{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T09:06:25Z","timestamp":1780131985365,"version":"3.54.0"},"reference-count":90,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>Internal carotid artery dissection (ICAD) is a common cause of stroke in young patients, which may lead to major transient or permanent disability. Internal carotid artery dissection may occur spontaneously or after trauma and may present with a rapid neurological deterioration or with hemodynamic compromise and a delayed and unstable neurological deficit. Endovascular intervention using stent angioplasty can be used as an alternative to anticoagulation and open surgical therapy in this setting to restore blood flow through the affected carotid artery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The authors present the cases of 2 patients with flow-limiting symptomatic ICAD leading to near-complete occlusion and without sufficient collateral supply. Both patients had isolated cerebral hemispheres without significant blood flow from the anterior or posterior communicating arteries. In both cases, the patients demonstrated blood pressure\u2013dependent subacute unstable neurological deficits as a result of the hemodynamic compromise resulting from the dissection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both patients underwent careful microwire-based selection of the true lumen followed by confirmatory microinjection and subsequent exchange-length microwire-based recanalization using tandem telescoping endovascular stenting. In both cases the neurological state improved, and no permanent neurological deficit ensued.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The treatment of ICAD may be difficult in patients with subacute unstable neurological deficits related to symptomatic hypoperfusion, especially in the setting of a hemodynamically isolated hemisphere. Anticoagulation alone may be insufficient in these patients. Although there is no widely accepted guideline for the treatment of ICAD, the authors recommend stent-mediated endovascular recanalization in cases of symptomatic flow-limiting hemodynamic compromise, especially in cases of an isolated hemisphere lacking sufficient communicating artery compensatory perfusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2011.2.focus1139","type":"journal-article","created":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T10:16:04Z","timestamp":1306923364000},"page":"E16","source":"Crossref","is-referenced-by-count":14,"title":["Endovascular recanalization of symptomatic flow-limiting cervical carotid dissection in an isolated hemisphere"],"prefix":"10.3171","volume":"30","author":[{"given":"Clemens M.","family":"Schirmer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basar","family":"Atalay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel M.","family":"Malek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0300016","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1227\/01.NEU.0000311350.25281.6B","article-title":"Endovascular treatment of distal cervical and intracranial dissections with the neuroform stent","volume":"62","author":"Ansari","year":"2008"},{"key":"b2-0300016","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1097\/00006123-199904000-00037","article-title":"Treatment of symptomatic cervical carotid dissections with endovascular stents","volume":"44","author":"Bejjani","year":"1999"},{"key":"b3-0300016","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1161\/01.STR.26.2.235","article-title":"Time course of symptoms in extracranial carotid artery dissections. 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