{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:38:19Z","timestamp":1783777099434,"version":"3.55.0"},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p>The treatment of the transsphenoidal sphenopalatine encephalocele in infants has not been thoroughly described in the literature. Pterional and subfrontal transbasal approaches have been reported as the advised treatment for transethmoidal encephalocele, but their feasibility for transsphenoidal encephalocele remains controversial, particularly in neonates. The potential harm to vital structures within the herniated tissue and intraoperative bleeding have been considered the major cause of poor postoperative results.<\/jats:p>\n<jats:p>The authors present the case of a full-term newborn with a cleft palate and a large transsphenoidal sphenopalatine encephalocele, which filled the nasopharyngeal space and provided MR imaging evidence of an intralesional pituitary gland.<\/jats:p>\n<jats:p>The lesion is unusual, and the extracranial intraoral endoscopic approach with an optimal outcome and sparing of the pituitary tissue has never been described in detail in an infant of this age.<\/jats:p>","DOI":"10.3171\/2009.4.peds0884","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T12:21:19Z","timestamp":1253622079000},"page":"262-265","source":"Crossref","is-referenced-by-count":10,"title":["Combined endoscopic-microsurgical approach for transsphenoidal (sphenopalatine) encephalocele with an intralesional pituitary gland"],"prefix":"10.3171","volume":"4","author":[{"given":"Roberto","family":"Faggin","sequence":"first","affiliation":[{"name":"Divisions of Pediatric Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Pentimalli","sequence":"additional","affiliation":[{"name":"Divisions of Pediatric Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizia","family":"Grazzini","sequence":"additional","affiliation":[{"name":"Anesthesiology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Saetti","sequence":"additional","affiliation":[{"name":"Airway Endoscopic Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Drigo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"d'Avella","sequence":"additional","affiliation":[{"name":"Divisions of Pediatric Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0040262","series-title":"Arch Otolaryngol","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1001\/archotol.1965.00760010529015","article-title":"Intranasal encephaloceles","volume":"82","author":"Blumenfeld","year":"1965"},{"key":"b2-0040262","series-title":"Acta Otolaryngol","doi-asserted-by":"publisher","first-page":"519","DOI":"10.3109\/00016484709123765","article-title":"Intranasal forms of encephalomeningocele","volume":"35","author":"Gisselsson","year":"1947"},{"key":"b3-0040262","series-title":"Ann Otol Rhinol Laryngol","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1177\/000348940311201011","article-title":"Intrasphenoidal transsellar encephalocele repaired by endoscopic approach","volume":"112","author":"Herman","year":"2003"},{"key":"b4-0040262","series-title":"Zh Vopr Neirokhir Im N N Burdenko","first-page":"26","article-title":"[Endoscopic endonasal diagnosis and treatment of basal liquorrhea and encephalocele of the anterior regions of the skull base.]","volume":"1","author":"Kapitanov","year":"2002"},{"key":"b5-0040262","series-title":"Ann Otol Rhinol Laryngol","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1177\/000348948509400522","article-title":"Transsphenoidal encephalocele","volume":"94","author":"Kenna","year":"1985"},{"key":"b6-0040262","series-title":"Disorders of the Developing Nervous System: Diagnosis and Treatment","first-page":"153","article-title":"Encephalocele and related anomalies","author":"McLaurin","year":"1986"},{"key":"b7-0040262","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1055\/s-2004-818522","article-title":"Endoscopic treatment of encephaloceles of the lateral wall of the sphenoid sinus","volume":"47","author":"Pasquini","year":"2004"},{"key":"b8-0040262","series-title":"Pediatr Pathol","doi-asserted-by":"publisher","first-page":"353","DOI":"10.3109\/15513818609068861","article-title":"Nasal gliomas and related brain heterotopias: a pathologist's perspective","volume":"5","author":"Patterson","year":"1986"},{"key":"b9-0040262","series-title":"Harefuah","first-page":"294","article-title":"[Management of nasal meningoencephaloceles and cerebrospinal rhinorrhea.]","volume":"140","author":"Puterman","year":"2001"},{"key":"b10-0040262","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/0090-3019(95)00199-9","article-title":"Evaluation of endoscopy in the treatment of rare meningoceles: preliminary results","volume":"44","author":"Raftopoulos","year":"1995"},{"key":"b11-0040262","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"308","DOI":"10.3171\/jns.1994.81.2.0308","article-title":"Endoscopic treatment of an oral cephalocele. 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