{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T09:42:34Z","timestamp":1747215754629,"version":"3.40.5"},"reference-count":45,"publisher":"American Dairy Science Association","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.3168\/jds.2024-25443","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T06:30:07Z","timestamp":1732602607000},"page":"2914-2932","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of gonadorelin dose and an additional gonadorelin treatment 2 days after the initiation of Resynch-25 on ovarian dynamics and fertility of lactating Holstein cows"],"prefix":"10.3168","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7017-3642","authenticated-orcid":false,"given":"Iago M.R.","family":"Le\u00e3o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4781-2466","authenticated-orcid":false,"given":"Carlos E.C.","family":"Consentini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2589-0965","authenticated-orcid":false,"given":"Marcelo S.","family":"El Azzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5528-5582","authenticated-orcid":false,"given":"Everaldo","family":"Anta-Galv\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5187-5905","authenticated-orcid":false,"given":"Teresita","family":"Vald\u00e9s-Arciniega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8394-2583","authenticated-orcid":false,"given":"Lucas","family":"Oliveira e Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6917-0057","authenticated-orcid":false,"given":"Roberto","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0452-3207","authenticated-orcid":false,"given":"Jo\u00e3o Paulo N.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2024-25443_bib1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.theriogenology.2016.09.055","article-title":"Proposal of a new model for CL regression or maintenance during pregnancy on the basis of timing of regression of contralateral, accessory CL in pregnant cows","volume":"89","author":"Baez","year":"2017","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib2","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.3168\/jds.S0022-0302(06)72378-5","article-title":"Optimizing ovulation to first GnRH improved outcomes to each hormonal injection of Ovsynch in lactating dairy cows","volume":"89","author":"Bello","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib3","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.3168\/jds.2012-6038","article-title":"Targeted progesterone supplementation improves fertility in lactating dairy cows without a corpus luteum at the initiation of the timed artificial insemination protocol","volume":"96","author":"Bisinotto","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib4","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.3168\/jds.2014-9058","article-title":"Progesterone supplementation to lactating dairy cows without a corpus luteum at initiation of the Ovsynch protocol","volume":"98","author":"Bisinotto","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib5","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.3168\/jds.2010-3047","article-title":"Follicular wave of the ovulatory follicle and not cyclic status influences fertility of dairy cows","volume":"93","author":"Bisinotto","year":"2010","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib6","doi-asserted-by":"crossref","first-page":"8290","DOI":"10.3168\/jds.2021-20274","article-title":"Replacing the first gonadotropin-releasing hormone treatment in an Ovsynch protocol with human chorionic gonadotropin decreased pregnancies per artificial insemination in lactating dairy cows","volume":"104","author":"Cabrera","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib7","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1530\/REP-08-0242","article-title":"Period of dominance of the ovulatory follicle influences embryo quality in lactating dairy cows","volume":"137","author":"Cerri","year":"2009","journal-title":"Reproduction"},{"key":"10.3168\/jds.2024-25443_bib8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.domaniend.2006.11.004","article-title":"Effects of plasma progesterone concentrations on LH release and ovulation in beef cattle given GnRH","volume":"34","author":"Colazo","year":"2008","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.3168\/jds.2024-25443_bib9","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.3168\/jds.2021-20619","article-title":"Accessory corpus luteum induced by human chorionic gonadotropin on day 7 or days 7 and 13 of the estrous cycle affected follicular and luteal dynamics and luteolysis in lactating Holstein cows","volume":"105","author":"Cunha","year":"2022","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib10","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.3168\/jds.2011-4214","article-title":"Effects of sex-sorting and sperm dosage on conception rates of Holstein heifers: Is comparable fertility of sex-sorted and conventional semen plausible?","volume":"94","author":"DeJarnette","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib11","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.3168\/jds.2011-4650","article-title":"Low progesterone concentration during the development of the first follicular wave reduces pregnancy per insemination of lactating dairy cows","volume":"95","author":"Denicol","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib12","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3168\/jdsc.2022-0220","article-title":"Effects of human chorionic gonadotropin on the last day of a 5-day CIDR Synch protocol and 5 days later on circulating progesterone concentrations and luteal area in Holstein heifers","volume":"3","author":"El Azzi","year":"2022","journal-title":"JDS Commun."},{"key":"10.3168\/jds.2024-25443_bib13","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"Faul","year":"2007","journal-title":"Behav. Res. Methods"},{"key":"10.3168\/jds.2024-25443_bib14","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.3168\/jds.2012-5982","article-title":"Economic comparison of reproductive programs for dairy herds using estrus detection, timed artificial insemination, or a combination","volume":"96","author":"Galv\u00e3o","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib15","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.3168\/jds.2007-0182","article-title":"Reducing the interval from presynchronization to initiation of timed artificial insemination improves fertility in dairy cows","volume":"90","author":"Galv\u00e3o","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib16","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.3168\/jds.2011-5155","article-title":"Effect of progesterone on magnitude of the luteinizing hormone surge induced by two different doses of gonadotropin-releasing hormone in lactating dairy cows","volume":"95","author":"Giordano","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib17","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.3168\/jds.2015-10223","article-title":"Reproductive management strategies to improve the fertility of cows with a suboptimal response to resynchronization of ovulation","volume":"99","author":"Giordano","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib18","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.theriogenology.2013.07.003","article-title":"Effect of increasing GnRH and PGF2\u03b1 dose during Double-Ovsynch on ovulatory response, luteal regression, and fertility of lactating dairy cows","volume":"80","author":"Giordano","year":"2013","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib19","doi-asserted-by":"crossref","first-page":"5612","DOI":"10.3168\/jds.2011-5035","article-title":"Effect of presynchronization with human chorionic gonadotropin or gonadotropin-releasing hormone 7 days before resynchronization of ovulation on fertility in lactating dairy cows","volume":"95","author":"Giordano","year":"2012","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib20","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.3168\/jds.S0022-0302(03)73921-6","article-title":"Follicular size and response to Ovsynch versus detection of estrus in anovular and ovular lactating dairy cows","volume":"86","author":"G\u00fcmen","year":"2003","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib21","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3168\/jdsc.2023-0540","article-title":"Effect of an additional GnRH two days after the initiation of a resynchronization program 25 days after artificial insemination on fertility of lactating dairy cows","volume":"5","author":"Le\u00e3o","year":"2024","journal-title":"JDS Commun."},{"key":"10.3168\/jds.2024-25443_bib22","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.3168\/jds.2023-23938","article-title":"Effect of 200 \u00b5g of gonadorelin at the first gonadotropin-releasing hormone of the Resynch-25 on ovarian dynamics and fertility in lactating Holstein cows","volume":"107","author":"Le\u00e3o","year":"2024","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib23","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.3168\/jds.2012-6429","article-title":"Effect of timing of initiation of resynchronization and presynchronization with gonadotropin-releasing hormone on fertility of resynchronized inseminations in lactating dairy cows","volume":"96","author":"Lopes","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib24","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.3168\/jds.2022-22651","article-title":"Presynchronization with prostaglandin F2\u03b1 and gonadotropin-releasing hormone simultaneously improved first-service pregnancy per artificial insemination in lactating Holstein cows compared with Presynch-14 when combined with detection of estrus","volume":"106","author":"Martins","year":"2023","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib25","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.theriogenology.2011.10.021","article-title":"Effects of resynchronization strategies for lactating Holstein cows on pattern of reinsemination, fertility, and economic outcome","volume":"77","author":"Mendon\u00e7a","year":"2012","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib26","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.theriogenology.2013.10.009","article-title":"Lack of complete regression of the day 5 corpus luteum after one or two doses of PGF2\u03b1 in nonlactating Holstein cows","volume":"81","author":"Nascimento","year":"2014","journal-title":"Theriogenology"},{"year":"2001","series-title":"Nutrient Requirements of Dairy Cattle. 7th rev. ed","author":"NRC","key":"10.3168\/jds.2024-25443_bib27"},{"key":"10.3168\/jds.2024-25443_bib28","series-title":"Large Dairy Herd Management","first-page":"549","article-title":"Monitoring and quantifying the value of change in reproductive performance","author":"Overton","year":"2017"},{"key":"10.3168\/jds.2024-25443_bib29","series-title":"Veterinary Reproduction and Obstetrics","first-page":"393","article-title":"Infertility and subfertility in the cow: Structural and functional abnormalities, management deficiencies and non-specific infections","author":"Parkinson","year":"2009"},{"key":"10.3168\/jds.2024-25443_bib30","doi-asserted-by":"crossref","first-page":"10769","DOI":"10.3168\/jds.2020-18607","article-title":"Lactating dairy cows managed for second and greater artificial insemination services with the Short-Resynch or Day 25 Resynch program had similar reproductive performance","volume":"103","author":"P\u00e9rez","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib31","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0093-691X(95)00279-H","article-title":"Synchronization of ovulation in dairy cows using PGF2\u03b1, and GnRH","volume":"44","author":"Pursley","year":"1995","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib32","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1530\/jrf.0.1060039","article-title":"Prolonged dominance of follicles and reduced viability of bovine oocytes","volume":"106","author":"Revah","year":"1996","journal-title":"Reproduction"},{"key":"10.3168\/jds.2024-25443_bib33","doi-asserted-by":"crossref","first-page":"9851","DOI":"10.3168\/jds.2017-13293","article-title":"Characterization of luteal dynamics in lactating Holstein cows for 32 days after synchronization of ovulation and timed artificial insemination","volume":"100","author":"Ricci","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib34","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.theriogenology.2019.09.013","article-title":"A shortened resynchronization treatment for dairy cows after a nonpregnancy diagnosis","volume":"141","author":"Sauls-Hiesterman","year":"2020","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib35","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.3168\/jds.2008-1704","article-title":"Effect of interval to resynchronization of ovulation on fertility of lactating Holstein cows when using mtransrectal ultrasonography or a pregnancy-associated glycoprotein enzyme-linked immunosorbent assay to diagnose pregnancy status","volume":"92","author":"Silva","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib36","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.theriogenology.2008.03.014","article-title":"A new presynchronization system (Double-Ovsynch) increases fertility at first postpartum timed AI in lactating dairy cows","volume":"70","author":"Souza","year":"2008","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib37","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.theriogenology.2009.02.016","article-title":"Comparison of gonadorelin products in lactating dairy cows: Efficacy based on induction of ovulation of an accessory follicle and circulating luteinizing hormone profiles","volume":"72","author":"Souza","year":"2009","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib38","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.3168\/jds.S0022-0302(06)72280-9","article-title":"Effect of interval from timed artificial insemination to initiation of resynchronization of ovulation on fertility of lactating dairy cows","volume":"89","author":"Sterry","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib39","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.3168\/jds.S0022-0302(06)72333-5","article-title":"Treatment of cycling and noncycling lactating dairy cows with progesterone during Ovsynch","volume":"89","author":"Stevenson","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib40","doi-asserted-by":"crossref","first-page":"9718","DOI":"10.3168\/jds.2023-23416","article-title":"Effect of using 200 \u00b5g of gonadorelin at the first GnRH of the breeding-Ovsynch on ovulatory response and pregnancies per AI in first service lactating Holstein cows","volume":"106","author":"Vald\u00e9s-Arciniega","year":"2023","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib41","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/S0093-691X(99)00195-8","article-title":"Synchronization rate, size of the ovulatory follicle, and pregnancy rate after synchronization of ovulation beginning on different days of the estrous cycle in lactating dairy cows","volume":"52","author":"Vasconcelos","year":"1999","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2024-25443_bib42","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.3168\/jds.2017-13489","article-title":"A resynchronization of ovulation program based on ovarian structures present at nonpregnancy diagnosis reduced time to pregnancy in lactating dairy cows","volume":"101","author":"Wijma","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib43","doi-asserted-by":"crossref","first-page":"7613","DOI":"10.3168\/jds.2017-12550","article-title":"Resynchronization of ovulation protocols for dairy cows including or not including gonadotropin-releasing hormone to induce a new follicular wave: Effects on re-insemination pattern, ovarian responses, and pregnancy outcomes","volume":"100","author":"Wijma","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib44","doi-asserted-by":"crossref","first-page":"8644","DOI":"10.3168\/jds.2015-9353","article-title":"Effect of a second treatment with prostaglandin F2\u03b1 during the Ovsynch protocol on luteolysis and pregnancy in dairy cows","volume":"98","author":"Wiltbank","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2024-25443_bib45","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1095\/biolreprod53.4.951","article-title":"Expression of follicle-stimulating hormone and luteinizing hormone receptor messenger ribonucleic acids in bovine follicles during the first follicular wave","volume":"53","author":"Xu","year":"1995","journal-title":"Biol. Reprod."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002203022401333X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002203022401333X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T00:22:31Z","timestamp":1741479751000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002203022401333X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S002203022401333X"],"URL":"https:\/\/doi.org\/10.3168\/jds.2024-25443","relation":{},"ISSN":["0022-0302"],"issn-type":[{"type":"print","value":"0022-0302"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of gonadorelin dose and an additional gonadorelin treatment 2 days after the initiation of Resynch-25 on ovarian dynamics and fertility of lactating Holstein cows","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2024-25443","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s).","name":"copyright","label":"Copyright"}]}}