{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:43:44Z","timestamp":1790873024349,"version":"4.1.0"},"reference-count":17,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The aim of this study was to provide information to help confirm the diagnosis of trigeminal neuralgia (TN) using MR imaging.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors evaluated atrophy of the trigeminal nerve, the cross-sectional area of the cerebellopontine angle (CPA) cistern, and the length of the cisternal segment of the trigeminal nerve on the affected side in 26 consecutive patients with TN who were treated using Gamma Knife surgery.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The mean volume of the trigeminal nerve on the affected side was significantly smaller than the mean volume of the trigeminal nerve on the unaffected side (p &lt; 0.001). Nerve atrophy was present in 25 patients (96.2%) on the affected side and in 1 patient on the unaffected side. The mean cross-sectional area of the CPA cistern on the affected side (188.5 mm2) was significantly smaller than the mean volume on the unaffected side (232.8 mm2) in 25 of the 26 patients (p = 0.001). The mean length of the cisternal segment of the trigeminal nerve on the affected side (7.9 mm) was significantly shorter than the mean length on the unaffected side (9.6 mm) in 25 of the 26 patients (p = 0.001).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Among the patients with TN, there was a statistically significant difference in the MR imaging findings of the affected side compared with the unaffected side of the trigeminal nerve. Atrophy of the trigeminal nerve and a small CPA cistern in patients with TN provides additional markers for the diagnosis of TN and helps confirm the diagnosis based on clinical examination.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2008.8.jns08522","type":"journal-article","created":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T15:15:47Z","timestamp":1225466147000},"page":"633-637","source":"Crossref","is-referenced-by-count":43,"title":["Nerve atrophy and a small cerebellopontine angle cistern in patients with trigeminal neuralgia"],"prefix":"10.3171","volume":"110","author":[{"given":"Seong-Hyun","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Kyoo","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaechan","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Hyun","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Suk","family":"Hamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-08522","series-title":"Neurosurgery","first-page":"956","article-title":"Preoperative evaluation of neurovascular compression in patients with trigeminal neuralgia by use of three-dimensional reconstruction from two types of high resolution magnetic resonance imaging","volume":"51","author":"Akimoto","year":"2002"},{"key":"b2-08522","series-title":"J Neurosurg","first-page":"359","article-title":"Evaluation of microvascular decompression and partial sensory rhizotomy in 252 cases of trigeminal neuralgia","volume":"70","author":"Bederson","year":"1989"},{"key":"b3-08522","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"532","DOI":"10.3171\/jns.2002.96.3.0532","article-title":"Mechanism of trigeminal neuralgia: an ultrastructual analysis of trigeminal root specimens obtained during microvascular decompression surgery","volume":"96","author":"Devor","year":"2002"},{"key":"b4-08522","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1148\/radiol.2382042214","article-title":"Nerve atrophy in severe trigeminal neuralgia: noninvasive confirmation at MR imaging\u2014initial experience","volume":"238","author":"Erbay","year":"2006"},{"key":"b5-08522","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1212\/01.wnl.0000256340.16766.1d","article-title":"Loss of anisotropy in trigeminal neuralgia revealed by diffusion tensor imaging","volume":"68","author":"Herweh","year":"2007"},{"key":"b6-08522","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"159","DOI":"10.3171\/jns.1967.26.1part2.0159","article-title":"Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia","volume":"26","author":"Jannetta","year":"1967"},{"key":"b7-08522","series-title":"Neursurgery","first-page":"101","article-title":"Imaging the trigeminal nerve and pons before and after surgical intervention for trigeminal neuralgia","volume":"48","author":"Jawahar","year":"2001"},{"key":"b8-08522","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"483","DOI":"10.3171\/JNS\/2008\/108\/3\/0483","article-title":"Anatomical study of the trigeminal and facial nerves with the aid of 3.0-tesla magnetic resonance imaging","volume":"108","author":"Kakizawa","year":"2008"},{"key":"b9-08522","series-title":"J Korean Neurosurg Soc","first-page":"148","article-title":"Anatomical considerations in gamma knife radiosurgery for idiopathic trigeminal neuralgia","volume":"40","author":"Kim","year":"2006"},{"key":"b10-08522","series-title":"AJNR Am J Neuroradiol","first-page":"1635","article-title":"MR imaging of traumatic lesions of the inferior alveolar nerve in patients with fracture of the mandible","volume":"24","author":"Kress","year":"2003"},{"key":"b11-08522","series-title":"Eur Radiol","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1007\/s00330-005-2674-4","article-title":"MRI volumetry for the preoperative diagnosis of trigeminal neuralgia","volume":"15","author":"Kress","year":"2005"},{"key":"b12-08522","series-title":"Brain Pathol","first-page":"1","article-title":"Central demyelination of the Vth nerve root in trigeminal neuralgia associated with vascular compression","volume":"8","author":"Love","year":"1998"},{"key":"b13-08522","series-title":"Radiol Med (Torino)","first-page":"700","article-title":"Magnetic resonance in trigeminal neuralgia","volume":"83","author":"Magnaldi","year":"1992"},{"key":"b14-08522","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1999.90.1.0001","article-title":"Microvascular decompression of cranial nerves: lessons learned after 4400 operations","volume":"90","author":"McLaughlin","year":"1999"},{"key":"b15-08522","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1227\/01.NEU.0000228924.20750.D4","article-title":"Volumetric measurement of the pontomesencephalic cistern in patients with trigeminal neuralgia and healthy controls","volume":"59","author":"Rasche","year":"2006"},{"key":"b16-08522","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s701-002-8269-4","article-title":"Anatomical observations during microvascular decompression for idiopathic trigeminal neuralgia (with correlations between topography of pain and site of the neurovascular conflict). Prospecitve study in a series of 579 patients","volume":"144","author":"Sindou","year":"2002"},{"key":"b17-08522","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3171\/jns.1982.57.1.0014","article-title":"Decompression of the posterior trigeminal root in trigeminal neuralgia, a 30-year follow-up review","volume":"57","author":"Taarnhoj","year":"1982"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p633.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p633.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p633.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T04:59:19Z","timestamp":1664168359000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p633.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":17,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2008.8.jns08522","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}