{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:48:49Z","timestamp":1792176529691,"version":"4.4.0"},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>Microvascular decompression (MVD) is an effective treatment for trigeminal neuralgia (TN). However, many patients do not experience complete pain relief, and relapse can occur even after an initial excellent result. This study was designed to identify characteristics associated with improved long-term outcome after MVD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred seventy-nine consecutive patients who had undergone MVD for TN at the authors' institution were contacted, and 95 were enrolled in the study. Patients provided information about preoperative pain characteristics including preponderance of shock-like (Type 1 TN) or constant (Type 2 TN) pain, preoperative duration, trigger points, anticonvulsant therapy response, memorable onset, and pain-free intervals. Three groups were defined based on outcome: 1) excellent, pain relief without medication; 2) good, mild or intermittent pain controlled with low-dose medication; and 3) poor, severe persistent pain or need for additional surgical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Type of TN pain (Type 1 TN vs Type 2 TN) was the only significant predictor of outcome after MVD. Results were excellent, good, and poor for Type 1 TN versus Type 2 TN patients in 60 versus 25%, 24 versus 39%, and 16 versus 36%, respectively. Among patients with each TN type, there was a significant trend toward better outcome with greater proportional contribution of Type 1 TN (lancinating) symptoms (p &lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pain relief after MVD is strongly correlated with the lancinating pain component, and therefore type of TN pain is the best predictor of long-term outcome after MVD. Application of this information should be helpful in the selection of TN patients likely to benefit from MVD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2008.9.17660","type":"journal-article","created":{"date-parts":[[2009,2,20]],"date-time":"2009-02-20T10:06:05Z","timestamp":1235124365000},"page":"620-626","source":"Crossref","is-referenced-by-count":79,"title":["Predictors of long-term success after microvascular decompression for trigeminal neuralgia"],"prefix":"10.3171","volume":"110","author":[{"given":"Jonathan P.","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen T.","family":"Magill","sequence":"additional","affiliation":[{"name":"School of Medicine, Oregon Health & Science University, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feridun","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim J.","family":"Burchiel","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-17660","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1056\/NEJM199604253341701","article-title":"The long-term outcome of microvascular decompression for trigeminal neuralgia","volume":"334","author":"Barker","year":"1996"},{"key":"b2-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"674","DOI":"10.3171\/jns.1980.53.5.0674","article-title":"Abnormal impulse generation in focally demyelinated trigeminal roots","volume":"53","author":"Burchiel","year":"1980"},{"key":"b3-17660","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1227\/01.NEU.0000088806.11659.D8","article-title":"A new classification for facial pain","volume":"53","author":"Burchiel","year":"2003"},{"key":"b4-17660","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1093\/neurosurgery\/46.1.152","article-title":"On the natural history of trigeminal neuralgia","volume":"46","author":"Burchiel","year":"2000"},{"key":"b5-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"532","DOI":"10.3171\/jns.2002.96.3.0532","article-title":"Mechanism of trigeminal neuralgia: an ultrastructural analysis of trigeminal root specimens obtained during microvascular decompression surgery","volume":"96","author":"Devor","year":"2002"},{"key":"b6-17660","series-title":"Semin Neurosurg","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1055\/s-2004-830014","article-title":"Trigeminal neuralgia and other craniofacial pain syndromes: an overview","volume":"15","author":"Elias","year":"2004"},{"issue":"5","key":"b7-17660","series-title":"Neurosurg Focus","first-page":"E3","article-title":"Trigeminal neuralgia: definition and classification","volume":"18","author":"Eller","year":"2005"},{"key":"b8-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"381","DOI":"10.3171\/jns.1980.52.3.0381","article-title":"Microvascular relations of the trigeminal nerve. An anatomical study with clinical correlation","volume":"52","author":"Haines","year":"1980"},{"key":"b9-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"948","DOI":"10.3171\/jns.1992.76.6.0948","article-title":"Neurovascular compression in trigeminal neuralgia: a clinical and anatomical study","volume":"76","author":"Hamlyn","year":"1992"},{"issue":"Suppl","key":"b10-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"159","DOI":"10.3171\/jns.1967.26.1part2.0159","article-title":"Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia","volume":"26","author":"Jannetta","year":"1967"},{"key":"b11-17660","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1212\/WNL.51.6.1641","article-title":"Recovery of nerve conduction following microvascular decompression for trigeminal neuralgia","volume":"51","author":"Leandri","year":"1998"},{"key":"b12-17660","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.surneu.2004.02.028","article-title":"Trigeminal neuralgia: what are the important factors for good operative outcomes with microvascular decompression","volume":"62","author":"Li","year":"2004"},{"key":"b13-17660","series-title":"Br J Anaesth","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/bja\/87.1.117","article-title":"Trigeminal neuralgia\u2014pathophysiology, diagnosis and current treatment","volume":"87","author":"Nurmikko","year":"2001"},{"key":"b14-17660","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"527","DOI":"10.3171\/jns.2002.96.3.0527","article-title":"Predictors of outcome in surgically managed patients with typical and atypical trigeminal neuralgia: comparison of results following microvascular decompression","volume":"96","author":"Tyler-Kabara","year":"2002"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p620.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p620.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/110\/4\/article-p620.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:58:31Z","timestamp":1664153911000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/110\/4\/article-p620.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":14,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2008.9.17660","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1157806.619035","asserted-by":"object"}]},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}