{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T07:54:42Z","timestamp":1785398082606,"version":"3.56.0"},"reference-count":62,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Whereas most pituitary adenomas are removable via the transsphenoidal approach, certain cases, such as dumbbell-shaped or suprasellar adenomas and recurrent and\/or fibrous tumors, remain difficult to treat. The authors present their experience with the extended endoscopic endonasal approach to the suprasellar area in managing this subset of tumors, which are classically treated through a transcranial route.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>From June 1997 to December 2008, 615 patients underwent endoscopic endonasal transsphenoidal surgery for pituitary adenomas in the Department of Neurosurgery of the Universit\u00e0 degli Studi di Napoli Federico II. Of this group, 20 patients with pituitary adenomas needed an extended endoscopic endonasal transtuberculum\/transplanum approach for tumor removal. Two surgical corridors were used during the transsphenoidal approach: 1) the conventional endosellar extraarachnoidal corridor and 2) a suprasellar transarachnoidal corridor.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The extent of resection was gross total in 12 (60%) of the 20 patients, near total in 4 (20%), subtotal in 3 (15%), and partial in 1 (5%). Postoperative CSF leakage occurred in 1 patient. One patient experienced worsening of temporal hemianopsia.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The authors' initial results with the extended endoscopic approach to the suprasellar area for selected pituitary adenomas are promising and may justify a widening of the current classical indications for transsphenoidal surgery.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2010.9.jns10262","type":"journal-article","created":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T13:59:52Z","timestamp":1288965592000},"page":"345-353","source":"Crossref","is-referenced-by-count":67,"title":["Extended endoscopic endonasal approach for selected pituitary adenomas: early experience"],"prefix":"10.3171","volume":"114","author":[{"given":"Salvatore","family":"Di Maio","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi M.","family":"Cavallo","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vita","family":"Stagno","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga Valeria","family":"Corriero","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Cappabianca","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Division of Neurosurgery, Universit\u00e0 degli Studi di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns10262","series-title":"Neurol Med Chir (Tokyo)","first-page":"830","article-title":"Staged transsphenoidal surgery for fibrous nonfunctioning pituitary adenomas with suprasellar extension","volume":"37","author":"Abe","year":"1997"},{"key":"b2-jns10262","series-title":"Surg Neurol","first-page":"380","article-title":"Combined transsphenoidal and pterional craniotomy approach to giant pituitary tumors","volume":"57","author":"Alleyne","year":"2002"},{"key":"b3-jns10262","series-title":"J Neurosurg Sci","first-page":"129","article-title":"The endoscopic endonasal trans-sphenoidal approach to the sellar and suprasellar area. 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