{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T14:17:47Z","timestamp":1781619467354,"version":"3.54.5"},"reference-count":42,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The aim of this study was to identify patients likely to develop CSF leaks after vestibular schwannoma surgery using a retrospective analysis for the identification of risk factors.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Between January 2001 and December 2006, 420 patients underwent retrosigmoidal microsurgical tumor removal in a standardized procedure. Of these 420 patients, 363 underwent treatment for the first time, and 27 suffered from recurrent tumors. Twenty-six patients had bilateral tumors due to neurofibromatosis Type 2, and 4 patients had previously undergone radiosurgical treatment. An analysis was performed to examine the incidence of postoperative CSF fistulas in all 4 groups.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The incidence of CSF leakage was higher in the tumor recurrence group (11.1%) than in patients undergoing surgery for the first time (4.4%). There were no CSF fistulas in the neurofibromatosis Type 2 group or in patients with preoperative radiosurgical treatment. Tumor size was identified as a possible risk factor in a previous study.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Surgery for recurrent tumors is a significant risk factor for the development of CSF leaks.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2009.2.jns081380","type":"journal-article","created":{"date-parts":[[2009,3,30]],"date-time":"2009-03-30T12:24:22Z","timestamp":1238415862000},"page":"874-883","source":"Crossref","is-referenced-by-count":37,"title":["Factors affecting postoperative cerebrospinal fluid leaks after retrosigmoidal craniotomy for vestibular schwannomas"],"prefix":"10.3171","volume":"111","author":[{"given":"Lennart H.","family":"Stieglitz","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten H.","family":"Wrede","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Gharabaghi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Eberhardt Karls University, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venelin M.","family":"Gerganov","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Samii","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madjid","family":"Samii","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolf O.","family":"Luedemann","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, International Neuroscience Institute, Hannover; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1110874","series-title":"J Neurosurg","first-page":"347","article-title":"Reduction of cerebrospinal fluid rhinorrhea after vestibular schwannoma surgery by reconstruction of the drilled porus acusticus with hydroxyapatite bone cement","volume":"107","author":"Baird","year":"2007"},{"key":"b2-1110874","series-title":"Acta Neurochir (Wien)","first-page":"979","article-title":"Incidence of cerebrospinal fluid leak after microsurgical removal of vestibular schwannomas","volume":"144","author":"Bani","year":"2002"},{"key":"b3-1110874","series-title":"Otol Neurotol","first-page":"107","article-title":"Cerebrospinal fluid leak after acoustic neuroma surgery: a comparison of 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