{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:11:05Z","timestamp":1790626265037,"version":"4.1.0"},"reference-count":60,"publisher":"American Dairy Science Association","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["2010\/63"],"award-info":[{"award-number":["2010\/63"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.3168\/jds.2025-27163","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:14:17Z","timestamp":1769213657000},"page":"3158-3174","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bifidobacterium breve and lacto-N-neotetraose mediate gut microbiota-derived acetate to regulate defecation performance and intestinal barrier function in constipated mice"],"prefix":"10.3168","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2216-561X","authenticated-orcid":false,"given":"Yi","family":"Shan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfeng","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2025-27163_bib1","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s12223-022-00973-6","article-title":"Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome","volume":"67","author":"Aggarwal","year":"2022","journal-title":"Folia Microbiol. (Praha)"},{"key":"10.3168\/jds.2025-27163_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2021.111225","article-title":"A multiple-strain probiotic product provides a better enzymatic antioxidant response in individuals with constipation in a double-blind randomized controlled trial","volume":"89","author":"Ara\u00fajo","year":"2021","journal-title":"Nutrition"},{"key":"10.3168\/jds.2025-27163_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1371064","article-title":"A synbiotic mixture of Bifidobacterium breve M16-V, oligosaccharides and pectin, enhances short chain fatty acid production and improves lung health in a preclinical model for pulmonary neutrophilia","volume":"11","author":"Bezemer","year":"2024","journal-title":"Front. Nutr."},{"key":"10.3168\/jds.2025-27163_bib4","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1053\/j.gastro.2019.12.034","article-title":"Mechanisms, evaluation, and management of chronic constipation","volume":"158","author":"Bharucha","year":"2020","journal-title":"Gastroenterology"},{"key":"10.3168\/jds.2025-27163_bib5","doi-asserted-by":"crossref","first-page":"40814","DOI":"10.1074\/jbc.M111.286039","article-title":"\u03b1-Galactosidase\/sucrose kinase (AgaSK), a novel bifunctional enzyme from the human microbiome coupling galactosidase and kinase activities","volume":"286","author":"Bruel","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2025-27163_bib6","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.chom.2023.08.004","article-title":"Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites","volume":"31","author":"Button","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.3168\/jds.2025-27163_bib7","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/s41598-024-77864-y","article-title":"Key features and guidelines for the application of microbial alpha diversity metrics","volume":"15","author":"Cassol","year":"2025","journal-title":"Sci. Rep."},{"key":"10.3168\/jds.2025-27163_bib8","doi-asserted-by":"crossref","DOI":"10.1111\/1541-4337.13431","article-title":"Gut microbiota: A key role for human milk oligosaccharides in regulating host health early in life","volume":"23","author":"Chen","year":"2024","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.3168\/jds.2025-27163_bib9","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuad014","article-title":"Ruminococcus gnavus: Friend or foe for human health","volume":"47","author":"Crost","year":"2023","journal-title":"FEMS Microbiol. Rev."},{"key":"10.3168\/jds.2025-27163_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.02558","article-title":"Mechanistic insights into the cross-feeding of Ruminococcus gnavus and Ruminococcus bromii on host and dietary carbohydrates","volume":"9","author":"Crost","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.3168\/jds.2025-27163_bib11","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1080\/19490976.2016.1186334","article-title":"The mucin-degradation strategy of Ruminococcus gnavus: The importance of intramolecular trans-sialidases","volume":"7","author":"Crost","year":"2016","journal-title":"Gut Microbes"},{"key":"10.3168\/jds.2025-27163_bib12","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1007\/s00394-024-03410-1","article-title":"Network meta-analysis of probiotics, prebiotics, and synbiotics for the treatment of chronic constipation in adults","volume":"63","author":"Deng","year":"2024","journal-title":"Eur. J. Nutr."},{"key":"10.3168\/jds.2025-27163_bib13","author":"European Union"},{"key":"10.3168\/jds.2025-27163_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2024.105675","article-title":"Fecal-adherent mucus is a non-invasive source of primary human MUC2 for structural and functional characterization in health and disease","volume":"300","author":"Fancy","year":"2024","journal-title":"J. Biol. Chem."},{"key":"10.3168\/jds.2025-27163_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.02054","article-title":"Mucins in intestinal mucosal defense and inflammation: Learning from clinical and experimental studies","volume":"11","author":"Grondin","year":"2020","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-27163_bib16","article-title":"Latilactobacillus sakei Furu2019 and stachyose as probiotics, prebiotics, and synbiotics alleviate constipation in mice","volume":"9","author":"Guo","year":"2022","journal-title":"Front. Nutr."},{"key":"10.3168\/jds.2025-27163_bib17","article-title":"Positive association between constipation and mild cognitive impairment in elders: A cross-sectional study","volume":"103","author":"Huang","year":"2024","journal-title":"Medicine (Baltimore)"},{"key":"10.3168\/jds.2025-27163_bib18","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1080\/07388551.2024.2336531","article-title":"How do probiotics alleviate constipation? A narrative review of mechanisms","volume":"45","author":"Huang","year":"2025","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.3168\/jds.2025-27163_bib19","article-title":"The preparation of synbiotic AHY relieving loperamide-induced constipation and its modulation mechanism in vivo","volume":"59","author":"Jiang","year":"2024","journal-title":"Food Biosci."},{"key":"10.3168\/jds.2025-27163_bib20","doi-asserted-by":"crossref","DOI":"10.1111\/1541-4337.13271","article-title":"Gastrointestinal barrier function, immunity, and neurocognition: The role of human milk oligosaccharide (hMO) supplementation in infant formula","volume":"23","author":"Kassai","year":"2024","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.3168\/jds.2025-27163_bib21","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/s41392-021-00549-9","article-title":"Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome","volume":"6","author":"Kong","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.3168\/jds.2025-27163_bib22","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1007\/s12602-024-10346-9","article-title":"Exploring the potential probiotic properties of Bifidobacterium breve DSM 32583\u2014A novel strain isolated from human milk","volume":"17","author":"Kujawska","year":"2025","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"10.3168\/jds.2025-27163_bib23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s10620-006-9298-7","article-title":"Etiologic factors of chronic constipation: Review of the scientific evidence","volume":"52","author":"Leung","year":"2007","journal-title":"Dig. Dis. Sci."},{"key":"10.3168\/jds.2025-27163_bib24","doi-asserted-by":"crossref","first-page":"5702","DOI":"10.1039\/D2FO03574J","article-title":"Gut indigenous Ruminococcus gnavus alleviates constipation and stress-related behaviors in mice with loperamide-induced constipation","volume":"14","author":"Li","year":"2023","journal-title":"Food Funct."},{"key":"10.3168\/jds.2025-27163_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27072235","article-title":"The anti-constipation effects of Raffino-oligosaccharide on gut function in mice using neurotransmitter analyses, 16S rRNA sequencing and targeted screening","volume":"27","author":"Liang","year":"2022","journal-title":"Molecules"},{"key":"10.3168\/jds.2025-27163_bib26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ygcen.2018.11.016","article-title":"Localization of estrogen receptor ER\u03b1, ER\u03b2 and GPR30 on myenteric neurons of the gastrointestinal tract and their role in motility","volume":"272","author":"Liu","year":"2019","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.3168\/jds.2025-27163_bib27","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s13238-020-00724-8","article-title":"A practical guide to amplicon and metagenomic analysis of microbiome data","volume":"12","author":"Liu","year":"2021","journal-title":"Protein Cell"},{"key":"10.3168\/jds.2025-27163_bib28","first-page":"641","article-title":"Research progress in the relationship between gut microbia and its metabolites and gestational diabetes mellitus","volume":"43","author":"Liu","year":"2023","journal-title":"J. Shanghai Jiaotong Univ."},{"key":"10.3168\/jds.2025-27163_bib29","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1039\/D0FO02227F","article-title":"Bifidobacterium animalis F1\u20137 in combination with konjac glucomannan improves constipation in mice via humoral transport","volume":"12","author":"Lu","year":"2021","journal-title":"Food Funct."},{"key":"10.3168\/jds.2025-27163_bib30","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.chom.2023.05.026","article-title":"Intestinal mucus and their glycans: A habitat for thriving microbiota","volume":"31","author":"Luis","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.3168\/jds.2025-27163_bib31","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jpainsymman.2008.04.016","article-title":"A review of the literature on gender and age differences in the prevalence and characteristics of constipation in North America","volume":"37","author":"McCrea","year":"2009","journal-title":"J. Pain Symptom Manage."},{"key":"10.3168\/jds.2025-27163_bib32","doi-asserted-by":"crossref","first-page":"839","DOI":"10.2174\/1389557043403288","article-title":"Cellular and physiological effects of short-chain fatty acids","volume":"4","author":"Miller","year":"2004","journal-title":"Mini Rev. Med. Chem."},{"key":"10.3168\/jds.2025-27163_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctim.2020.102495","article-title":"How adding the abdominal massage to polyethylene glycol can improve symptom and quality of life in patients with functional constipation in comparison with each one of the treatment modalities alone: A randomized clinical trial","volume":"52","author":"Mokhtare","year":"2020","journal-title":"Complement. Ther. Med."},{"key":"10.3168\/jds.2025-27163_bib34","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4196\/kjpp.2013.17.5.423","article-title":"Estrogen rather than progesterone cause constipation in both female and male mice","volume":"17","author":"Oh","year":"2013","journal-title":"Korean J. Physiol. Pharmacol."},{"key":"10.3168\/jds.2025-27163_bib35","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1136\/gutjnl-2020-322260","article-title":"Mucus barrier, mucins and gut microbiota: The expected slimy partners?","volume":"69","author":"Paone","year":"2020","journal-title":"Gut"},{"key":"10.3168\/jds.2025-27163_bib36","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2022.2152307","article-title":"Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion","volume":"14","author":"Paone","year":"2022","journal-title":"Gut Microbes"},{"key":"10.3168\/jds.2025-27163_bib37","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1039\/D3FO02739B","article-title":"Determining the emotional regulation function of Bifidobacterium breve: The role of gut metabolite regulation over colonization capability","volume":"15","author":"Qian","year":"2024","journal-title":"Food Funct."},{"key":"10.3168\/jds.2025-27163_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/nu15081830","article-title":"Age-related mucus barrier dysfunction in mice is related to the changes in Muc2 mucin in the colon","volume":"15","author":"Sang","year":"2023","journal-title":"Nutrients"},{"key":"10.3168\/jds.2025-27163_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.idairyj.2025.106419","article-title":"Lacto-N-neotetraose alleviates obesity in mice by modulating the gut microbiota and short-chain fatty acid metabolism","volume":"172","author":"Shan","year":"2026","journal-title":"Int. Dairy J."},{"key":"10.3168\/jds.2025-27163_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.70024","article-title":"Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress-mediated Notch signaling","volume":"4","author":"Shi","year":"2025","journal-title":"iMeta"},{"key":"10.3168\/jds.2025-27163_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.134210","article-title":"Effect and mechanism of functional compound fruit drink on gut microbiota in constipation mice","volume":"401","author":"Shi","year":"2023","journal-title":"Food Chem."},{"key":"10.3168\/jds.2025-27163_bib42","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3177\/jnsv.51.287","article-title":"Histochemical structure of the mucus gel layer coating the fecal surface of rodents, rabbits and humans","volume":"51","author":"Shimotoyodome","year":"2005","journal-title":"J. Nutr. Sci. Vitaminol. (Tokyo)"},{"key":"10.3168\/jds.2025-27163_bib43","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/foods13010015","article-title":"Prospective randomized, double-blind, placebo-controlled study of a standardized oral pomegranate extract on the gut microbiome and short-chain fatty acids","volume":"13","author":"Sivamani","year":"2023","journal-title":"Foods"},{"key":"10.3168\/jds.2025-27163_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/nu12071999","volume":"12","author":"Skrzyd\u0142o-Radoma\u0144ska","year":"2020","journal-title":"Nutrients"},{"key":"10.3168\/jds.2025-27163_bib45","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/s12276-023-00960-y","article-title":"Intestinal mucus components and secretion mechanisms: What we do and do not know","volume":"55","author":"Song","year":"2023","journal-title":"Exp. Mol. Med."},{"key":"10.3168\/jds.2025-27163_bib46","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.atherosclerosis.2018.12.021","article-title":"Constipation and risk of death and cardiovascular events","volume":"281","author":"Sumida","year":"2019","journal-title":"Atherosclerosis"},{"key":"10.3168\/jds.2025-27163_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.953196","article-title":"Diet, microbiota, and the mucus layer: The guardians of our health","volume":"13","author":"Suriano","year":"2022","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-27163_bib48","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/01.mpg.0000221913.88511.72","article-title":"Probiotics in gastrointestinal diseases in children: Hard and not-so-hard evidence of efficacy","volume":"42","author":"Szajewska","year":"2006","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.3168\/jds.2025-27163_bib49","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1210\/endo.132.1.8419141","article-title":"The presence of functional estrogen receptors in intestinal epithelial cells","volume":"132","author":"Thomas","year":"1993","journal-title":"Endocrinology"},{"key":"10.3168\/jds.2025-27163_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1274559","article-title":"Therapeutic effects of curcumin on constipation-predominant irritable bowel syndrome is associated with modulating gut microbiota and neurotransmitters","volume":"14","author":"Tu","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.3168\/jds.2025-27163_bib51","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/MPG.0000000000001590","article-title":"Digestion of human milk oligosaccharides by Bifidobacterium breve in the premature infant","volume":"65","author":"Underwood","year":"2017","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.3168\/jds.2025-27163_bib52","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/apt.17782","article-title":"Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in adults","volume":"59","author":"Van Der Schoot","year":"2024","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.3168\/jds.2025-27163_bib53","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3390\/medicina60010108","article-title":"Idiopathic slow transit constipation: Pathophysiology, diagnosis, and management","volume":"60","author":"Vlismas","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.3168\/jds.2025-27163_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2020.103953","article-title":"Acetic acid and butyric acid released in large intestine play different roles in the alleviation of constipation","volume":"69","author":"Wang","year":"2020","journal-title":"J. Funct. Foods"},{"key":"10.3168\/jds.2025-27163_bib55","doi-asserted-by":"crossref","first-page":"5037","DOI":"10.1039\/D1FO04151G","article-title":"Bifidobacterium longum relieves constipation by regulating the intestinal barrier of mice","volume":"13","author":"Wang","year":"2022","journal-title":"Food Funct."},{"key":"10.3168\/jds.2025-27163_bib56","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001498","article-title":"The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract","volume":"19","author":"Wu","year":"2021","journal-title":"PLoS Biol."},{"key":"10.3168\/jds.2025-27163_bib57","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/postmj\/qgae112","article-title":"Chronic constipation and gut microbiota: Current research insights and therapeutic implications","volume":"100","author":"Xu","year":"2024","journal-title":"Postgrad. Med. J."},{"key":"10.3168\/jds.2025-27163_bib58","doi-asserted-by":"crossref","first-page":"10384","DOI":"10.1080\/10408398.2023.2224431","article-title":"Recent progress in fucosylated derivatives of lacto-N-tetraose and lacto-N-neotetraose","volume":"64","author":"Yang","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.3168\/jds.2025-27163_bib59","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1163\/18762891-bja00039","article-title":"Effects of complex probiotics on intestinal function and its regulatory mechanism in patients with constipation","volume":"16","author":"Zhang","year":"2024","journal-title":"Benef. Microbes"},{"key":"10.3168\/jds.2025-27163_bib60","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201801187","article-title":"Abundance of probiotics and butyrate-production microbiome manages constipation via short-chain fatty acids production and hormones secretion","volume":"63","author":"Zhuang","year":"2019","journal-title":"Mol. Nutr. Food Res."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226000457?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226000457?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T08:49:53Z","timestamp":1780649393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030226000457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S0022030226000457"],"URL":"https:\/\/doi.org\/10.3168\/jds.2025-27163","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bifidobacterium breve and lacto-N-neotetraose mediate gut microbiota-derived acetate to regulate defecation performance and intestinal barrier function in constipated mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2025-27163","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors.","name":"copyright","label":"Copyright"}]}}