{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:39:09Z","timestamp":1781653149806,"version":"3.54.5"},"reference-count":35,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Trigeminal neuralgia (TN) is a form of facial pain that can be debilitating if left untreated. It typically affects elderly adults and is thought to be related to neurovascular compression. It is uncommon in people younger than 30 years of age, with only 1% of cases reportedly occurring in those younger than 20 years of age. The most common cause of compression in young adults is thought to be venous nerve compression either alone or in association with arterial nerve compression. The objective of this study was to review data in cases of TN in which patients were 25 years of age or younger and to identify TN disease characteristics, demographics, clinical features, operative findings, and outcome.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors retrospectively reviewed the clinical records, surgical treatment, and long-term outcome in patients 25 years of age or younger with TN who underwent surgery performed by the senior author (K.J.B.) at Oregon Health &amp; Science University between 1995 and 2008.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Seven patients (2 males and 5 females) met the inclusion criteria. The average age at symptom onset was 19.6 \u00b1 3.4 years (\u00b1 SD) and the average age at surgery was 22.9 \u00b1 1.7 years. Six patients had right-sided symptoms and 1 had left-sided symptoms. Pain distribution was the V2 in 3 cases, V2\u20133 in 3 cases, and V3 in 1 case, with no cases of V1 affliction. A total of 11 procedures were performed in 7 patients, and 4 patients underwent a second procedure. Surgery and imaging revealed venous compression in all cases. The average follow-up period was 35.5 \u00b1 39.9 months (median 12 months). Three patients reported a good outcome (no pain with or without medications) and 4 reported a poor outcome (either no pain relief or mild pain relief after surgery).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Trigeminal neuralgia is uncommon in young adults. Patients tend to present with symptoms similar to those in adults: long periods of pain and venous compression, but outcome unfortunately is not as good as that reported in the older population.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2010.10.jns10781","type":"journal-article","created":{"date-parts":[[2010,12,3]],"date-time":"2010-12-03T15:00:24Z","timestamp":1291388424000},"page":"1306-1311","source":"Crossref","is-referenced-by-count":42,"title":["Trigeminal neuralgia in young adults"],"prefix":"10.3171","volume":"114","author":[{"given":"Diaa","family":"Bahgat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dibyendu K.","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"Raslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"McCartney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim J.","family":"Burchiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns10781","series-title":"Br J Surg","first-page":"306","article-title":"A case of trigeminal neuralgia in a boy, age 10 years, treated by intracranial division of the second and third divisions of the nerve","volume":"9","author":"Barclay","year":"1921"},{"key":"b2-jns10781","series-title":"N Engl J Med","first-page":"1077","article-title":"The long-term outcome of microvascular decompression for trigeminal neuralgia","volume":"334","author":"Barker","year":"1996"},{"key":"b3-jns10781","series-title":"J Neurosurg","first-page":"359","article-title":"Evaluation of 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A five-year follow-up study","volume":"22","author":"Kolluri","year":"1984"},{"key":"b20-jns10781","series-title":"Pediatr Neurol","first-page":"309","article-title":"Trigeminal neuralgia in children: two case reports","volume":"26","author":"Lopes","year":"2002"},{"key":"b21-jns10781","series-title":"Clin J Pain","first-page":"44","article-title":"\u201cNerve combing\u201d for trigeminal neuralgia without vascular compression: report of 10 cases","volume":"25","author":"Ma","year":"2009"},{"key":"b22-jns10781","series-title":"Pediatrics","first-page":"331","article-title":"Symptomatic trigeminal neuralgia in a 5-year-old child","volume":"60","author":"Marshall","year":"1977"},{"key":"b23-jns10781","series-title":"J Craniomandib Disord","first-page":"213","article-title":"Trigeminal neuralgia and its treatment in a 13-month-old child: a review and case report","volume":"5","author":"Mason","year":"1991"},{"key":"b24-jns10781","series-title":"J Neurosurg","first-page":"620","article-title":"Predictors of longterm success after microvascular decompression for trigeminal neuralgia. 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Case report","volume":"56","author":"Roski","year":"1982"},{"key":"b29-jns10781","series-title":"J Neurosurg","first-page":"1144","article-title":"Microvascular decompression for primary trigeminal neuralgia: long-term effectiveness and prognostic factors in a series of 362 consecutive patients with clear-cut neurovascular conflicts who underwent pure decompression","volume":"107","author":"Sindou","year":"2007"},{"key":"b30-jns10781","series-title":"Acta Neurochir (Wien)","first-page":"1235","article-title":"Microvascular decompression for primary Trigeminal Neuralgia (typical or atypical). Long-term effectiveness on pain; prospective study with survival analysis in a consecutive series of 362 patients","volume":"148","author":"Sindou","year":"2006"},{"issue":"4 Suppl 2","key":"b31-jns10781","series-title":"Neurosurgery","first-page":"ONS341","article-title":"Microvascular decompression for trigeminal neuralgia: the importance of a noncompressive technique\u2014Kaplan-Meier analysis in a consecutive series of 330 patients","volume":"63","author":"Sindou","year":"2008"},{"key":"b32-jns10781","series-title":"Stereotact Funct Neurosurg","first-page":"203","article-title":"Anatomical findings observed during microsurgical approaches of the cerebellopontine angle for vascular decompression in trigeminal neuralgia (350 cases)","volume":"63","author":"Sindou","year":"1994"},{"key":"b33-jns10781","series-title":"Acta Neurochir (Wien)","first-page":"144","article-title":"Long-term results of microvascular decompression for trigeminal neuralgia with reference to probability of recurrence","volume":"126","author":"Sun","year":"1994"},{"key":"b34-jns10781","series-title":"J Neurosurg","first-page":"14","article-title":"Decompression of the posterior trigeminal root in trigeminal neuralgia. A 30-year follow-up review","volume":"57","author":"Taarnh\u00f8j","year":"1982"},{"key":"b35-jns10781","series-title":"Acta Neurochir (Wien)","first-page":"243","article-title":"Various surgical modalities for trigeminal neuralgia: literature study of respective long-term outcomes","volume":"150","author":"Tatli","year":"2008"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/114\/5\/article-p1306.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/114\/5\/article-p1306.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/114\/5\/article-p1306.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T06:47:02Z","timestamp":1679899622000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/114\/5\/article-p1306.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":35,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/2010.10.jns10781","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}