{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:20:53Z","timestamp":1785147653566,"version":"3.55.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>This study compares the effectiveness of subcutaneous infiltration of a local anesthetic agent (LA) versus intravenous regional anesthesia (IVRA) during endoscopic carpal tunnel release.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Forty-four patients suffering from severe symptoms restricting normal daily activities\u2014such as persistent loss of feeling in the fingers or hand, or no strength in the thumb in spite of prolonged nonsurgical treatment\u2014and with electromyographically proven carpal tunnel syndrome were enrolled in this study. All underwent endoscopic carpal tunnel release. Twenty-two patients had an endoscopic release of the median nerve under LA (LA Group). The other 22 patients underwent the surgery after intravenous induction of regional anesthesia (IVRA Group). The operating room in-out time and tourniquet time were evaluated in both groups. The patients were also asked to evaluate the pain associated with the tourniquet during surgery using a visual analog scale.<\/jats:p>\n<jats:p>The Michigan Hand Outcomes Questionnaire was used to assess the functional outcome preoperatively and at both 2 weeks and 6 months postoperatively.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>One patient in the LA Group needed an additional application of prilocaine, whereas 3 patients in the IVRA Group needed additional LA and 1 of these required propofol. The tourniquet time and operating room time were significantly lower in the LA Group (p = 0.01 for both). There were no complications related to the endoscopic surgery. The Michigan Hand Outcomes Questionnaire did not show significant differences between the groups at either postoperative follow-up examination.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Endoscopic carpal tunnel release with subcutaneous infiltration of LA was well tolerated and effective. Injection-associated problems such as increased thickness of the synovial layer or impaired endoscopic view did not occur.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2008.2.17395","type":"journal-article","created":{"date-parts":[[2010,4,23]],"date-time":"2010-04-23T14:19:33Z","timestamp":1272032373000},"page":"240-244","source":"Crossref","is-referenced-by-count":20,"title":["Subcutaneous local anesthesia versus intravenous regional anesthesia for endoscopic carpal tunnel release: a randomized controlled trial"],"prefix":"10.3171","volume":"114","author":[{"given":"Abdullah","family":"Nabhan","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolf-Ingo","family":"Steudel","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutfi","family":"Dedeman","sequence":"additional","affiliation":[{"name":"Anesthesia, University of Saarland, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehad","family":"Al-Khayat","sequence":"additional","affiliation":[{"name":"Anesthesia, University of Saarland, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basem","family":"Ishak","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns17395","series-title":"J Hand Surg Am","first-page":"987","article-title":"Endoscopic release of the carpal tunnel: a randomized prospective multicenter study","volume":"17","author":"Agee","year":"1992"},{"key":"b2-jns17395","series-title":"J Hand Surg Br","first-page":"395","article-title":"Surgical release of the median nerve under local anaesthesia for carpal tunnel syndrome","volume":"13","author":"Altissimi","year":"1988"},{"key":"b3-jns17395","series-title":"Ann Plast 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for surgical procedures about the elbow","volume":"83","author":"Schroeder","year":"1996"},{"key":"b17-jns17395","series-title":"Can J Anaesth","first-page":"323","article-title":"Anesthesia for carpal tunnel release","volume":"50","author":"Sinha","year":"2003"},{"key":"b18-jns17395","series-title":"Plast Reconstr Surg","first-page":"1184","article-title":"A systematic review of reviews comparing the effectiveness of endoscopic and open carpal tunnel decompression","volume":"113","author":"Thoma","year":"2004"},{"key":"b19-jns17395","series-title":"Reg Anesth","first-page":"175","article-title":"Evaluation of brachial plexus anesthesia for upper extremity surgery","volume":"19","author":"Urban","year":"1994"},{"key":"b20-jns17395","series-title":"J Hand Surg Am","first-page":"438","article-title":"Distal forearm regional block anesthesia for carpal tunnel release","volume":"18","author":"Wilson","year":"1993"},{"key":"b21-jns17395","series-title":"J Hand Surg Br","first-page":"298","article-title":"A local anaesthetic technique for endoscopic carpal tunnel release","volume":"24","author":"Wood","year":"1999"}],"container-title":["Journal of 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