute phase proteins in ruminants","volume":"75","author":"Ceciliani","year":"2012","journal-title":"J. Proteomics"},{"key":"10.3168\/jds.2022-23156_bib10","doi-asserted-by":"crossref","first-page":"5676","DOI":"10.3168\/jds.2011-5132","article-title":"Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance","volume":"95","author":"Chapinal","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib11","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.3168\/jds.2016-12144","article-title":"A dairy herd-level study of postpartum diseases and their association with reproductive performance and culling","volume":"100","author":"Dubuc","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib12","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF02600369","article-title":"An automated biochemical assay for haptoglobin: Prevention of interference from albumin","volume":"9","author":"Eckersall","year":"1999","journal-title":"Comp. Haematol. Int."},{"key":"10.3168\/jds.2022-23156_bib13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/vr.148.2.35","article-title":"Acute phase proteins in serum and milk from dairy cows with clinical mastitis","volume":"148","author":"Eckersall","year":"2001","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2022-23156_bib14","doi-asserted-by":"crossref","first-page":"9319","DOI":"10.3168\/jds.2016-11178","article-title":"Fresh-cow handling practices and methods for identification of health disorders on 45 dairy farms in California","volume":"99","author":"Espadamala","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib15","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3168\/jds.2011-4350","article-title":"Sickness behavior in dairy cows during Escherichia coli mastitis","volume":"95","author":"Fogsgaard","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib16","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.3168\/jds.S0022-0302(97)76055-7","article-title":"Physiological changes at parturition and their relationship to metabolic disorders","volume":"80","author":"Goff","year":"1997","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib17","doi-asserted-by":"crossref","first-page":"966","DOI":"10.3168\/jds.S0022-0302(98)75657-7","article-title":"Effect of diseases on the culling of Holstein dairy cows in New York State","volume":"81","author":"Gr\u00f6hn","year":"1998","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib18","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.theriogenology.2020.07.028","article-title":"Sensor technology to support herd health monitoring: Using rumination duration and activity measures as unspecific variables for the early detection of dairy cows with health deviations","volume":"157","author":"Gusterer","year":"2020","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2022-23156_bib19","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0149-7634(88)80004-6","article-title":"Biological basis of the behavior of sick animals","volume":"12","author":"Hart","year":"1988","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.3168\/jds.2022-23156_bib20","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.3168\/jds.2011-4791","article-title":"On-farm evaluation of the effect of metabolic diseases on the shape of the lactation curve in dairy cows through the MilkBot lactation model","volume":"95","author":"Hostens","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib21","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3168\/jds.2008-1526","article-title":"Short communication: Haptoglobin as an early indicator of metritis","volume":"92","author":"Huzzey","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib22","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.3168\/jds.2016-11565","article-title":"Estimating US dairy clinical disease costs with a stochastic simulation model","volume":"100","author":"Liang","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib23","doi-asserted-by":"crossref","first-page":"6812","DOI":"10.3168\/jds.2014-8947","article-title":"Characterization of peripartum rumination and activity of cows diagnosed with metabolic and uterine diseases","volume":"98","author":"Liboreiro","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1017\/S0022029900024602","article-title":"Short-term associations between disease and milk-yield of dairy-cows","volume":"53","author":"Lucey","year":"1986","journal-title":"J. Dairy Res."},{"key":"10.3168\/jds.2022-23156_bib25","first-page":"273","article-title":"Prevalence of early postpartum health disorders in Holstein cows and associations with production, reproduction, and survival outcomes on Alberta dairy farms","volume":"62","author":"Macmillan","year":"2021","journal-title":"Can. Vet. J."},{"key":"10.3168\/jds.2022-23156_bib26","doi-asserted-by":"crossref","first-page":"4899","DOI":"10.2527\/jas.2012-5554","article-title":"Methodology for quantifying the behavioral activity of dairy cows in freestall barns","volume":"91","author":"Mattachini","year":"2013","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2022-23156_bib27","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00580-011-1382-5","article-title":"Evaluation of hematological and biochemical profiles in dairy cows with left displacement of the abomasum","volume":"22","author":"Mokhber Dezfouli","year":"2013","journal-title":"Comp. Clin. Pathol."},{"key":"10.3168\/jds.2022-23156_bib28","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3168\/jds.2009-2277","article-title":"Evaluation of nonesterified fatty acids and beta-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases","volume":"93","author":"Ospina","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib29","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1017\/S1751731117002932","article-title":"Rumination time and monitoring of health disorders during early lactation","volume":"12","author":"Paudyal","year":"2018","journal-title":"Animal"},{"key":"10.3168\/jds.2022-23156_bib30","first-page":"119","article-title":"Automated real time integration of data from multiple sensors and non-sensor systems for prediction of dairy cow and herd status and performance","volume":"103","author":"Perez","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib31","doi-asserted-by":"crossref","first-page":"10560","DOI":"10.3168\/jds.2019-17951","article-title":"Early-lactation diseases and fertility in 2 seasons of calving across US dairy herds","volume":"103","author":"Pinedo","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib32","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.3168\/jds.2018-15386","article-title":"Associations of pre- and postpartum lying time with metabolic, inflammation, and health status of lactating dairy cows","volume":"102","author":"Pi\u00f1eiro","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib33","doi-asserted-by":"crossref","first-page":"9419","DOI":"10.3168\/jds.2018-14422","article-title":"Association between metabolic diseases and the culling risk of high-yielding dairy cows in a transition management facility using survival and decision tree analysis","volume":"101","author":"Probo","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib34","unstructured":"Radostits, O. M., C. Gay, K. W. Hinchcliff, and P. D. Constable. 2006. Veterinary Medicine E-Book: A textbook of the diseases of cattle, horses, sheep, pigs and goats."},{"key":"10.3168\/jds.2022-23156_bib35","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.3168\/jds.2017-12686","article-title":"Evaluation of an ear-tag-based accelerometer for monitoring rumination in dairy cows","volume":"101","author":"Reiter","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib36","doi-asserted-by":"crossref","first-page":"9345","DOI":"10.3168\/jds.2022-23157","article-title":"Metritis and clinical mastitis events in lactating dairy cows were associated with altered patterns of rumination, physical activity, and lying behavior monitored by an ear-attached sensor","volume":"106","author":"Rial","year":"2023","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib37","doi-asserted-by":"crossref","first-page":"5682","DOI":"10.3168\/jds.2012-6335","article-title":"Prevalence of periparturient diseases and effects on fertility of seasonally calving grazing dairy cows supplemented with concentrates","volume":"96","author":"Ribeiro","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib38","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.3168\/jds.2012-6107","article-title":"Invited review: sensors to support health management on dairy farms","volume":"96","author":"Rutten","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib39","doi-asserted-by":"crossref","first-page":"6222","DOI":"10.3168\/jds.2020-19667","article-title":"Evaluation and characterization of estrus alerts and behavioral parameters generated by an ear-attached accelerometer-based system for automated detection of estrus","volume":"104","author":"Schilkowsky","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib40","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.3168\/jds.2020-18562","article-title":"Effects of adding an automated monitoring device to the health screening of postpartum Holstein cows on survival and productive and reproductive performances","volume":"104","author":"Silva","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib41","doi-asserted-by":"crossref","first-page":"4544","DOI":"10.2527\/jas.2011-5064","article-title":"Relationships between rumination time, metabolic conditions, and health status in dairy cows during the transition period","volume":"90","author":"Soriani","year":"2012","journal-title":"J. Anim. Sci."},{"key":"10.3168\/jds.2022-23156_bib42","doi-asserted-by":"crossref","first-page":"7395","DOI":"10.3168\/jds.2016-10907","article-title":"Use of rumination and activity monitoring for the identification of dairy cows with health disorders: Part I. Metabolic and digestive disorders","volume":"99","author":"Stangaferro","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib43","doi-asserted-by":"crossref","first-page":"7411","DOI":"10.3168\/jds.2016-10908","article-title":"Use of rumination and activity monitoring for the identification of dairy cows with health disorders: Part II. Mastitis","volume":"99","author":"Stangaferro","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib44","doi-asserted-by":"crossref","first-page":"7422","DOI":"10.3168\/jds.2016-11352","article-title":"Use of rumination and activity monitoring for the identification of dairy cows with health disorders: Part III. Metritis","volume":"99","author":"Stangaferro","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib45","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.3168\/jds.2010-3295","article-title":"Blood profiles in dairy cows with displaced abomasum","volume":"93","author":"Steng\u00e4rde","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib46","doi-asserted-by":"crossref","first-page":"9573","DOI":"10.3168\/jds.2020-18636","article-title":"Transition dairy cow health is associated with first postpartum ovulation risk, metabolic status, milk production, rumination, and physical activity","volume":"103","author":"Stevenson","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2022-23156_bib47","unstructured":"USDA. 2018. Dairy 2014: Health and Management Practices on U.S. Dairy Operations, 2014. USDA-APHIS-VS-CEAH-NAHMS, Fort Collins, CO, 80526\u20138117, #696.0218."},{"key":"10.3168\/jds.2022-23156_bib48","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1017\/S1751731118001842","article-title":"Relationship between metabolic status and behavior in dairy cows in week 4 of lactation","volume":"13","author":"van Hoeij","year":"2019","journal-title":"Animal"},{"key":"10.3168\/jds.2022-23156_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.compag.2020.105233","article-title":"Machine learning to detect behavioural anomalies in dairy cows under subacute ruminal acidosis","volume":"170","author":"Wagner","year":"2020","journal-title":"Comput. Electron. Agric."},{"key":"10.3168\/jds.2022-23156_bib50","article-title":"The early prediction of common disorders in dairy cows monitored by automatic systems with machine learning algorithms","volume":"12","author":"Zhou","year":"2022","journal-title":"Animals (Basel)"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223005532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030223005532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223005532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T19:32:47Z","timestamp":1762198367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030223005532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0022030223005532"],"URL":"https:\/\/doi.org\/10.3168\/jds.2022-23156","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolic-digestive clinical disorders of lactating dairy cows were associated with alterations of rumination, physical activity, and lying behavior monitored by an ear-attached sensor","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2022-23156","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.3168\/jds.2022-23157","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s).","name":"copyright","label":"Copyright"}]}}