{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T06:59:03Z","timestamp":1778569143542,"version":"3.51.4"},"reference-count":37,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Pediatric pineal region tumors are very difficult to cure surgically. The authors used the transcallosal interforniceal approach in patients with these lesions.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>One hundred fifty children, 98 boys and 52 girls, with pineal region tumors underwent tumor resection via the transcallosal interforniceal approach in the pediatric neurosurgery ward of TianTan Hospital. The patients ranged in age from 1 to 15 years. Fifty-eight patients had mature teratomas; 57, immature teratomas; 14, astrocytomas; 3, glioblastomas; 4, pineoblastomas; 2, pineocytomas; 4, choriocarcinomas; 4, cavernous hemangiomas; 2, germ cell tumors; and 2, epidermoid cysts.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>One hundred twenty-nine tumors were totally removed, 15 were subtotally removed, and 6 were partly removed. There were no deaths and no subsequent instances of disconnection syndrome. Short-term memory deficits appeared in 94 patients but resolved within 6 months in most; only a few patients retained persistent deficits. There were 2 patients with mutism that resolved within 10 days. Parinaud syndrome was observed in 45 patients after surgery; 21 of these cases had appeared preoperatively. The syndrome resolved within 6 months in 31 patients, while it remained in the other 14.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The transcallosal interforniceal approach appears to be a safe route for pineal region tumors in children, and complete resection can be achieved in the majority of patients.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2010.10.peds0976","type":"journal-article","created":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T14:36:41Z","timestamp":1293806201000},"page":"98-103","source":"Crossref","is-referenced-by-count":47,"title":["Transcallosal interforniceal approach to pineal region tumors in 150 children"],"prefix":"10.3171","volume":"7","author":[{"given":"Wenqing","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, TianTan Hospital, Capital University of Medical Science, Beijing, China; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenyu","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, TianTan Hospital, Capital University of Medical Science, Beijing, China; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle Yisha","family":"Liu","sequence":"additional","affiliation":[{"name":"Washington University in St. Louis, School of Medicine, St. Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, TianTan Hospital, Capital University of Medical Science, Beijing, China; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ge","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, TianTan Hospital, Capital University of Medical Science, Beijing, China; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiqing","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, TianTan Hospital, Capital University of Medical Science, Beijing, China; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0070098","series-title":"Cancer in the Nervous System","first-page":"193","article-title":"Pineal region tumors","author":"Allen","year":"2002"},{"key":"b2-0070098","series-title":"Clin Neurosurg","first-page":"499","article-title":"Surgery of masses affecting the third ventricular chamber: techniques and strategies","volume":"34","author":"Apuzzo","year":"1988"},{"key":"b3-0070098","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1227\/00006123-198205000-00001","article-title":"Transcallosal, interfornicial approaches for lesions affecting the third ventricle: surgical considerations and consequences","volume":"10","author":"Apuzzo","year":"1982"},{"key":"b4-0070098","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/BF01400496","article-title":"The transcallosal approach for lesions affecting the lateral and third ventricles. 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