{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:06:57Z","timestamp":1787170017137,"version":"build-2736575974"},"reference-count":8,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2009,3]]},"abstract":"\n Object<\/jats:title>\n Angiocentric glioma was recently recognized as a distinct clinicopathological entity in the 2007 World Health Organization Classification of Tumours of the Central Nervous System. The authors present the first 3 pediatric cases of angiocentric glioma encountered at their institution and review the literature of reported cases to elucidate the characteristics and outcomes of pediatric patients with this novel tumor.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The children in the 3 cases of angiocentric glioma were 10, 10, and 13 years old. Two presented with intractable seizures and 1 with worsening headache and several months of decreasing visual acuity. Twenty-five cases, including the 3 first described in the present paper, were culled from the literature.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n In all 3 cases, MR imaging demonstrated a superficial, nonenhancing, T2-hyperintense lesion in the left temporal lobe. Histologically, the tumors were composed of monomorphous cells with a strikingly perivascular orientation that were variably reactive for glial fibrillary acidic protein and epithelial membrane antigen. Surgical treatment resulted in gross-total resection in all 3 cases. By 24, 9, and 6 months after surgery, all 3 patients remained seizure free without focal neurological deficits.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Among 25 cases of angiocentric glioma, seizure was the most common symptom at presentation. Magnetic resonance imaging demonstrated supratentorial, nonenhancing, T1-hypointense, T2-hyperintense lesions. Gross-total resection of this lesion yields excellent results.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2008.11.peds0858","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T08:27:41Z","timestamp":1253608061000},"page":"197-202","source":"Crossref","is-referenced-by-count":59,"title":["Angiocentric glioma: a case series"],"prefix":"10.3171","volume":"3","author":[{"given":"Sophia F.","family":"Shakur","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"McGirt","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.","family":"Burger","sequence":"additional","affiliation":[{"name":"Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Ahn","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin S.","family":"Carson","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George I.","family":"Jallo","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0030197","series-title":"Brain Pathol","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1111\/j.1750-3639.2007.00082.x","article-title":"Newly codified glial neoplasms of the 2007 WHO classification of tumors of the central nervous system: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma","volume":"17","author":"Brat","year":"2007"},{"key":"b2-0030197","series-title":"Acta Neurol Scand","first-page":"8","article-title":"Surgical treatment of epilepsy\u2014clinical, radiological and histopathological findings in 139 children and adults","volume":"99","author":"Eriksson","year":"1999"},{"key":"b3-0030197","series-title":"Brain Pathol","first-page":"281","article-title":"Angiocentric neuroepithelial tumor (ANET): a new epilepsy-related clinicopathological entity with distinctive MRI","volume":"15","author":"Lellouch-Tubiana","year":"2005"},{"key":"b4-0030197","series-title":"Acta Neuropathol","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00401-007-0243-4","article-title":"The 2007 WHO classification of tumours of the central nervous system","volume":"114","author":"Louis","year":"2007"},{"key":"b5-0030197","series-title":"Neuropathology","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1111\/j.1440-1789.2007.00831.x","article-title":"Cortical ependymoma or monomorphous angiocentric glioma","volume":"28","author":"Lum","year":"2008"},{"key":"b6-0030197","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1097\/PAS.0b013e31804a7ebb","article-title":"Angiocentric glioma report of clinico-pathologic and genetic findings in 8 cases","volume":"31","author":"Preusser","year":"2007"},{"key":"b7-0030197","series-title":"Neuropathology","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1111\/j.1440-1789.2007.00849.x","article-title":"Brain surface spindle cell glioma in a patient with medically intractable partial epilepsy: a variant of monomorphous angiocentric glioma?","volume":"28","author":"Sugita","year":"2008"},{"key":"b8-0030197","series-title":"J Neuropathol Exp Neurol","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1097\/01.jnen.0000182981.02355.10","article-title":"Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma","volume":"64","author":"Wang","year":"2005"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/3\/3\/article-p197.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/3\/3\/article-p197.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/3\/3\/article-p197.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T07:46:31Z","timestamp":1681544791000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/3\/3\/article-p197.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":8,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2008.11.peds0858","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}