{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:33:22Z","timestamp":1783776802515,"version":"3.55.0"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:p>The case of a 3-year-old patient with tuberous sclerosis and a 13-mm Chiari malformation Type I that spontaneously disappeared over the course of 4 years is presented. Using morphometric measurements of the posterior fossa and cerebellum in this patient, the authors show that the volume of the posterior fossa at the time of initial evaluation was consistent with that reported as normal in the literature (180.24 cm<jats:sup>3<\/jats:sup>; normal volume 132\u2013198 cm<jats:sup>3<\/jats:sup>). Moreover, the patient showed a normal rate of growth of his posterior fossa over the period of observation (201.05 cm<jats:sup>3<\/jats:sup>; normal range 153\u2013230 cm<jats:sup>3<\/jats:sup>). Cerebellar volumes were found to increase only minimally during this time period, which is compatible with observations in healthy controls. The posterior fossa volume, on the other hand, was shown to increase significantly more than that of the cerebellum (p = 0.0185). This differential growth may permit the tonsils to ascend back up into the posterior fossa. Therefore, pediatric patients with normal posterior fossa volumes and normal development may have a spontaneous resolution of their asymptomatic Chiari malformation Type I.<\/jats:p>","DOI":"10.3171\/2008.10.peds08200","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T12:26:24Z","timestamp":1253622384000},"page":"110-114","source":"Crossref","is-referenced-by-count":20,"title":["Spontaneous resolution of a 13-mm Chiari malformation Type I in relation to differential growth of the posterior fossa volume"],"prefix":"10.3171","volume":"3","author":[{"given":"Ben","family":"Waldau","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leahthan F.","family":"Domeshek","sequence":"additional","affiliation":[{"name":"Interdisciplinary Craniofacial Imaging Lab;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawn A.","family":"Leigh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neurology; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian C.","family":"Lum","sequence":"additional","affiliation":[{"name":"Department of Statistical Science, Duke University, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert E.","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Marcus","sequence":"additional","affiliation":[{"name":"Interdisciplinary Craniofacial Imaging Lab;"},{"name":"Department of Surgery, Division of Plastic and Reconstructive Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivasan","family":"Mukundan","sequence":"additional","affiliation":[{"name":"Interdisciplinary Craniofacial Imaging Lab;"},{"name":"Department of Radiology;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald A.","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0030110","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000028760","article-title":"Spontaneous resolution of a cervicothoracic syrinx in a child. 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