{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:11:41Z","timestamp":1758478301133},"reference-count":8,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2009,9]]},"abstract":"\nObject<\/jats:title>\nFive to ten percent of pediatric brain tumors are located in the ventricles. Among them, forniceal lesions are rare and their management has not often been described. The aim of this study was to review the clinical, radiological, and histopathological features as well as the feasibility of surgical excision and the outcomes in these patients.<\/jats:p><\/jats:sec>\n\nMethods<\/jats:title>\nFrom a retrospective analysis of 250 cases of supratentorial pediatric glioma, the records of 8 children presenting with forniceal lesions were selected and reviewed.<\/jats:p><\/jats:sec>\n\nResults<\/jats:title>\nThe median age of patients in the cohort was 13.5 years. Presenting features included intracranial hypertension (7 cases), hypothalamic dysfunction (2), and memory dysfunction (3). Complete resection was possible in only 1 case, where the lesion was mainly exophytic; the remaining patients had either a partial resection or biopsy. On histological review, the tumors were confirmed as pilocytic astrocytoma (4 lesions), WHO Grade II astrocytoma (3), and ganglioglioma (1). Postoperatively, working and retrograde memory was normal for all patients, but the authors found a mild alteration in verbal episodic memory in 5 patients. Despite fatigability for 5 patients, academic achievement was normal for all but 2, both of whom had preoperative school difficulties. Additional treatment was required for 5 patients for tumor progression, with a median interval of 19 months from surgery. At a median follow-up duration of 4.9 years, all patients had stable disease.<\/jats:p><\/jats:sec>\n\nConclusions<\/jats:title>\nIn this series, forniceal gliomas were found to be low-grade gliomas. They are surgically challenging, and only exophytic lesions may be cured surgically. Due to the high rate of progression of residual disease, adjuvant therapy is recommended for infiltrative tumors, and it yielded excellent results.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2009.4.peds08472","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T12:21:19Z","timestamp":1253622079000},"page":"249-253","source":"Crossref","is-referenced-by-count":7,"title":["Forniceal glioma in children"],"prefix":"10.3171","volume":"4","author":[{"given":"Thomas","family":"Blauwblomme","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascale","family":"Varlet","sequence":"additional","affiliation":[{"name":"Department of Pathology, H\u00f4pital Sainte-Anne, Universit\u00e9 Paris Descartes, Paris;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Goodden","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Alder Hey Children's National Health Service Foundation Trust, Liverpool, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie Laure","family":"Cuny","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helene","family":"Piana","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Roujeau","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"DiRocco","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Grill","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology, Institut Gustave Roussy, Villejuif, France; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginie","family":"Kieffer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology, Institut Gustave Roussy, Villejuif, France; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Boddaert","sequence":"additional","affiliation":[{"name":"Neuroradiology, H\u00f4pital Necker Enfants Malades, Universit\u00e9 Paris Descartes;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Sainte-Rose","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Puget","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0040249","series-title":"Brain","doi-asserted-by":"publisher","first-page":"2611","DOI":"10.1093\/brain\/114.6.2611","article-title":"Amnesia in man following transection of the fornix. A review","volume":"114","author":"Gaffan","year":"1991"},{"key":"b2-0040249","series-title":"Neurochirurgie","first-page":"247","article-title":"[Fornix and septal tumor (author's transl).]","volume":"26","author":"Laine","year":"1980"},{"key":"b3-0040249","series-title":"Acta Neuropathol","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00401-007-0243-4","article-title":"The 2007 WHO classification of tumours of the central nervous system","volume":"114","author":"Louis","year":"2007"},{"key":"b4-0040249","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1054\/jocn.2000.0910","article-title":"Tumours around the foramen of Monro: clinical and neuroimaging features and their differential diagnosis","volume":"9","author":"Nishio","year":"2002"},{"issue":"6","key":"b5-0040249","series-title":"Neurosurg Focus","first-page":"E4","article-title":"Pediatric supratentorial intraventricular tumors","volume":"10","author":"Suh","year":"2001"},{"key":"b6-0040249","series-title":"J Neurosci","doi-asserted-by":"publisher","first-page":"12868","DOI":"10.1523\/JNEUROSCI.3536-07.2007","article-title":"Fornix transection impairs learning of randomly changing object discriminations","volume":"27","author":"Wilson","year":"2007"},{"key":"b7-0040249","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1097\/00006123-199705000-00020","article-title":"The transcallosal interforniceal approach to the third ventricle: anatomic and microsurgical aspects","volume":"40","author":"Winkler","year":"1997"},{"key":"b8-0040249","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1007\/s003810050470","article-title":"Lateral ventricle tumors in children: a series of 54 cases","volume":"15","author":"Zuccaro","year":"1999"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/4\/3\/article-p249.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/4\/3\/article-p249.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/4\/3\/article-p249.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T11:34:35Z","timestamp":1681558475000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/4\/3\/article-p249.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":8,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2009.4.peds08472","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}