{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:11:02Z","timestamp":1780650662433,"version":"3.54.1"},"reference-count":68,"publisher":"American Dairy Science Association","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010710","name":"Dairy Farmers of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010787","name":"Genome Alberta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015096","name":"Canadian Dairy Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015096","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000040","name":"Agriculture and Agri-Food Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000040","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008762","name":"Genome Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008762","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000233","name":"Genome British Columbia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000233","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.3168\/jds.2025-27026","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:35:15Z","timestamp":1760070915000},"page":"4170-4183","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genetic insights into bovine spastic syndrome (Crampy) in Holstein dairy cattle"],"prefix":"10.3168","volume":"109","author":[{"given":"Gabriella","family":"Condello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio S.","family":"Schenkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isis C.","family":"Hermisdorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M.","family":"Rochus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Van Doormaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Miglior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine F.","family":"Baes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2025-27026_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.794625","article-title":"Genetic modeling and genomic analyses of yearling temperament in American Angus cattle and its relationship with productive efficiency and resilience traits","volume":"13","author":"Alvarenga","year":"2022","journal-title":"Front. Genet."},{"key":"10.3168\/jds.2025-27026_bib2","doi-asserted-by":"crossref","first-page":"4999","DOI":"10.3168\/jds.2015-9371","article-title":"Short communication: Reliability of single-step genomic BLUP breeding values by multi-trait test-day model analysis","volume":"98","author":"Bauer","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib3","series-title":"Official Genetic Evaluation for Mastitis Resistance","author":"Beavers","year":"2013"},{"key":"10.3168\/jds.2025-27026_bib4","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3168\/jds.S0022-0302(61)89774-9","article-title":"Crampy or progressive posterior paralysis in mature cattle","volume":"44","author":"Becker","year":"1961","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib5","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/2046-0481-64-5","article-title":"Genetics of animal health and disease in cattle","volume":"64","author":"Berry","year":"2011","journal-title":"Ir. Vet. J."},{"key":"10.3168\/jds.2025-27026_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/genetics\/iyab141","article-title":"The quantitative genetics of the prevalence of infectious diseases: Hidden genetic variation due to indirect genetic effects dominates heritable variation and response to selection","volume":"220","author":"Bijma","year":"2022","journal-title":"Genetics"},{"key":"10.3168\/jds.2025-27026_bib7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3168\/jds.2024-25196","article-title":"Estimation of genetic parameters and genome-wide association study for enzootic bovine leukosis resistance in Canadian Holstein cattle","volume":"108","author":"Bongers","year":"2025","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib8","first-page":"100","article-title":"Spastic syndrome in two cows in Northeastern Brazil S\u00edndrome esp\u00e1stica em duas vacas no Nordeste Brasileiro","volume":"103","author":"C\u00e2mara","year":"2008","journal-title":"RPCV"},{"key":"10.3168\/jds.2025-27026_bib9","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1085\/jgp.53.4.414","article-title":"Role of calcium binding by sarcoplasmic reticulum in the contraction and relaxation of uterine smooth muscle","volume":"53","author":"Carsten","year":"1969","journal-title":"J. Gen. Physiol."},{"key":"10.3168\/jds.2025-27026_bib10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12711-016-0254-5","article-title":"Identification of selective sweeps reveals divergent selection between Chinese Holstein and Simmental cattle populations","volume":"48","author":"Chen","year":"2016","journal-title":"Genet. Sel. Evol."},{"key":"10.3168\/jds.2025-27026_bib11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/genetics\/35.2.212","article-title":"Heritability of threshold characters","volume":"35","author":"Dempster","year":"1950","journal-title":"Genetics"},{"key":"10.3168\/jds.2025-27026_bib12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/cercor\/bhs284","article-title":"Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase","volume":"24","author":"Di\u00f3genes","year":"2014","journal-title":"Cereb. Cortex"},{"key":"10.3168\/jds.2025-27026_bib13","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/d41573-020-00196-9","article-title":"WNK kinases: An untapped opportunity to modulate ion transport","volume":"19","author":"East","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.3168\/jds.2025-27026_bib14","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giaa149","article-title":"GALLO: An R package for genomic annotation and integration of multiple data sources in livestock for positional candidate loci","volume":"9","author":"Fonseca","year":"2020","journal-title":"Gigascience"},{"key":"10.3168\/jds.2025-27026_bib15","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/jbg.12115","article-title":"Genetic evaluation of calf and heifer survival in Iranian Holstein cattle using linear and threshold models","volume":"132","author":"Forutan","year":"2015","journal-title":"J. Anim. Breed. Genet."},{"key":"10.3168\/jds.2025-27026_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053173","article-title":"First WNK4-Hypokalemia animal model identified by genome-wide association in Burmese cats","volume":"7","author":"Gandolfi","year":"2012","journal-title":"PLoS One"},{"key":"10.3168\/jds.2025-27026_bib17","first-page":"17","article-title":"Inherited disorders of cattle: A selected review","volume":"43","author":"Gentile","year":"2006","journal-title":"Slov. Vet. Res."},{"key":"10.3168\/jds.2025-27026_bib18","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1439-0388.2011.00964.x","article-title":"Using the genomic relationship matrix to predict the accuracy of genomic selection","volume":"128","author":"Goddard","year":"2011","journal-title":"J. Anim. Breed. Genet."},{"key":"10.3168\/jds.2025-27026_bib19","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/vr.104814","article-title":"Bovine spastic syndrome: A review","volume":"182","author":"Goeckmann","year":"2018","journal-title":"Vet. Rec."},{"key":"10.3168\/jds.2025-27026_bib20","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/mp.2008.88","article-title":"The dystrobrevin-binding protein 1 gene: Features and networks","volume":"14","author":"Guo","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.3168\/jds.2025-27026_bib21","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.3168\/jds.2006-805","article-title":"Selection responses for disease resistance in two selection experiments with Norwegian Red cows","volume":"90","author":"Heringstad","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101529","article-title":"Zinc at the crossroads of exercise and proteostasis","volume":"35","author":"Hern\u00e1ndez-Camacho","year":"2020","journal-title":"Redox Biol."},{"key":"10.3168\/jds.2025-27026_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.animal.2024.101177","article-title":"Genetic analysis of health traits and their associations with longevity, fertility, production, and conformation traits in Holstein cattle","volume":"18","author":"Hu","year":"2024","journal-title":"Animal"},{"key":"10.3168\/jds.2025-27026_bib24","doi-asserted-by":"crossref","DOI":"10.1093\/genetics\/iyab024","article-title":"Why genetic selection to reduce the prevalence of infectious diseases is way more promising than currently believed","volume":"217","author":"Hulst","year":"2021","journal-title":"Genetics"},{"key":"10.3168\/jds.2025-27026_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-82446-z","article-title":"Whole genome sequencing reveals candidate causal genetic variants for spastic syndrome in Holstein cattle","volume":"14","author":"Jacinto","year":"2024","journal-title":"Sci. Rep."},{"key":"10.3168\/jds.2025-27026_bib26","first-page":"102","article-title":"Genomic evaluation for resistance to fertility disorders in Canadian dairy breeds","volume":"56","author":"Jamrozik","year":"2021","journal-title":"Interbull Bull."},{"key":"10.3168\/jds.2025-27026_bib27","first-page":"9","article-title":"Genetic evaluation for resistance to metabolic diseases in Canadian dairy breeds","volume":"50","author":"Jamrozik","year":"2016","journal-title":"Interbull Bull."},{"key":"10.3168\/jds.2025-27026_bib28","first-page":"43","article-title":"Genetic and genomic evaluation of mastitis resistance in Canada","volume":"47","author":"Jamrozik","year":"2013","journal-title":"Interbull Bull."},{"key":"10.3168\/jds.2025-27026_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2023.1168649","article-title":"Livestock health and disease economics: A scoping review of selected literature","volume":"10","author":"Kappes","year":"2023","journal-title":"Front. Vet. Sci."},{"key":"10.3168\/jds.2025-27026_bib30","unstructured":"Kolberg, L., and U. Raudvere. 2024. gprofiler2: Interface to the \u201cg:Profiler\u201d Toolset."},{"key":"10.3168\/jds.2025-27026_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2020.591794","article-title":"Frameshift variant in novel adenosine-A1-receptor homolog associated with bovine spastic syndrome\/late-onset bovine spastic paresis in Holstein sires","volume":"11","author":"Krull","year":"2020","journal-title":"Front. Genet."},{"key":"10.3168\/jds.2025-27026_bib32","doi-asserted-by":"crossref","first-page":"382","DOI":"10.5713\/ajas.19.0546","article-title":"The effectiveness of genomic selection for milk production traits of Holstein dairy cattle","volume":"33","author":"Lee","year":"2020","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"10.3168\/jds.2025-27026_bib33","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.3168\/jds.2009-2061","article-title":"A relationship matrix including full pedigree and genomic information","volume":"92","author":"Legarra","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib34","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12711-015-0137-1","article-title":"Accuracy of estimated breeding values with genomic information on males, females, or both: An example on broiler chicken","volume":"47","author":"Lourenco","year":"2015","journal-title":"Genet. Sel. Evol."},{"key":"10.3168\/jds.2025-27026_bib35","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.3168\/jds.2023-23780","article-title":"Investigating the potential for genetic selection of dairy calf disease traits using management data","volume":"107","author":"Lynch","year":"2024","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib36","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.3168\/jds.S0022-0302(91)78260-X","article-title":"Genetics of health traits in Holstein cattle","volume":"74","author":"Lyons","year":"1991","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib37","doi-asserted-by":"crossref","first-page":"5183","DOI":"10.3168\/jds.2019-18013","article-title":"Effect of genomic selection on rate of inbreeding and coancestry and effective population size of Holstein and Jersey cattle populations","volume":"103","author":"Makanjuola","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib38","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.3168\/jds.2019-17755","article-title":"Symposium review: Multiple-trait single-step genomic evaluation for hoof health","volume":"103","author":"Malchiodi","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib39","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1177\/1098612X15581135","article-title":"Periodic hypokalaemic polymyopathy in Burmese and closely related cats: A review including the latest genetic data","volume":"17","author":"Malik","year":"2015","journal-title":"J. Feline Med. Surg."},{"key":"10.3168\/jds.2025-27026_bib40","author":"Misztal"},{"key":"10.3168\/jds.2025-27026_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.585907","article-title":"Physiological processes modulated by the chloride-sensitive WNK-SPAK\/OSR1 kinase signaling pathway and the cation-coupled chloride cotransporters","volume":"11","author":"Murillo-de-Ozores","year":"2020","journal-title":"Front. Physiol."},{"key":"10.3168\/jds.2025-27026_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/genes14071479","article-title":"Investigating the genetic background of spastic syndrome in North American Holstein cattle based on heritability, genome-wide association, and functional genomic analyses","volume":"14","author":"Neustaeter","year":"2023","journal-title":"Genes (Basel)"},{"key":"10.3168\/jds.2025-27026_bib43","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nrg2813","article-title":"New approaches to population stratification in genome-wide association studies","volume":"11","author":"Price","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"10.3168\/jds.2025-27026_bib44","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1017\/S1751731112001401","article-title":"Genetic parameters for production, health, fertility and longevity traits in dairy cows","volume":"7","author":"Pritchard","year":"2013","journal-title":"Animal"},{"key":"10.3168\/jds.2025-27026_bib45","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: A tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.3168\/jds.2025-27026_bib46","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0737-0806(98)80409-7","article-title":"Genetic-diet interactions in the hyperkalemic periodic paralysis syndrome in quarter horses fed varying amounts of potassium: Part II-symptoms of HYPP","volume":"18","author":"Reynolds","year":"1998","journal-title":"J. Equine Vet. Sci."},{"key":"10.3168\/jds.2025-27026_bib47","author":"Richardson"},{"key":"10.3168\/jds.2025-27026_bib48","first-page":"380","article-title":"A spastic syndrome in dairy cattle","volume":"43","author":"Roberts","year":"1953","journal-title":"Cornell Veterinarian"},{"key":"10.3168\/jds.2025-27026_bib49","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1086\/419266","article-title":"The evolution of threshold traits in animals","volume":"71","author":"Roff","year":"1996","journal-title":"Q. Rev. Biol."},{"key":"10.3168\/jds.2025-27026_bib50","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1073\/pnas.1721508115","article-title":"Molecular mechanism of ATP versus GTP selectivity of adenylate kinase","volume":"115","author":"Rogne","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.3168\/jds.2025-27026_bib51","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giaa021","article-title":"De novo assembly of the cattle reference genome with single-molecule sequencing","volume":"9","author":"Rosen","year":"2020","journal-title":"Gigascience"},{"key":"10.3168\/jds.2025-27026_bib52","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4141\/A02-094","article-title":"Degree of connectedness among groups of centrally tested beef bulls","volume":"84","author":"Roso","year":"2004","journal-title":"Can. J. Anim. Sci."},{"key":"10.3168\/jds.2025-27026_bib53","series-title":"Proc. Cow Longevity Conference, Tumba, Sweden","first-page":"3","article-title":"The importance of improving cow longevity","author":"Rushen","year":"2013"},{"key":"10.3168\/jds.2025-27026_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.livsci.2020.104257","article-title":"Selection signatures in livestock genome: A review of concepts, approaches and applications","volume":"241","author":"Saravanan","year":"2020","journal-title":"Livest. Sci."},{"key":"10.3168\/jds.2025-27026_bib55","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.3168\/jds.2007-0553","article-title":"Extent of linkage disequilibrium in Holstein cattle in North America","volume":"91","author":"Sargolzaei","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib56","doi-asserted-by":"crossref","first-page":"4","DOI":"10.2527\/af.2011-0032","article-title":"Genomic selection in dairy cattle: Integration of DNA testing into breeding programs","volume":"2","author":"Schefers","year":"2012","journal-title":"Anim. Front."},{"key":"10.3168\/jds.2025-27026_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v021.i11","article-title":"boa: An R package for MCMC output convergence assessment and posterior inference","volume":"21","author":"Smith","year":"2007","journal-title":"J. Stat. Softw."},{"key":"10.3168\/jds.2025-27026_bib58","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0006-3495(75)85849-8","article-title":"Calcium regulation of muscle contraction","volume":"15","author":"Szent-Gy\u00f6rgyi","year":"1975","journal-title":"Biophys. J."},{"key":"10.3168\/jds.2025-27026_bib59","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/dvg.20255","article-title":"Conditional inactivation of the Cacna1a gene in transgenic mice","volume":"44","author":"Todorov","year":"2006","journal-title":"Genesis"},{"key":"10.3168\/jds.2025-27026_bib60","doi-asserted-by":"crossref","first-page":"7295","DOI":"10.3168\/jds.2017-12665","article-title":"Genomic analysis of cow mortality and milk production using a threshold-linear model","volume":"100","author":"Tsuruta","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib61","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/s43586-021-00056-9","article-title":"Genome-wide association studies","volume":"1","author":"Uffelmann","year":"2021","journal-title":"Nat. Rev. Methods Primers"},{"key":"10.3168\/jds.2025-27026_bib62","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF00220912","article-title":"Variance of prediction error with mixed model equations when relationships are ignored","volume":"85","author":"Van Vleck","year":"1993","journal-title":"Theor. Appl. Genet."},{"key":"10.3168\/jds.2025-27026_bib63","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3168\/jds.2008-1514","article-title":"Invited Review: Reliability of genomic predictions for North American Holstein bulls","volume":"92","author":"VanRaden","year":"2009","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib64","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.3168\/jds.2019-17821","article-title":"Association between serum calcium dynamics around parturition and common postpartum diseases in dairy cows","volume":"104","author":"Venjakob","year":"2021","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27026_bib65","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/030098588702400410","article-title":"Spastic syndrome in a Holstein bull: A histologic study","volume":"24","author":"Wells","year":"1987","journal-title":"Vet. Pathol."},{"key":"10.3168\/jds.2025-27026_bib66","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.994466","article-title":"Genomic selection in United States dairy cattle","volume":"13","author":"Wiggans","year":"2022","journal-title":"Front. Genet."},{"key":"10.3168\/jds.2025-27026_bib67","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ajhg.2010.11.011","article-title":"GCTA: A tool for genome-wide complex trait analysis","volume":"88","author":"Yang","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.3168\/jds.2025-27026_bib68","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3390\/dairy1010005","article-title":"Ketosis an old story under a new approach","volume":"1","author":"Zhang","year":"2020","journal-title":"Dairy"}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002203022500815X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002203022500815X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T08:53:16Z","timestamp":1780649596000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002203022500815X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":68,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S002203022500815X"],"URL":"https:\/\/doi.org\/10.3168\/jds.2025-27026","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic insights into bovine spastic syndrome (Crampy) in Holstein dairy cattle","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2025-27026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors.","name":"copyright","label":"Copyright"}]}}