{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:04:47Z","timestamp":1790280287163,"version":"4.1.0"},"reference-count":18,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:p>Amoebic encephalitis is an uncommon and usually fatal condition. This case describes successful treatment of a <jats:italic>Balamuthia mandrillaris<\/jats:italic> brain abscess using prolonged antimicrobial agents with complete excision. It illustrates the risk of dissemination from cutaneous to cerebral amoebic lesions, potential progression with corticosteroid therapy, and the prospect for curative excision.<\/jats:p>","DOI":"10.3171\/2010.10.jns10677","type":"journal-article","created":{"date-parts":[[2010,11,12]],"date-time":"2010-11-12T13:31:10Z","timestamp":1289568670000},"page":"458-462","source":"Crossref","is-referenced-by-count":50,"title":["Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy"],"prefix":"10.3171","volume":"114","author":[{"given":"Joseph S.","family":"Doyle","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emer","family":"Campbell","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Fuller","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit and"},{"name":"Microbiology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis W.","family":"Spelman","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit and"},{"name":"Microbiology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhoda","family":"Cameron","sequence":"additional","affiliation":[{"name":"Pathology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Malham","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Gin","sequence":"additional","affiliation":[{"name":"Dermatology Unit, The Alfred Hospital;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon R.","family":"Lewin","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit and"},{"name":"Department of Medicine, Monash University; and"},{"name":"Burnet Institute, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns10677","series-title":"Clin Infect Dis","first-page":"1304","article-title":"Successful treatment of Balamuthia amoebic encephalitis: presentation of 2 cases","volume":"37","author":"Deetz","year":"2003"},{"key":"b2-jns10677","series-title":"JAMA","first-page":"2450","article-title":"Amoebic encephalitis due to Sappinia diploidea","volume":"285","author":"Gelman","year":"2001"},{"key":"b3-jns10677","series-title":"Arch Pathol Lab Med","first-page":"466","article-title":"Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome","volume":"128","author":"Jung","year":"2004"},{"key":"b4-jns10677","series-title":"J Neurosurg","first-page":"301","article-title":"Balamuthia mandrillaris meningoencephalitis in an immunocompromised patient. 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