{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:20:38Z","timestamp":1756462838030},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:p>Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing right hemiparesis. Magnetic resonance imaging showed a large homogeneous contrast-enhancing intraventricular midline mass and hydrocephalus. The tumor was completely resected, and histopathological examination revealed plasmacytoma. After postoperative radio- and chemotherapy, vertebral osteolysis was detected as a secondary manifestation of multiple myeloma.<\/jats:p>","DOI":"10.3171\/2008.2.17652","type":"journal-article","created":{"date-parts":[[2008,11,14]],"date-time":"2008-11-14T15:18:18Z","timestamp":1226675898000},"page":"737-739","source":"Crossref","is-referenced-by-count":12,"title":["Multiple myeloma manifesting as an intraventricular brain tumor"],"prefix":"10.3171","volume":"110","author":[{"given":"Joo-Hun David","family":"Eum","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Jeibmann","sequence":"additional","affiliation":[{"name":"Institute of Neuropathology, University Hospital of M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Wiesmann","sequence":"additional","affiliation":[{"name":"Radiology, St. Barbara Hospital, Hamm; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Paulus","sequence":"additional","affiliation":[{"name":"Institute of Neuropathology, University Hospital of M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Ebel","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-17652","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1136\/jnnp.60.1.102","article-title":"Sentinel lesions of primary CNS lymphoma","volume":"60","author":"Alderson","year":"1996"},{"key":"b2-17652","series-title":"Hum Pathol","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/0046-8177(93)90019-D","article-title":"Primary lymphoma of the brain developing in a boy after a 5-year history of encephalitis: polymerase chain reaction and in situ hybridization analyses for Epstein-Barr virus","volume":"24","author":"Aozasa","year":"1993"},{"key":"b3-17652","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1227\/00006123-199506000-00025","article-title":"Solitary dural plasmacytoma: case report","volume":"36","author":"Benli","year":"1995"},{"key":"b4-17652","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"218","DOI":"10.3171\/jns.1995.83.2.0218","article-title":"Management of intracranial plasmacytoma","volume":"83","author":"Bindal","year":"1995"},{"key":"b5-17652","series-title":"Acta Neuropathol","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s00401-007-0258-x","article-title":"Expression pattern and cellular sources of chemokines in primary central nervous system lymphoma","volume":"114","author":"Brunn","year":"2007"},{"key":"b6-17652","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"608","DOI":"10.3171\/jns.2006.104.4.608","article-title":"Dural plasmacytoma revealing multiple myeloma. Case report","volume":"104","author":"Haegelen","year":"2006"},{"key":"b7-17652","series-title":"Am J Hematol","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1002\/ajh.10077","article-title":"Unusual presentation of multiple myeloma with unilateral visual loss and numb chin syndrome in a young adult","volume":"70","author":"Hogan","year":"2002"},{"key":"b8-17652","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1002\/1097-0142(19920315)69:6<1513::AID-CNCR2820690633>3.0.CO;2-X","article-title":"Plasmacytoma. Treatment results and conversion to myeloma","volume":"69","author":"Holland","year":"1992"},{"key":"b9-17652","series-title":"J Clin Oncol","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1200\/JCO.1983.1.4.255","article-title":"Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone","volume":"1","author":"Knowling","year":"1983"},{"key":"b10-17652","series-title":"J Exp Med","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1084\/jem.20041674","article-title":"BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma","volume":"201","author":"Krumbholz","year":"2005"},{"key":"b11-17652","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1002\/ana.410110514","article-title":"Solitary intracranial plasmacytoma: two patients with extended follow-up","volume":"11","author":"Krumholz","year":"1982"},{"key":"b12-17652","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1002\/1097-0142(19870415)59:8<1475::AID-CNCR2820590814>3.0.CO;2-2","article-title":"Solitary plasmacytomas of bone and extramedullary plasmacytomas. A clinicopathologic and immunohistochemical study","volume":"59","author":"Meis","year":"1987"},{"key":"b13-17652","series-title":"Ann Hematol","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1007\/s00277-001-0387-6","article-title":"Meningeal and cerebral involvement in multiple myeloma patients","volume":"80","author":"Patriarca","year":"2001"},{"key":"b14-17652","series-title":"Acta Neuropathol","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1007\/BF00369448","article-title":"Comparison of integrin adhesion molecules expressed by primary brain lymphomas and nodal lymphomas","volume":"86","author":"Paulus","year":"1993"},{"key":"b15-17652","series-title":"J Clin Pathol","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1136\/jcp.53.5.398","article-title":"Myelomatous involvement of the dura mater: a rare complication of multiple myeloma","volume":"53","author":"Roddie","year":"2000"},{"key":"b16-17652","series-title":"Neurosurgery","first-page":"1039","article-title":"Association between intracranial plasmacytoma and multiple myeloma: clinicopathological outcome study","volume":"49","author":"Schwartz","year":"2001"},{"key":"b17-17652","series-title":"Blood","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1182\/blood-2002-05-1576","article-title":"Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma","volume":"101","author":"Smith","year":"2003"},{"key":"b18-17652","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/S1042-3680(03)00060-3","article-title":"Epidemiology and pathology of intraventricular tumors","volume":"14","author":"Waldron","year":"2003"},{"key":"b19-17652","series-title":"Skull Base","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1055\/s-2002-31570-1","article-title":"Plasma cell tumors of the skull base: four case reports and literature review","volume":"12","author":"Wein","year":"2002"},{"key":"b20-17652","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1227\/00006123-199011000-00026","article-title":"Intracerebral solitary plasmacytoma","volume":"27","author":"Wisniewski","year":"1990"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p737.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p737.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p737.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T05:21:26Z","timestamp":1664169686000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p737.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":20,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2008.2.17652","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}