{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:05:26Z","timestamp":1760267126118},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>The authors present a case illustrating the importance of obtaining a biopsy of any facial skin lesions in a patient presenting with an intracranial tumor involving the facial or trigeminal nerve. Conventional malignant melanoma metastasizes to the brain frequently and does not usually pose diagnostic difficulties. Direct intracranial spread of cutaneous melanoma is rare. In our patient, desmoplastic melanoma with perineural spread to the Meckel cave mimicked a malignant peripheral nerve sheath tumor clinically, radiographically, and histologically.<\/jats:p>","DOI":"10.3171\/2011.4.jns10913","type":"journal-article","created":{"date-parts":[[2011,5,6]],"date-time":"2011-05-06T14:28:09Z","timestamp":1304692089000},"page":"273-277","source":"Crossref","is-referenced-by-count":7,"title":["Perineural extension of cutaneous desmoplastic melanoma mimicking an intracranial malignant peripheral nerve sheath tumor"],"prefix":"10.3171","volume":"115","author":[{"given":"Samuel L.","family":"Barnett","sequence":"first","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Wells","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Texas Tech University Health Science Center, Lubbock, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Mickey","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimmo J.","family":"Hatanpaa","sequence":"additional","affiliation":[{"name":"Pathology, University of Texas Southwestern Medical Center, Dallas; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns10913","series-title":"Clin Dermatol","first-page":"564","article-title":"Unusual variants of malignant melanoma","volume":"27","author":"Barnhill","year":"2009"},{"key":"b2-jns10913","series-title":"J Neurooncol","first-page":"335","article-title":"Peripheral nerve tumors: management strategies and molecular insights","volume":"69","author":"Bhattacharyya","year":"2004"},{"key":"b3-jns10913","series-title":"AJNR Am J Neuroradiol","first-page":"5","article-title":"Perineural spread of malignant melanoma of the head and neck: clinical and imaging features","volume":"25","author":"Chang","year":"2004"},{"key":"b4-jns10913","series-title":"Cancer","first-page":"2345","article-title":"Neurosarcomatous transformation in malignant melanoma: an ultrastructural study","volume":"50","author":"DiMaio","year":"1982"},{"key":"b5-jns10913","series-title":"Cancer","first-page":"2143","article-title":"Perineural spread of cutaneous malignancy to the brain: a review of the literature and five patients treated with stereotactic radiotherapy","volume":"103","author":"Fowler","year":"2005"},{"key":"b6-jns10913","series-title":"Hum Pathol","first-page":"333","article-title":"Efficiently estimated histologic cell counts","volume":"25","author":"Going","year":"1994"},{"key":"b7-jns10913","series-title":"Arch Pathol Lab Med","first-page":"155","article-title":"Immunohistochemical evaluation of Leu-7, myelin basic-protein, S100-protein, glial-fibrillary acidic-protein, and LN3 immunoreactivity in nerve sheath tumors and sarcomas","volume":"112","author":"Johnson","year":"1988"},{"key":"b8-jns10913","series-title":"Melanoma Res","first-page":"438","article-title":"Melanocytic schwannoma of the cutaneous and subcutaneous tissues: three cases and a review of the literature","volume":"18","author":"Kaehler","year":"2008"},{"key":"b9-jns10913","series-title":"Histopathology","first-page":"1315","article-title":"An analysis of the sensitivity and specificity of the cytokeratin marker CAM 5.2 for epithelial tumours. 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