{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T06:20:37Z","timestamp":1778394037592,"version":"3.51.4"},"reference-count":61,"publisher":"American Dairy Science Association","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007709","name":"Michigan State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007709","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.3168\/jds.2025-26951","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T04:11:28Z","timestamp":1758255088000},"page":"1219-1233","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Abomasal infusion of docosahexaenoic acid to mid-lactation cows alters circulating leukocyte profiles and affects immune response to ex vivo bacterial stimulation"],"prefix":"10.3168","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5330-6765","authenticated-orcid":false,"given":"H.L.","family":"Reisinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8075-2774","authenticated-orcid":false,"given":"M.L.","family":"Hoorman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9809-0611","authenticated-orcid":false,"given":"K.C.","family":"Krogstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3612-0381","authenticated-orcid":false,"given":"L.K.","family":"Mamedova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0252-2673","authenticated-orcid":false,"given":"D.","family":"Vocelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4969-2178","authenticated-orcid":false,"given":"G.A.","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9282-399X","authenticated-orcid":false,"given":"A.L.","family":"Lock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6775-4961","authenticated-orcid":false,"given":"B.J.","family":"Bradford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2025-26951_bib1","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.3168\/jds.S0022-0302(02)74306-3","article-title":"Fatty acid profiles of milk and rumen digesta from cows fed fish oil, extruded soybeans or their blend","volume":"85","author":"AbuGhazaleh","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib2","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3945\/ajcn.116.131896","article-title":"A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: The Comparing EPA to DHA (ComparED) Study","volume":"104","author":"Allaire","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"10.3168\/jds.2025-26951_bib3","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/1074-7613(94)90076-0","article-title":"Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice","volume":"1","author":"Arbon\u00e9s","year":"1994","journal-title":"Immunity"},{"key":"10.3168\/jds.2025-26951_bib4","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1538-7836.2011.04193.x","article-title":"Efficient phagocytosis of periodontopathogens by neutrophils requires plasma factors, platelets and TLR2","volume":"9","author":"Assinger","year":"2011","journal-title":"J. Thromb. Haemost."},{"key":"10.3168\/jds.2025-26951_bib5","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1039\/C9FO02618E","article-title":"The immunomodulatory effect of docosahexaenoic acid (DHA) on the RAW264.7 cells by modification of the membrane structure and function","volume":"11","author":"Bie","year":"2020","journal-title":"Food Funct."},{"key":"10.3168\/jds.2025-26951_bib6","doi-asserted-by":"crossref","first-page":"3386","DOI":"10.3168\/jds.S0022-0302(06)72375-X","article-title":"Pregnancy, bovine somatotropin, and dietary n-3 fatty acids in lactating dairy cows: III. Fatty acid distribution","volume":"89","author":"Bilby","year":"2006","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.rvsc.2017.03.012","article-title":"Immunological implications of bovine leukemia virus infection","volume":"114","author":"Blagitz","year":"2017","journal-title":"Res. Vet. Sci."},{"key":"10.3168\/jds.2025-26951_bib8","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/y59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Physiol."},{"key":"10.3168\/jds.2025-26951_bib9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/imr.12693","article-title":"Current best estimates for the average lifespans of mouse and human leukocytes: Reviewing two decades of deuterium-labeling experiments","volume":"285","author":"Borghans","year":"2018","journal-title":"Immunol. Rev."},{"key":"10.3168\/jds.2025-26951_bib10","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3945\/ajcn.112.041343","article-title":"Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish","volume":"96","author":"Browning","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"10.3168\/jds.2025-26951_bib11","doi-asserted-by":"crossref","first-page":"592S","DOI":"10.3945\/jn.111.155259","article-title":"Mechanisms of action of (n-3) fatty acids","volume":"142","author":"Calder","year":"2012","journal-title":"J. Nutr."},{"key":"10.3168\/jds.2025-26951_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115211","article-title":"Omega-3 polyunsaturated fatty acids reverse the impact of western diets on regulatory T cell responses through averting ceramide-mediated pathways","volume":"204","author":"Camacho-Mu\u00f1oz","year":"2022","journal-title":"Biochem. Pharmacol."},{"key":"10.3168\/jds.2025-26951_bib13","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1182\/blood.V24.6.780.780","article-title":"Analytical review: The kinetics of granulopoiesis in normal man","volume":"24","author":"Cartwright","year":"1964","journal-title":"Blood"},{"key":"10.3168\/jds.2025-26951_bib14","doi-asserted-by":"crossref","first-page":"4149","DOI":"10.3168\/jds.2006-856","article-title":"Effect of supplementation with calcium salts of fish oil on n-3 fatty acids in milk fat","volume":"90","author":"Casta\u00f1eda-Guti\u00e9rrez","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib15","series-title":"Preparation of Ester Derivatives of Fatty Acids for Chromatographic Analysis\u2014Two","author":"Christie","year":"1993"},{"key":"10.3168\/jds.2025-26951_bib16","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.immuni.2014.02.014","article-title":"Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis","volume":"40","author":"Chu","year":"2014","journal-title":"Immunity"},{"key":"10.3168\/jds.2025-26951_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-07455-2","article-title":"Optimization of methods for the accurate characterization of whole blood neutrophils","volume":"12","author":"Connelly","year":"2022","journal-title":"Sci. Rep."},{"key":"10.3168\/jds.2025-26951_bib18","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1172\/JCI108517","article-title":"Neutrophil kinetics in man","volume":"58","author":"Dancey","year":"1976","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2025-26951_bib19","doi-asserted-by":"crossref","first-page":"7996","DOI":"10.3168\/jds.2024-24907","article-title":"Long-term effects of abomasal infusion of linoleic and linolenic acids on the enrichment of n-6 and n-3 fatty acids into plasma lipid fractions of lactating cows","volume":"107","author":"dos Santos Neto","year":"2024","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib20","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1093\/jn\/133.6.1913","article-title":"Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts","volume":"133","author":"Fan","year":"2003","journal-title":"J. Nutr."},{"key":"10.3168\/jds.2025-26951_bib21","doi-asserted-by":"crossref","first-page":"5803","DOI":"10.1128\/IAI.71.10.5803-5813.2003","article-title":"Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria","volume":"71","author":"Feezor","year":"2003","journal-title":"Infect. Immun."},{"key":"10.3168\/jds.2025-26951_bib22","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/jn\/nxaa294","article-title":"Time course and sex effects of \u03b1-linolenic acid-rich and DHA-rich supplements on human plasma oxylipins: A randomized double-blind crossover trial","volume":"151","author":"Gabbs","year":"2021","journal-title":"J. Nutr."},{"key":"10.3168\/jds.2025-26951_bib23","doi-asserted-by":"crossref","first-page":"4590","DOI":"10.3168\/jds.2015-9974","article-title":"Effects of whole flaxseed, raw soybeans, and calcium salts of fatty acids on measures of cellular immune function of transition dairy cows","volume":"99","author":"Gandra","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.02448","article-title":"Choline regulates the function of bovine immune cells and alters the mRNA abundance of enzymes and receptors involved in its metabolism in vitro.","volume":"9","author":"Garcia","year":"2018","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-26951_bib25","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3168\/jds.2014-8805","article-title":"Effects of altering the ratio of dietary n-6 to n-3 fatty acids on performance and inflammatory responses to a lipopolysaccharide challenge in lactating Holstein cows","volume":"98","author":"Greco","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib26","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.smim.2014.05.004","article-title":"Regulation of NF-\u03baB by TNF family cytokines","volume":"26","author":"Hayden","year":"2014","journal-title":"Semin. Immunol."},{"key":"10.3168\/jds.2025-26951_bib27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.rvsc.2016.12.011","article-title":"Docosahexaenoic acid attenuates LPS-stimulated inflammatory response by regulating the PPAR\u03b3\/NF-\u03baB pathways in primary bovine mammary epithelial cells","volume":"112","author":"He","year":"2017","journal-title":"Res. Vet. Sci."},{"key":"10.3168\/jds.2025-26951_bib28","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1111\/j.1432-1033.1993.tb18328.x","article-title":"Dihydrorhodamine 123: A fluorescent probe for superoxide generation?","volume":"217","author":"Henderson","year":"1993","journal-title":"Eur. J. Biochem."},{"key":"10.3168\/jds.2025-26951_bib29","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1021\/es00082a001","article-title":"Less than obvious\u2014Statistical treatment of data below the detection limit","volume":"24","author":"Helsel","year":"1990","journal-title":"Environ. Sci. Technol."},{"key":"10.3168\/jds.2025-26951_bib30","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cyto.2004.05.008","article-title":"Gram-positive and gram-negative bacteria elicit different patterns of pro-inflammatory cytokines in human monocytes","volume":"30","author":"Hessle","year":"2005","journal-title":"Cytokine"},{"key":"10.3168\/jds.2025-26951_bib31","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.3168\/jds.2025-26953","article-title":"Effect of abomasal infusions of docosahexaenoic acid on nutrient digestibility, plasma fatty acids, and production responses of mid-lactation dairy cows","volume":"109","author":"Hoorman","year":"2026","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib32","doi-asserted-by":"crossref","DOI":"10.1038\/srep11276","article-title":"A host-microbiome interaction mediates the opposing effects of omega-6 and omega-3 fatty acids on metabolic endotoxemia","volume":"5","author":"Kaliannan","year":"2015","journal-title":"Sci. Rep."},{"key":"10.3168\/jds.2025-26951_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jprot.2021.104313","article-title":"Proteomic analysis of peripheral blood mononuclear cells and inflammatory status in postpartum dairy cows supplemented with different sources of omega-3 fatty acids","volume":"246","author":"Kra","year":"2021","journal-title":"J. Proteomics"},{"key":"10.3168\/jds.2025-26951_bib34","doi-asserted-by":"crossref","first-page":"8508","DOI":"10.3168\/jds.2024-24974","article-title":"Effects of rumen-protected niacin on inflammatory response to repeated intramammary lipopolysaccharide challenges","volume":"107","author":"Krogstad","year":"2024","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib35","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1006\/cimm.1995.1174","article-title":"Loss of L-selectin (CD62L) on human neutrophils following exudation in vivo","volume":"164","author":"Kuhns","year":"1995","journal-title":"Cell. Immunol."},{"key":"10.3168\/jds.2025-26951_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/5831278","article-title":"Prevalence of bovine leukemia virus antibodies in US dairy cattle","volume":"2018","author":"LaDronka","year":"2018","journal-title":"Vet. Med. Int."},{"key":"10.3168\/jds.2025-26951_bib37","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.3168\/jds.2010-4046","article-title":"The selective treatment of clinical mastitis based on on-farm culture results: I. Effects on antibiotic use, milk withholding time, and short-term clinical and bacteriological outcomes","volume":"94","author":"Lago","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib38","doi-asserted-by":"crossref","first-page":"4812","DOI":"10.1074\/jbc.M609994200","article-title":"Mechanical shedding of L-selectin from the neutrophil surface during rolling on sialyl Lewis x under flow","volume":"282","author":"Lee","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2025-26951_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.871780","article-title":"Standardized whole blood assay and bead-based cytokine profiling reveal commonalities and diversity of the response to bacteria and TLR ligands in cattle","volume":"13","author":"Lesueur","year":"2022","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-26951_bib40","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1194\/jlr.M500033-JLR200","article-title":"Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts","volume":"46","author":"Li","year":"2005","journal-title":"J. Lipid Res."},{"key":"10.3168\/jds.2025-26951_bib41","doi-asserted-by":"crossref","first-page":"6650","DOI":"10.3168\/jds.2013-6892","article-title":"Feeding a C16:0-enriched fat supplement increased the yield of milk fat and improved conversion of feed to milk","volume":"96","author":"Lock","year":"2013","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119715","article-title":"Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1\/GPR40) in neutrophils","volume":"10","author":"Manosalva","year":"2015","journal-title":"PLoS One"},{"key":"10.3168\/jds.2025-26951_bib43","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.jnutbio.2009.02.008","article-title":"Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages","volume":"21","author":"Mullen","year":"2010","journal-title":"J. Nutr. Biochem."},{"key":"10.3168\/jds.2025-26951_bib44","series-title":"Nutrient Requirements of Dairy Cattle","author":"NASEM (National Academies of Sciences, Engineering, and Medicine)","year":"2021"},{"key":"10.3168\/jds.2025-26951_bib45","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nri3084","article-title":"Towards a systems understanding of MHC class I and MHC class II antigen presentation","volume":"11","author":"Neefjes","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.3168\/jds.2025-26951_bib46","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.cell.2010.07.041","article-title":"GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects","volume":"142","author":"Oh","year":"2010","journal-title":"Cell"},{"key":"10.3168\/jds.2025-26951_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210744","article-title":"Dietary supplementation of Scutellaria baicalensis extract during early lactation decreases milk somatic cells and increases whole lactation milk yield in dairy cattle","volume":"14","author":"Olagaray","year":"2019","journal-title":"PLoS One"},{"key":"10.3168\/jds.2025-26951_bib48","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S0022-2275(20)31576-5","article-title":"Physiological compartmental analysis of \u03b1-linolenic acid metabolism in adult humans","volume":"42","author":"Pawlosky","year":"2001","journal-title":"J. Lipid Res."},{"key":"10.3168\/jds.2025-26951_bib49","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.vetimm.2009.03.018","article-title":"In vitro modulatory effect of \u03c9-3 polyunsaturated fatty acid (EPA and DHA) on phagocytosis and ROS production of goat neutrophils","volume":"131","author":"Pisani","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2025-26951_bib50","doi-asserted-by":"crossref","first-page":"12616","DOI":"10.3168\/jds.2021-20954","article-title":"Abomasal infusion of oleic acid increases fatty acid digestibility and plasma insulin of lactating dairy cows","volume":"104","author":"Prom","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib51","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.3168\/jds.2010-3999","article-title":"Metabolic effects of feeding ethanol or propanol to postpartum transition Holstein cows","volume":"94","author":"Raun","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib52","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.3168\/jds.2016-11599","article-title":"Supplementation of linoleic acid (C18:2n-6) or \u03b1-linolenic acid (C18:3n-3) changes microbial agonist-induced oxylipid biosynthesis","volume":"100","author":"Ryman","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib53","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/s41584-021-00639-6","article-title":"Insights into the biology and therapeutic implications of TNF and regulatory T cells","volume":"17","author":"Salomon","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.3168\/jds.2025-26951_bib54","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1099\/00221287-30-2-223","article-title":"The relationship between the nature of the cell wall and the Gram stain","volume":"30","author":"Salton","year":"1963","journal-title":"J. Gen. Microbiol."},{"key":"10.3168\/jds.2025-26951_bib55","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.3168\/jds.2010-3371","article-title":"Effects of differential supplementation of fatty acids during the peripartum and breeding periods of Holstein cows: II. Neutrophil fatty acids and function, and acute phase proteins","volume":"94","author":"Silvestre","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-26951_bib56","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/s41392-023-01471-y","article-title":"T cells in health and disease","volume":"8","author":"Sun","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.3168\/jds.2025-26951_bib57","article-title":"The blood immune cell count, immunoglobulin, inflammatory factor, and milk trace element in transition cows and calves were altered by increasing the dietary n-3 or n-6 polyunsaturated fatty acid levels","volume":"13","author":"Sun","year":"2022","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-26951_bib58","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1074-7613(00)80119-3","article-title":"Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components","volume":"11","author":"Takeuchi","year":"1999","journal-title":"Immunity"},{"key":"10.3168\/jds.2025-26951_bib59","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1172\/JCI117788","article-title":"Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes","volume":"95","author":"Taub","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.3168\/jds.2025-26951_bib60","doi-asserted-by":"crossref","first-page":"22152","DOI":"10.1074\/jbc.M110.119867","article-title":"Structural basis of fatty acid substrate binding to cyclooxygenase-2","volume":"285","author":"Vecchio","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2025-26951_bib61","doi-asserted-by":"crossref","first-page":"22254","DOI":"10.1074\/jbc.M703169200","article-title":"Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products","volume":"282","author":"Wada","year":"2007","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030225007532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030225007532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T03:39:47Z","timestamp":1773977987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030225007532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0022030225007532"],"URL":"https:\/\/doi.org\/10.3168\/jds.2025-26951","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Abomasal infusion of docosahexaenoic acid to mid-lactation cows alters circulating leukocyte profiles and affects immune response to ex vivo bacterial stimulation","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2025-26951","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors.","name":"copyright","label":"Copyright"}]}}