{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:39:41Z","timestamp":1783687181785,"version":"3.55.0"},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Spontaneous meningoencephaloceles of the lateral sphenoid sinus are rare lesions that are hypothesized to result from persistence of the lateral craniopharyngeal canal. Prior reports of the management of this lesion have been limited by its relative rarity. The objective of this paper is to report the theoretical etiology, surgical technique, and outcomes in patients undergoing endoscopic repair of spontaneous meningoencephalocele of the sphenoid sinus.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors conducted a retrospective review of a multiinstitutional series of 13 cases involving patients who underwent endoscopic repair of spontaneous meningoencephalocele of the lateral sphenoid sinus. The surgical technique and pathophysiological considerations are discussed.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The clinical manifestations included CSF rhinorrhea (85%), chronic headache (77%), and a history of meningitis (15%). The endoscopic approaches to the lateral sphenoid sinus were transnasal (39%), transpterygoid (23%), and transethmoid (39%). Two patients (8%) had postoperative CSF leaks, one of which closed spontaneously and one of which required revision endoscopic closure. All patients were free of leak at most recent follow-up. One patient experienced postoperative meningitis in the early postoperative period.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Endoscopic endonasal closure is an effective modality in the treatment of spontaneous meningoencephaloceles of the lateral sphenoid sinus. If the sphenoid sinus has extensive lateral pneumatization, adequate exposure may require a transpterygoid approach.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2009.7.jns0842","type":"journal-article","created":{"date-parts":[[2009,8,21]],"date-time":"2009-08-21T16:51:20Z","timestamp":1250873480000},"page":"1070-1077","source":"Crossref","is-referenced-by-count":81,"title":["Endoscopic management of spontaneous meningoencephalocele of the lateral sphenoid sinus"],"prefix":"10.3171","volume":"112","author":[{"given":"Abtin","family":"Tabaee","sequence":"first","affiliation":[{"name":"Departments of Otolaryngology\u2013Head and Neck Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay K.","family":"Anand","sequence":"additional","affiliation":[{"name":"Departments of Otolaryngology\u2013Head and Neck Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Cappabianca","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo","family":"Stamm","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Federal University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore H.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Neurosurgery, New York Presbyterian Hospital\u2013Weill Medical College of Cornell University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1121070","series-title":"Neurosurgery","first-page":"933","article-title":"Intrasphenoidal encephalocele: report of a case","volume":"22","author":"Abiko","year":"1988"},{"key":"b2-1121070","series-title":"Laryngoscope","first-page":"528","article-title":"Endoscopic transnasal transpterygopalatine fossa approach to the lateral recess of the sphenoid sinus","volume":"114","author":"Al-Nashar","year":"2004"},{"key":"b3-1121070","series-title":"Otolaryngol Head Neck Surg","first-page":"20","article-title":"Endoscopic transpterygoid approach to the lateral sphenoid recess: surgical approach and clinical experience","volume":"133","author":"Bolger","year":"2005"},{"key":"b4-1121070","series-title":"J Anat","first-page":"509","article-title":"Persistence of the so-called craniopharyngeal 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