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Patients were investigated prospectively, treated, and then assessed periodically with respect to pain relief and neurological function. Complete pain relief was achieved initially after all 3 interventions. The first patient was pain free without medication for 2 months after the first treatment (60 Gy) and for 4 months after the second treatment (70 Gy). The second patient (treated with 75 Gy) was still pain free without medication at the last follow-up (12 months). Neither patient had any neurological complications. The initial response of GPN to low-dose GKS was favorable, but symptoms may recur. No adverse neurological effects were observed in any of the lower cranial nerves. It will be necessary to investigate the optimal radiation dose and target of GKS for achieving long-term pain relief in GPN.<\/jats:p>","DOI":"10.3171\/2008.8.17641","type":"journal-article","created":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T18:00:41Z","timestamp":1227290441000},"page":"559-563","source":"Crossref","is-referenced-by-count":41,"title":["Gamma Knife surgery for glossopharyngeal neuralgia"],"prefix":"10.3171","volume":"110","author":[{"given":"Shoji","family":"Yomo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser","family":"Arkha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Donnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"R\u00e9gis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1100559","series-title":"Electroencephalogr Clin Neurophysiol","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/0013-4694(86)90089-1","article-title":"Mechanisms of syncope in glossopharyngeal neuralgia","volume":"63","author":"Barbash","year":"1986"},{"key":"b2-1100559","series-title":"Med Clin North Am","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/S0025-7125(16)30436-9","article-title":"Diagnosis and treatment of cranial neuralgias","volume":"75","author":"Dalessio","year":"1991"},{"key":"b3-1100559","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1227\/00006123-199501000-00007","article-title":"Glossopharyngeal neuralgia with cardiac syncope","volume":"36","author":"Ferrante","year":"1995"},{"key":"b4-1100559","series-title":"Neurol Clin","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/S0733-8619(18)30377-3","article-title":"Clinical pharmacology of drugs used to treat head and face pain","volume":"8","author":"Fromm","year":"1990"},{"key":"b5-1100559","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"952","DOI":"10.3171\/jns.1984.61.5.0952","article-title":"Surgical treatment of glossopharyngeal neuralgia and pain from cancer of the nasopharynx. 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