{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T14:27:05Z","timestamp":1777300025318,"version":"3.51.4"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Cerebral sparganosis is a rare but underestimated parasitic disease caused by infestation by sparganum. It is difficult to make a confirmed preoperational diagnosis of this disease given the absence of characteristic clinical manifestations. A detailed protocol for the diagnosis and treatment of cerebral sparganosis is still lacking in the literature. In this article the authors set out comprehensive procedures for the diagnosis and treatment of cerebral sparganosis, describing the use of a stereotactic aspiration technique complemented by microsurgery based on experience gained from multiple cases.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The disease history, clinical manifestations, imaging features, and therapeutic procedures for 11 patients with cerebral sparganosis were retrospectively analyzed. Stereotactic aspiration procedures were performed in all 11 patients and were complemented by microsurgeries in 3 patients. The learning and experience gained from these treatments were summarized, and a comprehensive protocol for the diagnosis and treatment of cerebral sparganosis was reviewed.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Larvae of <jats:italic>Spirometra mansoni<\/jats:italic> were taken from all 11 patients: completely removed in 10 cases and partially removed in 1 case (discovered later). After surgery, clinical symptoms in all 11 patients were significantly improved. All epileptic symptoms were successfully cured, although in 1 case occasional seizures still occurred because of the incomplete removal of the larva. Muscle strength in the 4 patients who had hemiparesis prior to surgery recovered to normal. Symptoms in the 1 patient who had presented with partial body sensory disturbance resolved after surgery. There were no complications or deaths.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The authors concluded that an effective preoperative diagnosis of cerebral sparganosis can be made by detailed inquiry into the possible infection history and disease symptoms as well as careful scrutiny of characteristic radiological features and immunological testing results. In stereotactic operations performed to remove the larva, priority should be given to image-guided stereotactic aspiration given that it causes the smallest wounds. In cases in which stereotactic aspiration fails, stereotactic microsurgery should be performed to remove the larva. The surgeon must carefully avoid breaking the larva and leaving behind any larva residue during surgery.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2010.4.jns1079","type":"journal-article","created":{"date-parts":[[2010,5,21]],"date-time":"2010-05-21T11:45:45Z","timestamp":1274442345000},"page":"1421-1425","source":"Crossref","is-referenced-by-count":27,"title":["Diagnosis and stereotactic aspiration treatment of cerebral sparganosis: summary of 11 cases"],"prefix":"10.3171","volume":"114","author":[{"given":"Lei","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, No. 94 Hospital of People's Liberation Army, Nanchang, Jiangxi Province, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengju","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, No. 94 Hospital of People's Liberation Army, Nanchang, Jiangxi Province, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suokai","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, No. 94 Hospital of People's Liberation Army, Nanchang, Jiangxi Province, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns1079","series-title":"J Neurosurg","first-page":"1282","article-title":"Intracranial sparganosis: an uncommon infection. Case report","volume":"60","author":"Anders","year":"1984"},{"key":"b2-jns1079","series-title":"Neuroradiology","first-page":"1","article-title":"Cerebral sparganosis: analysis of 34 cases with emphasis on CT features","volume":"34","author":"Chang","year":"1992"},{"key":"b3-jns1079","series-title":"Radiology","first-page":"505","article-title":"Cerebral sparganosis: CT characteristics","volume":"165","author":"Chang","year":"1987"},{"key":"b4-jns1079","series-title":"J Magn Reson Imaging","first-page":"297","article-title":"MRI of CNS parasitic diseases","volume":"8","author":"Chang","year":"1998"},{"key":"b5-jns1079","series-title":"Korean J Parasitol","first-page":"15","article-title":"Histopathologic study on human sparganosis","volume":"18","author":"Chi","year":"1980"},{"key":"b6-jns1079","series-title":"Neurology","first-page":"1249","article-title":"Cerebral sparganosis","volume":"36","author":"Fan","year":"1986"},{"key":"b7-jns1079","series-title":"APMIS","first-page":"14","article-title":"Cutaneous sparganosis in France: the second case described from Europe. Case report","volume":"105","author":"Garin","year":"1997"},{"key":"b8-jns1079","series-title":"Rev Infect Dis","first-page":"155","article-title":"Cerebral sparganosis: case report and review","volume":"13","author":"Holodniy","year":"1991"},{"key":"b9-jns1079","series-title":"AJR Am J Roentgenol","first-page":"1084","article-title":"Abdominal sparganosis presenting as an abscess with fistulous communication to the bowel","volume":"185","author":"Lee","year":"2005"},{"key":"b10-jns1079","series-title":"J Neurosurg","first-page":"1066","article-title":"Cerebral sparganosis: clinical manifestations, treatment, and outcome","volume":"85","author":"Kim","year":"1996"},{"key":"b11-jns1079","series-title":"Korean J Parasitol","first-page":"222","article-title":"Serological diagnosis of human sparganosis by means of micro-ELISA","volume":"22","author":"Kim","year":"1984"},{"key":"b12-jns1079","series-title":"Korean J Parasitol","first-page":"195","article-title":"Differential expression of the 27 kDa cathepsin L-like cysteine protease in developmental stages of Spirometra erinacei","volume":"38","author":"Kong","year":"2000"},{"key":"b13-jns1079","series-title":"J Comput Assist Tomogr","first-page":"989","article-title":"MR and CT findings in cerebral sparganosis","volume":"17","author":"Kradel","year":"1993"},{"key":"b14-jns1079","series-title":"Clin Neurol Neurosurg","first-page":"148","article-title":"Sparganosis of brain and spinal cord: unusual tapeworm infestation (report of two cases)","volume":"100","author":"Kudesia","year":"1998"},{"key":"b15-jns1079","series-title":"Int J Parasitol","first-page":"29","article-title":"Studies on the sparganum of Spirometra erinacei. II Proteolytic enzymes(s) in the scolex","volume":"2","author":"Kwa","year":"1972"},{"key":"b16-jns1079","series-title":"Radiology","first-page":"751","article-title":"Cerebral sparganosis: MR imaging versus CT features","volume":"188","author":"Moon","year":"1993"},{"key":"b17-jns1079","series-title":"Am J Trop Med","first-page":"303","article-title":"Studies on sparganum mansonoides and sparganum proliferum","volume":"18","author":"Mueller","year":"1938"},{"key":"b18-jns1079","series-title":"Surg Neurol","first-page":"409","article-title":"Difficulty in diagnosing a case with apparent sequel cerebral sparganosis","volume":"67","author":"Murata","year":"2007"},{"key":"b19-jns1079","series-title":"Neurol Med Chir (Tokyo)","first-page":"164","article-title":"Surgical removal of a live worm by stereotactic targeting in cerebral sparganosis. Case report","volume":"46","author":"Nobayashi","year":"2006"},{"key":"b20-jns1079","series-title":"Br J Neurosurg","first-page":"784","article-title":"Cerebral sparganosis: a diagnostic challenge","volume":"22","author":"Rengarajan","year":"2008"},{"key":"b21-jns1079","series-title":"Neurology","first-page":"180","article-title":"Cerebral sparganosis: the wandering lesion","volume":"74","author":"Shirakawa","year":"2010"},{"key":"b22-jns1079","series-title":"AJNR Am J Neuroradiol","first-page":"1700","article-title":"CT and MR characteristics of cerebral sparganosis","volume":"28","author":"Song","year":"2007"},{"key":"b23-jns1079","series-title":"Parasitol Int","first-page":"73","article-title":"A case report of pleural sparganosis","volume":"46","author":"Tanaka","year":"1997"},{"key":"b24-jns1079","series-title":"J Neurosurg","first-page":"129","article-title":"Cerebral sparganosis diagnosed and treated with stereotactic techniques. 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