{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:25:39Z","timestamp":1791127539749,"version":"4.1.0"},"reference-count":27,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Intramedullary spinal cord lipomas not associated with dysraphism are infrequently reported. When present, they typically occur in children and have a predilection for the cervical and thoracic spinal cord. The authors review the presentation, treatment, and disease course in 5 pediatric patients, and compare the outcomes with previously reported cases.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>With institutional review board approval, a retrospective chart review was undertaken at Childrens Hospital Los Angeles.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Four patients with intramedullary spinal cord lipomas and 1 patient with a lipoblastoma, none associated with dysraphism, were retrospectively reviewed. There were 2 boys and 3 girls ranging in age from 2 months to 4 years. Four patients underwent a laminectomy or laminoplasty with one or more subtotal resections. One patient initially underwent a decompressive laminoplasty without debulking. The median follow-up was 8 years (range 12 months\u201311 years). Two patients had regrowth of their lipoma, necessitating a second surgery in one patient and 3 debulking surgeries in the other. Postoperatively, 3 patients developed mild kyphosis, none significant enough to require orthopedic intervention. One patient underwent a stabilization procedure at the time of the initial laminectomy and tumor debulking. No patient received chemotherapy or radiation. At the most recent follow-up visit, patients demonstrated improved neurological function when compared with preoperative status.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>In addition to a decompressive laminectomy, debulking of the lipoma provides the best long-term neurological outcome. Gross-total excision is not warranted and usually is not possible. Long-term follow-up is needed, and repeat debulking of the lipoma is indicated if there is an increase in tumor size due to hyperplasia of residual adipocytes, when tumor growth is associated with neurological deterioration.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2009.9.peds09238","type":"journal-article","created":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T15:04:12Z","timestamp":1265036652000},"page":"172-178","source":"Crossref","is-referenced-by-count":27,"title":["Nondysraphic pediatric intramedullary spinal cord lipomas"],"prefix":"10.3171","volume":"5","author":[{"given":"Karen L.","family":"Fleming","sequence":"first","affiliation":[{"name":"Division of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Davidson","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Gonzalez-Gomez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Childrens Hospital Los Angeles; and"},{"name":"Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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