{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T20:03:01Z","timestamp":1789848181823,"version":"4.0.1"},"reference-count":42,"publisher":"American Dairy Science Association","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008238","name":"Hebei Province Department of Science And Technology","doi-asserted-by":"publisher","award":["2026JNZ-F02"],"award-info":[{"award-number":["2026JNZ-F02"]}],"id":[{"id":"10.13039\/501100008238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015308","name":"Xinjiang Uygur Autonomous Region Department of Science and Technology","doi-asserted-by":"publisher","award":["2025B04004-002"],"award-info":[{"award-number":["2025B04004-002"]}],"id":[{"id":"10.13039\/501100015308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014205","name":"National Dairy Industry and Technology System","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014205","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005196","name":"Chinese Academy of Agricultural Sciences","doi-asserted-by":"publisher","award":["CARS-36"],"award-info":[{"award-number":["CARS-36"]}],"id":[{"id":"10.13039\/501100005196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofdairyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Dairy Science"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.3168\/jds.2026-28537","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:20:43Z","timestamp":1789665643000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Liposomal encapsulation and characterization of casein-derived peptides obtained by enzymatic hydrolysis coupled with microfiltration: In vivo evaluation of anti-fatigue activity"],"prefix":"10.3168","author":[{"given":"Yining","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengpeng","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruican","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunna","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1747","reference":[{"key":"10.3168\/jds.2026-28537_bib1","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3390\/antiox11051025","article-title":"Plant- and Animal-Based Antioxidants' Structure, Efficacy, Mechanisms, and Applications: A Review","volume":"11","author":"Abeyrathne","year":"2022","journal-title":"Antioxidants"},{"key":"10.3168\/jds.2026-28537_bib2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3168\/jds.2016-11846","article-title":"Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains","volume":"100","author":"Aguilar-Toala","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.3168\/jds.2026-28537_bib3","first-page":"229","article-title":"ANTIOXIDATIVE ACTIVITY OF CAMEL MILK CASEIN HYDROLYSATES","volume":"21","author":"Al-Saleh","year":"2014","journal-title":"J. Camel Pract. Res."},{"key":"10.3168\/jds.2026-28537_bib4","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3390\/molecules26020430","article-title":"A Global Review on Short Peptides: Frontiers and Perspectives","volume":"26","author":"Apostolopoulos","year":"2021","journal-title":"Molecules"},{"key":"10.3168\/jds.2026-28537_bib5","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.1111\/1750-3841.15918","article-title":"Identification and characterization of antioxidant peptides obtained from the bioaccessible fraction of \u03b1-lactalbumin hydrolysate","volume":"86","author":"Baez","year":"2021","journal-title":"J. Food Sci."},{"key":"10.3168\/jds.2026-28537_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105577","article-title":"Direct Keap1-kelch inhibitors as potential drug candidates for oxidative stress-orchestrated diseases: A review on In ilico perspective","volume":"167","author":"Boyenle","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.3168\/jds.2026-28537_bib7","doi-asserted-by":"crossref","first-page":"15522","DOI":"10.1021\/acs.jafc.3c02281","article-title":"Effect of Yeast-Derived Peptides on Skeletal Muscle Function and Exercise-Induced Fatigue in C2C12 Myotube Cells and ICR Mice","volume":"71","author":"Cai","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.3168\/jds.2026-28537_bib8","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.nut.2013.05.003","article-title":"Distinct effects of leucine or a mixture of the branched-chain amino acids (leucine, isoleucine, and valine) supplementation on resistance to fatigue, and muscle and liver-glycogen degradation, in trained rats","volume":"29","author":"Campos-Ferraz","year":"2013","journal-title":"Nutrition"},{"key":"10.3168\/jds.2026-28537_bib9","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1007\/s00424-020-02417-x","article-title":"Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease","volume":"472","author":"Chadt","year":"2020","journal-title":"Pflugers Arch."},{"key":"10.3168\/jds.2026-28537_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2019.e01538","article-title":"Antioxidant properties and potential mechanisms of hydrolyzed proteins and peptides from cereals","volume":"5","author":"Esfandi","year":"2019","journal-title":"Heliyon"},{"key":"10.3168\/jds.2026-28537_bib11","doi-asserted-by":"crossref","first-page":"7241","DOI":"10.7150\/thno.97593","article-title":"ZNF131-BACH1 transcriptionally accelerates RAD51-dependent homologous recombination repair and therapy-resistance of non-small-lung cancer cells by preventing their degradation from CUL3","volume":"14","author":"Fan","year":"2024","journal-title":"Theranostics"},{"key":"10.3168\/jds.2026-28537_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.103636","article-title":"Application of in silico approaches for the generation of milk protein-derived bioactive peptides","volume":"64","author":"FitzGerald","year":"2020","journal-title":"J. Funct. Foods"},{"key":"10.3168\/jds.2026-28537_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.fochx.2025.102652","article-title":"Liposome encapsulation for casein-derived peptides: Release behavior, in vitro digestibility, nutrient absorption, and gut microbiota","volume":"29","author":"Gong","year":"2025","journal-title":"Food Chem. X"},{"key":"10.3168\/jds.2026-28537_bib14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.aninu.2018.05.004","article-title":"Potential antioxidant bioactive peptides from camel milk proteins","volume":"4","author":"Ibrahim","year":"2018","journal-title":"Anim. Nutr."},{"key":"10.3168\/jds.2026-28537_bib15","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s13197-018-3549-4","article-title":"Bioactive food derived peptides: a review on correlation between structure of bioactive peptides and their functional properties","volume":"56","author":"Karami","year":"2019","journal-title":"J. Food Sci. Technol."},{"key":"10.3168\/jds.2026-28537_bib16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s43014-024-00280-2","article-title":"Milk-derived bioactive peptides","volume":"7","author":"Kashung","year":"2025","journal-title":"Food Production Processing and Nutrition"},{"key":"10.3168\/jds.2026-28537_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/2784146","article-title":"Effect of Low-Frequency Ultrasonic-Assisted Enzymolysis on the Physicochemical and Antioxidant Properties of Corn Protein Hydrolysates","volume":"2784146","author":"Liang","year":"2017","journal-title":"J. Food Qual."},{"key":"10.3168\/jds.2026-28537_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2021.112194","article-title":"Production and transepithelial transportation of casein-derived peptides and identification a novel antioxidant peptide LHSMK","volume":"151","author":"Liu","year":"2021","journal-title":"Lebensm. Wiss. Technol."},{"key":"10.3168\/jds.2026-28537_bib19","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.3390\/molecules27041372","article-title":"A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives","volume":"27","author":"Liu","year":"2022","journal-title":"Molecules"},{"key":"10.3168\/jds.2026-28537_bib20","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1021\/acs.jafc.0c05982","article-title":"Preparation of Casein Biopeptide-Loaded Niosomes by High Shear Homogenization and Their Characterization","volume":"69","author":"Mor","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.3168\/jds.2026-28537_bib21","doi-asserted-by":"crossref","first-page":"11510","DOI":"10.1080\/10408398.2023.2240396","article-title":"Bioactive milk peptides: an updated comprehensive overview and database","volume":"64","author":"Nielsen","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.3168\/jds.2026-28537_bib22","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.tifs.2016.01.022","article-title":"Strategies for the discovery, identification and validation of milk protein-derived bioactive peptides","volume":"50","author":"Nongonierma","year":"2016","journal-title":"Trends Food Sci. Technol."},{"key":"10.3168\/jds.2026-28537_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.fochx.2022.100370","article-title":"Ultrasonication for production of nanoliposomes with encapsulated soy protein concentrate hydrolysate: Process optimization, vesicle characteristics and in vitro digestion","volume":"15","author":"Pavlovic","year":"2022","journal-title":"Food Chem. X"},{"key":"10.3168\/jds.2026-28537_bib24","doi-asserted-by":"crossref","DOI":"10.1590\/fst.93021","article-title":"Anti-fatigue effect of small molecule oligopeptides from tilapia (<i>Oreochromis Mossambicus<\/i>) in mice","volume":"42","author":"Peng","year":"2022","journal-title":"Food Sci. Technol. (Campinas)"},{"key":"10.3168\/jds.2026-28537_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2022.112095","article-title":"Elucidating the mechanism underlying volatile and non-volatile compound development related to microbial amino acid metabolism during golden pomfret (Trachinotus ovatus) fermentation","volume":"162","author":"Qiu","year":"2022","journal-title":"Food Res. Int."},{"key":"10.3168\/jds.2026-28537_bib26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.foodres.2004.10.002","article-title":"Purification of a radical scavenging peptide from fermented mussel sauce and its antioxidant properties","volume":"38","author":"Rajapakse","year":"2005","journal-title":"Food Res. Int."},{"key":"10.3168\/jds.2026-28537_bib27","doi-asserted-by":"crossref","first-page":"4562","DOI":"10.1007\/s13197-020-04495-2","article-title":"Impact of sequential enzymatic hydrolysis on antioxidant activity and peptide profile of casein hydrolysate","volume":"57","author":"Rao","year":"2020","journal-title":"J. Food Sci. Technol."},{"key":"10.3168\/jds.2026-28537_bib28","doi-asserted-by":"crossref","first-page":"10149","DOI":"10.1039\/D0FO01803A","article-title":"Structural characterization, erythrocyte protection, and antifatigue effect of antioxidant collagen peptides from tilapia (Oreochromis nilotica L.) skin","volume":"11","author":"Ren","year":"2020","journal-title":"Food Funct."},{"key":"10.3168\/jds.2026-28537_bib29","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1152\/physrev.00038.2012","article-title":"EXERCISE, GLUT4, AND SKELETAL MUSCLE GLUCOSE UPTAKE","volume":"93","author":"Richter","year":"2013","journal-title":"Physiol. Rev."},{"key":"10.3168\/jds.2026-28537_bib30","doi-asserted-by":"crossref","first-page":"5148","DOI":"10.1080\/07391102.2019.1696704","article-title":"Homology modeling, virtual screening and dynamics study of proteins involved in Pebrine-Serine protease inhibitor 106 and spore wall protein 26","volume":"38","author":"Shravan","year":"2020","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.3168\/jds.2026-28537_bib31","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1002\/jsfa.6671","article-title":"Antioxidant and anti-fatigue activities of egg white peptides prepared by pepsin digestion","volume":"94","author":"Sun","year":"2014","journal-title":"J. Sci. Food Agric."},{"key":"10.3168\/jds.2026-28537_bib32","article-title":"Effects of dietary histidine level on growth, antioxidant capacity and TOR signaling pathway in juvenile swimming crabs, Portunus trituberculatus","volume":"33","author":"Tian","year":"2023","journal-title":"Aquacult. Rep."},{"key":"10.3168\/jds.2026-28537_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.103696","article-title":"Milk-derived bioactive peptides exhibit antioxidant activity through the Keapl-Nrf2 signaling pathway","volume":"64","author":"Tonolo","year":"2020","journal-title":"J. Funct. Foods"},{"key":"10.3168\/jds.2026-28537_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2025.109863","article-title":"Quinoa protein and its hydrolysate improve the fatigue resistance of mice: a potential mechanism to relieve oxidative stress and inflammation and improve energy metabolism","volume":"139","author":"Tuo","year":"2025","journal-title":"J. Nutr. Biochem."},{"key":"10.3168\/jds.2026-28537_bib35","article-title":"The composition, microstructure, interaction with polysaccharides of casein micelles and their potential application as drug delivery-a review","volume":"65","author":"Wang","year":"2025","journal-title":"Food Biosci."},{"key":"10.3168\/jds.2026-28537_bib36","doi-asserted-by":"crossref","first-page":"9072","DOI":"10.3390\/ijms25169072","article-title":"Functional Peptides from Yak Milk Casein: Biological Activities and Structural Characteristics","volume":"25","author":"Wang","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.3168\/jds.2026-28537_bib37","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.tox.2018.08.010","article-title":"Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats","volume":"409","author":"Yang","year":"2018","journal-title":"Toxicology"},{"key":"10.3168\/jds.2026-28537_bib38","series-title":"Research on the Preparation of Casein Oligopeptides and Functional Product Development by Enzyme Membranes","author":"Yao","year":"2023"},{"key":"10.3168\/jds.2026-28537_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105807","article-title":"Skeletal muscle atrophy: From mechanisms to treatments","volume":"172","author":"Yin","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.3168\/jds.2026-28537_bib40","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.foodchem.2010.06.007","article-title":"In vitro antioxidant activity and in vivo anti-fatigue effect of loach (Misgurnus anguillicaudatus) peptides prepared by papain digestion","volume":"124","author":"You","year":"2011","journal-title":"Food Chem."},{"key":"10.3168\/jds.2026-28537_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115425","article-title":"Identification and action mechanism of novel antioxidative peptides from copra meal protein","volume":"188","author":"Zhang","year":"2023","journal-title":"Lebensm. Wiss. Technol."},{"key":"10.3168\/jds.2026-28537_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.140012","article-title":"Milk serum peptidomics revealed the age gelation of direct UHT milk","volume":"456","author":"Zhang","year":"2024","journal-title":"Food Chem."}],"container-title":["Journal of Dairy Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226032662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022030226032662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T19:21:43Z","timestamp":1789845703000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022030226032662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":42,"alternative-id":["S0022030226032662"],"URL":"https:\/\/doi.org\/10.3168\/jds.2026-28537","relation":{},"ISSN":["0022-0302"],"issn-type":[{"value":"0022-0302","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liposomal encapsulation and characterization of casein-derived peptides obtained by enzymatic hydrolysis coupled with microfiltration: In vivo evaluation of anti-fatigue activity","name":"articletitle","label":"Article Title"},{"value":"Journal of Dairy Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3168\/jds.2026-28537","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s).","name":"copyright","label":"Copyright"}]}}