{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T09:00:27Z","timestamp":1780736427616,"version":"3.54.1"},"reference-count":68,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>Intracranial aneurysms may grow closer to anterior optic pathways, causing mass effect over these anatomical structures, including visual deficit. The authors retrospectively reviewed a series of aneurysms in patients presenting with visual field deficit caused by mass effect, to analyze the aneurysm's characteristics, the neurosurgical management of these aneurysms, as well as their clinical, visual, and radiological outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The authors reviewed the medical charts, neuroimaging examination results, and surgical videos of 15 patients presenting with visual symptoms caused by an aneurysm's mass effect over the anterior optic pathways. These patients were treated at the Department of Neurosurgery, Center of Neurology and Neurosurgery Associates, Hospital Benefic\u00eancia Portuguesa de S\u00e3o Paulo, Brazil. Statistical analysis was performed to identify the variables related to partial or total recovery of the visual symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients underwent microsurgical clip placement and emptying of their aneurysms. After a mean follow-up of 38.5 months, the mean postoperative Glasgow Outcome Scale score was 4.33, and the visual outcomes were as follows: 1 patient (6.6%) unchanged, 7 (46.6%) improved, and 7 (46.6%) experienced complete recovery from visual deficits. The variables that influenced the visual outcomes were the size of the aneurysm (p = 0.039), duration of the visual symptoms (p = 0.002), aneurysm wall calcification (p = 0.010), and intraluminal thrombosis (p = 0.007). Postoperative examination using digital subtraction angiography showed complete aneurysm occlusion in 14 (93.3%) of the 15 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Intracranial aneurysms causing mass effect over the anterior optic pathways usually present with complex features. The best treatment option must include not only the aneurysm occlusion but also relief of the mass effect. Microsurgical clip placement with reduction of aneurysmal mass effect achieved improvement in visual ability or recovery from visual impairment, as well as total aneurysm occlusion, in 93.3% of the study group. Therefore, this option is well supported as the first choice of treatment for intracranial aneurysms presenting with mass effect over the anterior visual pathways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2009.3.focus0924","type":"journal-article","created":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T09:57:26Z","timestamp":1241171846000},"page":"E3","source":"Crossref","is-referenced-by-count":46,"title":["Intracranial aneurysms presenting with mass effect over the anterior optic pathways: neurosurgical management and outcomes"],"prefix":"10.3171","volume":"26","author":[{"given":"Jean G.","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A. B.","family":"Borba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziz","family":"Rassi-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel M.","family":"de Moura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago L.","family":"Sanchez-J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio S.","family":"Rassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Vanderlei M.","family":"de Holanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Giudicissi-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0260003","series-title":"Surg Neurol","first-page":"41","article-title":"Carotid-ophthalmic aneurysms","volume":"5","author":"Almeida","year":"1976"},{"key":"b2-0260003","series-title":"Surg Neurol","first-page":"8","article-title":"Giant intracranial aneurysm surgery: the role of microvascular reconstruction","volume":"34","author":"Ausman","year":"1990"},{"key":"b3-0260003","series-title":"Acta Neurol Scand","first-page":"204","article-title":"Compression of the visual pathway by anterior cerebral artery aneurysm","volume":"99","author":"Bakker","year":"1999"},{"key":"b4-0260003","series-title":"Neurosurg Clin N Am","first-page":"435","article-title":"Epidemiology and clinical presentation of aneurysmal subarachnoid hemorrhage","volume":"9","author":"Becker","year":"1998"},{"key":"b5-0260003","series-title":"Neurosurg Clin N Am","first-page":"631","article-title":"Aneurysms and subarachnoid hemorrhage","volume":"10","author":"Biousse","year":"1999"},{"key":"b6-0260003","series-title":"J Neurosurg","first-page":"855","article-title":"Surgical and endovascular management of symptomatic posterior circulation fusiform aneurysms","volume":"106","author":"Coert","year":"2007"},{"key":"b7-0260003","series-title":"Clin Neurol Neurosurg","first-page":"259","article-title":"Cerebral aneurysms causing visual symptoms: their features and surgical outcome","volume":"100","author":"Date","year":"1998"},{"key":"b8-0260003","series-title":"J Neurosurg","first-page":"24","article-title":"Carotid-ophthalmic aneurysms","volume":"29","author":"Drake","year":"1968"},{"key":"b9-0260003","series-title":"Neurosurgery","first-page":"1385","article-title":"Carotid-ophtalmic Aneurysms","volume":"Vol 2","author":"Ferguson","year":"1985"},{"key":"b10-0260003","series-title":"Surg Neurol","first-page":"1","article-title":"Carotid-ophthalmic aneurysms: visual abnormalities in 32 patients and the results of treatment","volume":"16","author":"Ferguson","year":"1981"},{"key":"b11-0260003","series-title":"Am J Ophthalmol","first-page":"283","article-title":"Optic tract compression from dolichoectatic basilar artery","volume":"132","author":"Guirgis","year":"2001"},{"key":"b12-0260003","series-title":"Neurosurgery","first-page":"1304","article-title":"Complex intracranial aneurysms: combined operative and endovascular approaches","volume":"43","author":"Hacein-Bey","year":"1998"},{"key":"b13-0260003","series-title":"J Neurosurg","first-page":"659","article-title":"The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect","volume":"80","author":"Halbach","year":"1994"},{"key":"b14-0260003","series-title":"J Neurosurg","first-page":"968","article-title":"Large ophthalmic segment aneurysms with anterior optic pathway compression: assessment of anatomical and visual outcomes after endosaccular coil therapy","volume":"106","author":"Heran","year":"2007"},{"key":"b15-0260003","series-title":"J Neurosurg","first-page":"857","article-title":"Endovascular detachable balloon embolization therapy of cavernous carotid artery aneurysms: results in 87 cases","volume":"72","author":"Higashida","year":"1990"},{"key":"b16-0260003","series-title":"Neurosurgery","first-page":"703","article-title":"Giant anterior communicating artery aneurysm with bitemporal hemianopia: case report","volume":"8","author":"Hojer-Pedersen","year":"1981"},{"key":"b17-0260003","series-title":"J Neurosurg","first-page":"916","article-title":"Progressive perianeurysmal edema induced after endovascular coil embolization. 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Neurosurg","first-page":"24","article-title":"Carotid-ophthalmic aneurysms","volume":"29","author":"Drake","year":"1968"},{"key":"b9-0260003","series-title":"Neurosurgery","first-page":"1385","article-title":"Carotid-ophtalmic Aneurysms","volume":"Vol 2","author":"Ferguson","year":"1985"},{"key":"b10-0260003","series-title":"Surg Neurol","first-page":"1","article-title":"Carotid-ophthalmic aneurysms: visual abnormalities in 32 patients and the results of treatment","volume":"16","author":"Ferguson","year":"1981"},{"key":"b11-0260003","series-title":"Am J Ophthalmol","first-page":"283","article-title":"Optic tract compression from dolichoectatic basilar artery","volume":"132","author":"Guirgis","year":"2001"},{"key":"b12-0260003","series-title":"Neurosurgery","first-page":"1304","article-title":"Complex intracranial aneurysms: combined operative and endovascular approaches","volume":"43","author":"Hacein-Bey","year":"1998"},{"key":"b13-0260003","series-title":"J Neurosurg","first-page":"659","article-title":"The efficacy of endosaccular aneurysm occlusion in alleviating neurological deficits produced by mass effect","volume":"80","author":"Halbach","year":"1994"},{"key":"b14-0260003","series-title":"J Neurosurg","first-page":"968","article-title":"Large ophthalmic segment aneurysms with anterior optic pathway compression: assessment of anatomical and visual outcomes after endosaccular coil therapy","volume":"106","author":"Heran","year":"2007"},{"key":"b15-0260003","series-title":"J Neurosurg","first-page":"857","article-title":"Endovascular detachable balloon embolization therapy of cavernous carotid artery aneurysms: results in 87 cases","volume":"72","author":"Higashida","year":"1990"},{"key":"b16-0260003","series-title":"Neurosurgery","first-page":"703","article-title":"Giant anterior communicating artery aneurysm with bitemporal hemianopia: case report","volume":"8","author":"Hojer-Pedersen","year":"1981"},{"key":"b17-0260003","series-title":"J Neurosurg","first-page":"916","article-title":"Progressive perianeurysmal edema induced after endovascular coil embolization. Report of three cases and review of the literature","volume":"106","author":"Horie","year":"2007"},{"key":"b18-0260003","series-title":"Surg Neurol","first-page":"532","article-title":"Computed tomographic demonstration of the effect of proximal parent artery ligation for giant intracranial aneurysms","volume":"19","author":"Ishii","year":"1983"},{"key":"b19-0260003","series-title":"Neurosurgery","first-page":"26","article-title":"Treatment of aneurysms of the internal carotid artery by intravascular balloon occlusion: long-term follow-up of 58 patients","volume":"36","author":"Larson","year":"1995"},{"key":"b20-0260003","series-title":"Neurol Clin","first-page":"323","article-title":"Acute visual loss and other disorders of the eyes","volume":"16","author":"Laskowitz","year":"1998"},{"key":"b21-0260003","series-title":"J Neurosurg","first-page":"956","article-title":"Unruptured aneurysms presenting with mass effect symptoms: response to endosaccular treatment with Guglielmi detachable coils. 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