{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T19:56:16Z","timestamp":1785527776147,"version":"3.56.0"},"reference-count":10,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>Cerebrospinal fluid overproduction resulting in communicating hydrocephalus is observed in patients who have choroid plexus papilloma or choroid plexus carcinoma. Less often, patients with these conditions have diffuse villous hyperplasia. Prior studies report CSF production greater than 3 L per day in these patients. These patients are treated with CSF shunting or by either unilateral choroid plexectomy or staged bilateral choroid plexectomy. The authors present a patient who had a number of congenital anomalies and a karyotype that revealed balanced translocations, 5 to 7 and 9 to 11. She presented with hydrocephalus and had CSF production of 5 L per day, greater output than ever previously reported. She was treated with a single-stage bilateral choroid plexectomy. Histopathological analysis revealed a bilateral choroid plexus papilloma. Postoperatively, the patient responded well clinically and showed radiographic improvement of her hydrocephalus. Bilateral choroid plexus papilloma has been reported in the literature as a cause for neonatal and congenital hydrocephalus. It can result in high CSF output and can be successfully treated with a single-stage bilateral choroid plexectomy. Further studies are ongoing to identify genes involved in embryogenesis of the choroid plexus.<\/jats:p>","DOI":"10.3171\/2009.10.peds08454","type":"journal-article","created":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T13:57:26Z","timestamp":1270130246000},"page":"342-345","source":"Crossref","is-referenced-by-count":29,"title":["Single-stage bilateral choroid plexectomy for choroid plexus papilloma in a patient presenting with high cerebrospinal fluid output"],"prefix":"10.3171","volume":"5","author":[{"given":"Shahid M.","family":"Nimjee","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciaran J.","family":"Powers","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger E.","family":"McLendon","sequence":"additional","affiliation":[{"name":"Department of Pathology, Duke University Medical Center, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald A.","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert E.","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0050342","series-title":"Pediatr Radiol","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s00247-005-1456-0","article-title":"Diffuse choroid plexus hyperplasia: an under-diagnosed cause of hydrocephalus in children?","volume":"35","author":"Aziz","year":"2005"},{"key":"b2-0050342","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"689","DOI":"10.3171\/jns.1996.85.4.0689","article-title":"Hydrocephalus secondary to diffuse villous hyperplasia of the choroid plexus. 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Case report","volume":"107","author":"Smith","year":"2007"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/5\/4\/article-p342.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/5\/4\/article-p342.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/5\/4\/article-p342.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T12:35:58Z","timestamp":1681562158000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/5\/4\/article-p342.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":10,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2009.10.peds08454","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}