{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:00:32Z","timestamp":1790805632923,"version":"4.1.0"},"reference-count":65,"publisher":"American Dairy Science Association","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002365","name":"China Agricultural University","doi-asserted-by":"publisher","award":["2024BBF02013"],"award-info":[{"award-number":["2024BBF02013"]}],"id":[{"id":"10.13039\/501100002365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002365","name":"China Agricultural University","doi-asserted-by":"publisher","award":["CARS-36"],"award-info":[{"award-number":["CARS-36"]}],"id":[{"id":"10.13039\/501100002365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002365","name":"China Agricultural University","doi-asserted-by":"publisher","award":["32125038"],"award-info":[{"award-number":["32125038"]}],"id":[{"id":"10.13039\/501100002365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016692","name":"Key Research and Development Program of Ningxia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016692","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.3168\/jds.2025-27861","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T23:23:18Z","timestamp":1780960998000},"page":"9910-9930","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Succinate\/SUCNR1-mediated regulation of macrophage polarization reduces trophoblast apoptosis: A potential cause of retained placenta in peripartal dairy cows"],"prefix":"10.3168","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3775-2510","authenticated-orcid":false,"given":"Huijing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bichen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renxu","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2995-5494","authenticated-orcid":false,"given":"Jingyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingnian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihao","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenda","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1586-4365","authenticated-orcid":false,"given":"Juan J.","family":"Loor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0377-1439","authenticated-orcid":false,"given":"Chuang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2025-27861_bib1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/rda.14115","article-title":"Latest update on predictive indicators, risk factors and \u2018Omic\u2019 technologies research of retained placenta in dairy cattle\u2014A review","volume":"57","author":"Amin","year":"2022","journal-title":"Reprod. Domest. Anim."},{"key":"10.3168\/jds.2025-27861_bib2","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aat6114","article-title":"Immune responses at the maternal-fetal interface","volume":"4","author":"Ander","year":"2019","journal-title":"Sci. Immunol."},{"key":"10.3168\/jds.2025-27861_bib3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1530\/rep.0.1260469","article-title":"Proliferation and apoptosis in bovine placentomes during pregnancy and around induced and spontaneous parturition as well as in cows retaining the fetal membranes","volume":"126","author":"Boos","year":"2003","journal-title":"Reproduction"},{"key":"10.3168\/jds.2025-27861_bib4","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3389\/fimmu.2014.00606","article-title":"M1\/M2 macrophage polarity in normal and complicated pregnancy","volume":"5","author":"Brown","year":"2014","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-27861_bib5","article-title":"JPT2 affects trophoblast functions and macrophage polarization and metabolism, and acts as a potential therapeutic target for recurrent spontaneous abortion","volume":"11","author":"Chen","year":"2024","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.3168\/jds.2025-27861_bib6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.anireprosci.2004.05.016","article-title":"Major histocompatibility antigen expression on the bovine placenta: Its relationship to abnormal pregnancies and retained placenta","volume":"82\u201383","author":"Davies","year":"2004","journal-title":"Anim. Reprod. Sci."},{"key":"10.3168\/jds.2025-27861_bib7","first-page":"2376","article-title":"FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage","volume":"43","author":"Ding","year":"2019","journal-title":"Int. J. Mol. Med."},{"key":"10.3168\/jds.2025-27861_bib8","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1146\/annurev-immunol-032712-100003","article-title":"Immunology of the maternal-fetal interface","volume":"31","author":"Erlebacher","year":"2013","journal-title":"Annu. Rev. Immunol."},{"key":"10.3168\/jds.2025-27861_bib9","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/sj.cdd.4401160","article-title":"Many cuts to ruin: A comprehensive update of caspase substrates","volume":"10","author":"Fischer","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.3168\/jds.2025-27861_bib10","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.cell.2017.07.029","article-title":"The PI3K pathway in human disease","volume":"170","author":"Fruman","year":"2017","journal-title":"Cell"},{"key":"10.3168\/jds.2025-27861_bib11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.pharmthera.2016.01.008","article-title":"Insight into SUCNR1 (GPR91) structure and function","volume":"159","author":"Gilissen","year":"2016","journal-title":"Pharmacol. Ther."},{"key":"10.3168\/jds.2025-27861_bib12","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.2460\/javma.252.12.1485","article-title":"Cost of retained fetal membranes for dairy herds in the United States","volume":"252","author":"Gohary","year":"2018","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.3168\/jds.2025-27861_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4142\/jvs.2005.6.1.53","article-title":"Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows","volume":"6","author":"Han","year":"2005","journal-title":"J. Vet. Sci."},{"key":"10.3168\/jds.2025-27861_bib14","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1093\/humrep\/deab225","article-title":"Decreased nitric oxide content mediated by asymmetrical dimethylarginine and protein l-arginine methyltransferase 3 in macrophages induces trophoblast apoptosis: A potential cause of recurrent miscarriage","volume":"36","author":"Hao","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.3168\/jds.2025-27861_bib15","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3390\/metabo10090372","article-title":"Succinate is an inflammation-induced immunoregulatory metabolite in macrophages","volume":"10","author":"Harber","year":"2020","journal-title":"Metabolites"},{"key":"10.3168\/jds.2025-27861_bib16","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/nature02488","article-title":"Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors","volume":"429","author":"He","year":"2004","journal-title":"Nature"},{"key":"10.3168\/jds.2025-27861_bib17","doi-asserted-by":"crossref","first-page":"6555","DOI":"10.1038\/ncomms7555","article-title":"Xanthine oxidoreductase regulates macrophage IL1\u03b2 secretion upon NLRP3 inflammasome activation","volume":"6","author":"Ives","year":"2015","journal-title":"Nat. Commun."},{"key":"10.3168\/jds.2025-27861_bib18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00005-019-00552-7","article-title":"Role of macrophages in pregnancy and related complications","volume":"67","author":"Jena","year":"2019","journal-title":"Arch. Immunol. Ther. Exp. (Warsz.)"},{"key":"10.3168\/jds.2025-27861_bib19","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.mam.2012.12.008","article-title":"Placental trophoblast cell differentiation: Physiological regulation and pathological relevance to preeclampsia","volume":"34","author":"Ji","year":"2013","journal-title":"Mol. Aspects Med."},{"key":"10.3168\/jds.2025-27861_bib20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.placenta.2010.10.016","article-title":"Expressions of apoptosis-regulating factors in bovine retained placenta","volume":"32","author":"Kamemori","year":"2011","journal-title":"Placenta"},{"key":"10.3168\/jds.2025-27861_bib21","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/s41590-019-0372-7","article-title":"SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity","volume":"20","author":"Keiran","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.3168\/jds.2025-27861_bib22","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/cr.2015.68","article-title":"Metabolic reprogramming in macrophages and dendritic cells in innate immunity","volume":"25","author":"Kelly","year":"2015","journal-title":"Cell Res."},{"key":"10.3168\/jds.2025-27861_bib23","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.it.2020.11.004","article-title":"Succinate receptor 1: An emerging regulator of myeloid cell function in inflammation","volume":"42","author":"Krzak","year":"2021","journal-title":"Trends Immunol."},{"key":"10.3168\/jds.2025-27861_bib24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s12929-022-00878-z","article-title":"Cancer-derived extracellular succinate: A driver of cancer metastasis","volume":"29","author":"Kuo","year":"2022","journal-title":"J. Biomed. Sci."},{"key":"10.3168\/jds.2025-27861_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.244","article-title":"Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus","volume":"7","author":"Li","year":"2016","journal-title":"Cell Death Dis."},{"key":"10.3168\/jds.2025-27861_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114408","article-title":"Dietary succinate supplementation alleviates DSS-induced colitis via the IL-4R\u03b1\/Hif-1\u03b1 axis","volume":"152","author":"Liang","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.3168\/jds.2025-27861_bib27","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1111\/febs.17407","article-title":"Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism","volume":"292","author":"Liebing","year":"2025","journal-title":"FEBS J."},{"key":"10.3168\/jds.2025-27861_bib28","article-title":"Structural insights into ligand recognition and activation of the succinate receptor SUCNR1","volume":"43","author":"Liu","year":"2024","journal-title":"Cell Rep."},{"key":"10.3168\/jds.2025-27861_bib29","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s10555-006-9001-7","article-title":"Role of tumor-associated macrophages in tumor progression and invasion","volume":"25","author":"Mantovani","year":"2006","journal-title":"Cancer Metastasis Rev."},{"key":"10.3168\/jds.2025-27861_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2007.05.010","article-title":"Taking tissue samples from the placenta: An illustration of principles and strategies","volume":"29","author":"Mayhew","year":"2008","journal-title":"Placenta"},{"key":"10.3168\/jds.2025-27861_bib31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1439-0531.2004.00484.x","article-title":"Specific localization of macrophages in pregnant bovine caruncles","volume":"39","author":"Miyoshi","year":"2004","journal-title":"Reprod. Domest. Anim."},{"issue":"Suppl. 1","key":"10.3168\/jds.2025-27861_bib32","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.3168\/jds.2006-478","article-title":"Ruminal acidosis in beef cattle: The current microbiological and nutritional outlook","volume":"90","author":"Nagaraja","year":"2007","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27861_bib33","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/j.1600-0897.2009.00761.x","article-title":"Phenotypic characterization of macrophages in the endometrium of the pregnant cow","volume":"62","author":"Oliveira","year":"2009","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.3168\/jds.2025-27861_bib34","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adg8842","article-title":"A succinate\/SUCNR1-brush cell defense program in the tracheal epithelium","volume":"9","author":"Perniss","year":"2023","journal-title":"Sci. Adv."},{"key":"10.3168\/jds.2025-27861_bib35","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.stem.2018.01.020","article-title":"Macrophage-derived extracellular succinate licenses neural stem cells to suppress chronic neuroinflammation","volume":"22","author":"Peruzzotti-Jametti","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.3168\/jds.2025-27861_bib36","doi-asserted-by":"crossref","first-page":"6647","DOI":"10.3168\/jds.2019-17867","article-title":"Associations of reproductive indices with fertility outcomes, milk yield, and survival in Holstein cows","volume":"103","author":"Pinedo","year":"2020","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27861_bib37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1161\/CIRCRESAHA.116.308304","article-title":"CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia","volume":"119","author":"Przybyl","year":"2016","journal-title":"Circ. Res."},{"key":"10.3168\/jds.2025-27861_bib38","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1186\/s12951-024-02997-1","article-title":"Succinate exacerbates mastitis in mice via extracellular vesicles derived from the gut microbiota: A potential new mechanism for mastitis","volume":"22","author":"Qiu","year":"2024","journal-title":"J. Nanobiotechnology"},{"key":"10.3168\/jds.2025-27861_bib39","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.it.2023.10.004","article-title":"Macrophage phenotypes and functions: Resolving inflammation and restoring homeostasis","volume":"44","author":"Rodr\u00edguez-Morales","year":"2023","journal-title":"Trends Immunol."},{"key":"10.3168\/jds.2025-27861_bib40","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/ni.1657","article-title":"Triggering the succinate receptor GPR91 on dendritic cells enhances immunity","volume":"9","author":"Rubic","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.3168\/jds.2025-27861_bib41","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/nm.1873","article-title":"The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis","volume":"14","author":"Sapieha","year":"2008","journal-title":"Nat. Med."},{"key":"10.3168\/jds.2025-27861_bib42","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0165-2427(94)05348-V","article-title":"Immortalization and characterization of bovine peritoneal macrophages transfected with SV40 plasmid DNA","volume":"45","author":"Stabel","year":"1995","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3168\/jds.2025-27861_bib43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1262\/jrd.2021-077","article-title":"Exosomes derived from placental trophoblast cells regulate endometrial epithelial receptivity in dairy cows during pregnancy","volume":"68","author":"Su","year":"2022","journal-title":"J. Reprod. Dev."},{"key":"10.3168\/jds.2025-27861_bib44","doi-asserted-by":"crossref","first-page":"7423","DOI":"10.3168\/jds.2023-24357","article-title":"Fatty acids promote M1 polarization of monocyte-derived macrophages in healthy or ketotic dairy cows and a bovine macrophage cell line by impairing mTOR-mediated autophagy","volume":"107","author":"Sun","year":"2024","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27861_bib45","article-title":"Targeting SLITRK4 restrains proliferation and liver metastasis in colorectal cancer via regulating PI3K\/AKT\/NF\u03baB pathway and tumor-associated macrophage","volume":"12","author":"Sun","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.3168\/jds.2025-27861_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109246","article-title":"Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1\/GPR91-mediated Gq signaling","volume":"35","author":"Trauelsen","year":"2021","journal-title":"Cell Rep."},{"key":"10.3168\/jds.2025-27861_bib47","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.bbabio.2016.03.012","article-title":"Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis","volume":"1857","author":"Tretter","year":"2016","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"10.3168\/jds.2025-27861_bib48","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.cmet.2023.03.004","article-title":"SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression","volume":"35","author":"Villanueva-Carmona","year":"2023","journal-title":"Cell Metab."},{"key":"10.3168\/jds.2025-27861_bib49","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1016\/j.celrep.2018.10.103","article-title":"The mitochondrial apoptotic effectors BAX\/BAK activate caspase-3 and -7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1\u03b2 activation","volume":"25","author":"Vince","year":"2018","journal-title":"Cell Rep."},{"key":"10.3168\/jds.2025-27861_bib50","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1038\/s41467-021-23827-0","article-title":"Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk","volume":"12","author":"Wang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.3168\/jds.2025-27861_bib51","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1006\/jmbi.2001.4520","article-title":"An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors","volume":"307","author":"Wittenberger","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.3168\/jds.2025-27861_bib52","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1093\/biolre\/ioac107","article-title":"The ruminant placental trophoblast binucleate cell: An evolutionary breakthrough","volume":"107","author":"Wooding","year":"2022","journal-title":"Biol. Reprod."},{"key":"10.3168\/jds.2025-27861_bib53","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.molcel.2019.10.023","article-title":"Cancer-derived succinate promotes macrophage polarization and cancer metastasis via succinate receptor","volume":"77","author":"Wu","year":"2020","journal-title":"Mol. Cell"},{"key":"10.3168\/jds.2025-27861_bib54","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s40104-024-01089-2","article-title":"Curcumin attenuates ochratoxin A and hypoxia co-induced liver injury in grass carp (Ctenopharyngodon idella) by dual targeting endoplasmic reticulum stress and apoptosis via reducing ROS content","volume":"15","author":"Wu","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.3168\/jds.2025-27861_bib55","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.immuni.2014.01.006","article-title":"Transcriptome-based network analysis reveals a spectrum model of human macrophage activation","volume":"40","author":"Xue","year":"2014","journal-title":"Immunity"},{"key":"10.3168\/jds.2025-27861_bib56","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.theriogenology.2019.01.020","article-title":"The evaluation of superoxide dismutase activity, neutrophil function, and metabolic profile in cows with retained placenta","volume":"128","author":"Yazl\u0131k","year":"2019","journal-title":"Theriogenology"},{"key":"10.3168\/jds.2025-27861_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e11686","article-title":"The role of macrophages in reproductive-related diseases","volume":"8","author":"Zhang","year":"2022","journal-title":"Heliyon"},{"key":"10.3168\/jds.2025-27861_bib58","doi-asserted-by":"crossref","first-page":"7437","DOI":"10.3168\/jds.2024-26144","article-title":"Evidence for imbalanced polarization of caruncle macrophages in retained placenta of dairy cows","volume":"108","author":"Zhang","year":"2025","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2025-27861_bib59","article-title":"miR-196a-5p-rich extracellular vesicles from trophoblasts induce M1 polarization of macrophages in recurrent miscarriage","volume":"2022","author":"Zhang","year":"2022","journal-title":"J. Immunol. Res."},{"key":"10.3168\/jds.2025-27861_bib60","article-title":"Novel secreted protein of Mycoplasma bovis MbovP280 induces macrophage apoptosis through CRYAB","volume":"12","author":"Zhao","year":"2021","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-27861_bib61","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.994888","article-title":"Decidual macrophages in recurrent spontaneous abortion","volume":"13","author":"Zhao","year":"2022","journal-title":"Front. Immunol."},{"key":"10.3168\/jds.2025-27861_bib62","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s13045-020-00991-2","article-title":"Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer","volume":"13","author":"Zhao","year":"2020","journal-title":"J. Hematol. Oncol."},{"key":"10.3168\/jds.2025-27861_bib63","doi-asserted-by":"crossref","first-page":"17","DOI":"10.7150\/thno.36930","article-title":"Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K\/AKT\/GSK3\u03b2\/\u03b2-catenin pathway","volume":"10","author":"Zhao","year":"2020","journal-title":"Theranostics"},{"key":"10.3168\/jds.2025-27861_bib64","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.freeradbiomed.2024.06.029","article-title":"Excessive palmitic acid disturbs macrophage \u03b1-ketoglutarate\/succinate metabolism and causes adipose tissue insulin resistance associated with gestational diabetes mellitus","volume":"222","author":"Zhao","year":"2024","journal-title":"Free Radic. Biol. Med."},{"key":"10.3168\/jds.2025-27861_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.115310","article-title":"Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms","volume":"44","author":"Zhou","year":"2025","journal-title":"Cell Rep."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226029073?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226029073?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:26:31Z","timestamp":1790803591000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030226029073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":65,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S0022030226029073"],"URL":"https:\/\/doi.org\/10.3168\/jds.2025-27861","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Succinate\/SUCNR1-mediated regulation of macrophage polarization reduces trophoblast apoptosis: A potential cause of retained placenta in peripartal dairy cows","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2025-27861","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s).","name":"copyright","label":"Copyright"}]}}