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Proc."},{"key":"10.3168\/jds.2023-24488_bib69","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/bies.201300084","article-title":"The Warburg effect then and now: From cancer to inflammatory diseases","volume":"35","author":"Palsson-McDermott","year":"2013","journal-title":"BioEssays"},{"key":"10.3168\/jds.2023-24488_bib70","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3168\/jds.S0022-0302(86)80390-3","article-title":"Effect of season and stage of lactation on performance of Holsteins","volume":"69","author":"Perera","year":"1986","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib71","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1189\/jlb.1209793","article-title":"Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxin","volume":"88","author":"Pillay","year":"2010","journal-title":"J. Leukoc. Biol."},{"key":"10.3168\/jds.2023-24488_bib72","doi-asserted-by":"crossref","first-page":"5347","DOI":"10.3168\/jds.2018-15446","article-title":"Undernutrition modified metabolic responses to intramammary lipopolysaccharide but had limited effects on selected inflammation indicators in early-lactation cows","volume":"102","author":"Pires","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib73","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3168\/jds.S0022-0302(73)85300-7","article-title":"Lipid characterization of bovine serum lipoproteins throughout gestation and lactation","volume":"56","author":"Raphael","year":"1973","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib74","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/jn\/124.6.906","article-title":"Do the differences between the amino acid compositions of acute-phase and muscle proteins have a bearing on nitrogen loss in traumatic states?","volume":"124","author":"Reeds","year":"1994","journal-title":"J. Nutr."},{"key":"10.3168\/jds.2023-24488_bib75","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/nri2711","article-title":"The regulation of IL-10 production by immune cells","volume":"10","author":"Saraiva","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.3168\/jds.2023-24488_bib76","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.2460\/ajvr.1996.57.11.1569","article-title":"Bacterial growth, inflammatory cytokine production, and neutrophil recruitment during coliform mastitis in cows within ten days after calving, compared with cows at midlactation","volume":"57","author":"Shuster","year":"1996","journal-title":"Am. J. Vet. Res."},{"key":"10.3168\/jds.2023-24488_bib77","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1210\/er.2017-00211","article-title":"Metabolic flexibility as an adaptation to energy resources and requirements in health and disease","volume":"39","author":"Smith","year":"2018","journal-title":"Endocr. Rev."},{"key":"10.3168\/jds.2023-24488_bib78","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0165-2427(95)05465-0","article-title":"Enhanced production of bovine tumor necrosis factor-\u03b1 during the periparturient period","volume":"49","author":"Sordillo","year":"1995","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2023-24488_bib79","series-title":"Fundamentals of Veterinary Clinical Pathology","first-page":"70","author":"Stockham","year":"2008"},{"key":"10.3168\/jds.2023-24488_bib80","article-title":"Dynamic changes in amino acid concentration profiles in patients with sepsis","volume":"10","author":"Su","year":"2015","journal-title":"PLoS One"},{"key":"10.3168\/jds.2023-24488_bib81","doi-asserted-by":"crossref","first-page":"8561","DOI":"10.3168\/jds.2023-23259","article-title":"Effects of dietary rumen-protected choline supplementation to periparturient dairy cattle on inflammation, metabolism, and performance during an intramammary lipopolysaccharide challenge","volume":"106","author":"Swartz","year":"2023","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib82","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.cbpc.2003.09.004","article-title":"Distribution of apolipoprotein E among lipoprotein fractions in the lactating cow","volume":"136","author":"Takahashi","year":"2003","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.3168\/jds.2023-24488_bib83","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1152\/ajplegacy.1963.205.6.1113","article-title":"Inhibition of gastric emptying in mice by bacterial endotoxins","volume":"205","author":"Turner","year":"1963","journal-title":"Am. J. Physiol."},{"key":"10.3168\/jds.2023-24488_bib84","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1079\/PNS19920053","article-title":"Effects of diet on lipolysis and its regulation","volume":"51","author":"Vernon","year":"1992","journal-title":"Proc. Nutr. Soc."},{"key":"10.3168\/jds.2023-24488_bib85","doi-asserted-by":"crossref","first-page":"596","DOI":"10.3168\/jds.S0022-0302(06)72123-3","article-title":"Acute experimental mastitis is not causal toward the development of energy-related metabolic disorders in early postpartum dairy cows","volume":"89","author":"Waldron","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib86","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.3168\/jds.S0022-0302(03)73949-6","article-title":"Effect of lipopolysaccharide on indices of peripheral and hepatic metabolism in lactating cows","volume":"86","author":"Waldron","year":"2003","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2023-24488_bib87","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1515\/znb-1958-0806","article-title":"Stoffwechsel der wei\u00dfen Blutzellen","volume":"13","author":"Warburg","year":"1958","journal-title":"Z. Naturforsch. B. J. Chem. Sci."},{"key":"10.3168\/jds.2023-24488_bib88","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10112412","article-title":"Metabolic alterations in sepsis","volume":"10","author":"Wasyluk","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.3168\/jds.2023-24488_bib89","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1161\/01.ATV.12.3.341","article-title":"Low density lipoproteins inhibit endotoxin activation of monocytes","volume":"12","author":"Weinstock","year":"1992","journal-title":"Arterioscler. Thromb."},{"key":"10.3168\/jds.2023-24488_bib90","doi-asserted-by":"crossref","first-page":"5230","DOI":"10.1210\/en.2007-0394","article-title":"Evidence that lipopolysaccharide-induced anorexia depends upon central, rather than peripheral, inflammatory signals","volume":"148","author":"Wisse","year":"2007","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2023-24488_bib91","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/emph\/eoaa044","article-title":"Let fever do its job: The meaning of fever in the pandemic era","volume":"9","author":"Wrotek","year":"2021","journal-title":"Evol. Med. Public Health"},{"key":"10.3168\/jds.2023-24488_bib92","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0165-2427(97)00030-5","article-title":"Primary culture and expression of cytokine mRNAs by lipopolysaccharide in bovine Kupffer cells","volume":"58","author":"Yoshioka","year":"1997","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2023-24488_bib93","doi-asserted-by":"crossref","first-page":"R1096","DOI":"10.1152\/ajpregu.00404.2017","article-title":"Heat stress decreases metabolic flexibility in skeletal muscle of growing pigs","volume":"315","author":"Zhao","year":"2018","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.3168\/jds.2023-24488_bib94","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1172\/JCI114857","article-title":"Skeletal muscle metabolism is a major determinant of resting energy expenditure","volume":"86","author":"Zurlo","year":"1990","journal-title":"J. Clin. 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