{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T22:21:37Z","timestamp":1692915697086},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Myelomeningocele (MMC) is the most complex congenital malformation of the CNS that is compatible with life. Different closure techniques are available for defect reconstruction, but wound healing and tension-free closure of the skin in the midline remain major considerations in large MMCs. In this study, the authors used bilateral proximally based latissimus dorsi (LD) skin island muscle pedicle flaps for closure of large thoracolumbar MMC defects.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Twenty infants with very large thoracolumbar MMCs were enrolled in the study. The mean of age of the patients was 4.1 \u00b1 2.3 months. The width of the MMC was 6 \u00b1 1.2 cm. At operation, 2 triangular V-Y flaps were designed on each side of the defect; the tip of the triangle was extended to the posterior axillary line. The LD flaps based on the thoracodorsal arteries were elevated bilaterally and advanced toward the midline with moderate tension and sutured together. Postoperatively, infants were positioned prone for 7 days and discharged on the 8th day after the operation. They were followed every 2 weeks for evaluation of wound healing.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The wounds healed without any major complication. There was no dehiscence in the postoperative period.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The authors recommended bilateral superiorly based LD skin flaps as an effective method for closure of large thoracolumbar MMC defects. Neural tube defects are among the most common of all human birth defects.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2008.12.peds08226","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T12:27:59Z","timestamp":1253622479000},"page":"331-333","source":"Crossref","is-referenced-by-count":7,"title":["Primary closure of large thoracolumbar myelomeningocele with bilateral latissimus dorsi flaps"],"prefix":"10.3171","volume":"3","author":[{"given":"Mehrdad","family":"Hosseinpour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siamak","family":"Forghani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0030331","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/0007-1226(81)90031-X","article-title":"The use of a latissimus dorsi myocutaneous flap in the repair of spinal defects in spina bifida","volume":"34","author":"Blaiklock","year":"1981"},{"key":"b2-0030331","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.bjps.2003.12.035","article-title":"Large thoracolumbar meningomyelocele defects: incidence and clinical experiences with different modalities of latissimus dorsi musculocutaneus flap","volume":"57","author":"El-khatib","year":"2004"},{"issue":"2","key":"b3-0030331","series-title":"Neurosurg Focus","first-page":"E3","article-title":"Primary closure of open myelomenigocele","volume":"16","author":"Gaskill","year":"2004"},{"key":"b4-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1097\/00006534-199109000-00026","article-title":"Bilateral latissimus dorsi V\u2013Y musculocutaneous flap for closure of a large meningomyelocele","volume":"88","author":"Hayashi","year":"1991"},{"key":"b5-0030331","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1054\/bjps.2001.3680","article-title":"Meningomyelocele reconstruction with bilobed flaps","volume":"54","author":"Lapid","year":"2001"},{"key":"b6-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1097\/00006534-198503000-00015","article-title":"Wound closure of the myelomeningocoele defect","volume":"75","author":"Luce","year":"1985"},{"key":"b7-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1097\/00006534-197808000-00007","article-title":"Repair of major defects of the chest wall and spine with the latissimus dorsi myocutaneous flap","volume":"62","author":"McCraw","year":"1978"},{"key":"b8-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/00006534-198402000-00026","article-title":"Closure of large spina bifida cystica defects with bilateral bipedicled musculocutaneous flaps","volume":"73","author":"Moore","year":"1984"},{"key":"b9-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1097\/00006534-198712000-00007","article-title":"A new surgical approach to closure of large lumbosacral meningomyelocele defects","volume":"80","author":"Ramirez","year":"1987"},{"key":"b10-0030331","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/S0007-1226(03)00115-2","article-title":"Bilateral split latissimus dorsi V\u2013Y flaps for closure of large thoracolumbar meningomyelocele defects","volume":"56","author":"Sarifakioglu","year":"2003"},{"key":"b11-0030331","series-title":"Plast Reconstr Surg","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1097\/00006534-198803000-00025","article-title":"The reverse latissimus dorsi muscle flap for closure of meningomyelocele","volume":"81","author":"Vanderkolk","year":"1988"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/3\/4\/article-p331.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/3\/4\/article-p331.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/3\/4\/article-p331.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T11:51:44Z","timestamp":1681559504000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/3\/4\/article-p331.xml"}},"subtitle":["Technical note"],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":11,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2008.12.peds08226","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}