{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:19:07Z","timestamp":1762017547454},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>Endoscopic third ventriculostomy (ETV) is an accepted option in the treatment of obstructive hydrocephalus in children and is considered by many pediatric neurosurgeons to be the treatment of choice in this population. The procedure involves perforation of the floor of the third ventricle, specifically, the tuber cinereum, which is part of the hypothalamic-pituitary axis of cerebral endocrine regulation. Endocrine dysfunction, such as amenorrhea, weight gain, and precocious puberty, which are recognized only months to years after the procedure, may be underreported because patients and physicians may not relate the endocrine sequelae to the ETV. Few detailed reports of endocrinerelated complications following ETV exist to better understand these issues. In this study, the authors add to the literature with case descriptions of and correlative laboratory findings in 2 adolescent girls who underwent ETV for obstructive hydrocephalus and in whom amenorrhea subsequently developed.<\/jats:p>","DOI":"10.3171\/2011.6.peds1137","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T19:51:09Z","timestamp":1314906669000},"page":"325-328","source":"Crossref","is-referenced-by-count":8,"title":["Amenorrhea complicating endoscopic third ventriculostomy in the pediatric age group"],"prefix":"10.3171","volume":"8","author":[{"given":"Steven W.","family":"Hwang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Al-Shamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Whitehead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Curry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Dauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G.","family":"Luerssen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Jea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0080325","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1055\/s-2002-34339","article-title":"Intraoperative bradycardia and postoperative hyperkalemia in patients undergoing endoscopic third ventriculostomy","volume":"45","author":"Anandh","year":"2002"},{"key":"b2-0080325","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1136\/jnnp.71.2.268","article-title":"Neuropsychological and psychiatric complications in endoscopic third ventriculostomy: a clinical case report","volume":"71","author":"Benabarre","year":"2001"},{"key":"b3-0080325","series-title":"Eur Neurol","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1159\/000076793","article-title":"Amnesia following endoscopic third ventriculostomy: a single case study","volume":"51","author":"Bonanni","year":"2004"},{"key":"b4-0080325","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1159\/000028657","article-title":"Endoscopic third ventriculostomy: an outcome analysis","volume":"28","author":"Brockmeyer","year":"1998"},{"key":"b5-0080325","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/S0090-3019(01)00352-4","article-title":"Neuroendoscopic third ventriculostomy for hydrocephalus in adults: report of a single unit's experience with 63 cases","volume":"55","author":"Buxton","year":"2001"},{"key":"b6-0080325","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S0090-3019(03)00317-3","article-title":"Neuroendoscopic third ventriculostomy for failed shunts","volume":"60","author":"Buxton","year":"2003"},{"key":"b7-0080325","series-title":"Neurosurgery","first-page":"999","article-title":"Cerebral infarction after neuroendoscopic third ventriculostomy: case report","volume":"46","author":"Buxton","year":"2000"},{"key":"b8-0080325","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"239","DOI":"10.3171\/jns.1975.43.2.0239","article-title":"Deficiency of gonadotropin-releasing factor in a patient with hydrocephalus internus. Case report","volume":"43","author":"Coenegracht","year":"1975"},{"key":"b9-0080325","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1007\/s00381-007-0326-5","article-title":"Endocrine evaluation after endoscopic third ventriculostomy (ETV) in children","volume":"23","author":"Fritsch","year":"2007"},{"key":"b10-0080325","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3171\/2008.10.PEDS08148","article-title":"Changes in cerebral perfusion hormone profile and cerebrospinal fluid flow across the third ventriculostomy after endoscopic third ventriculostomy in patients with aqueductal stenosis: a prospective study. Clinical article","volume":"3","author":"Garg","year":"2009"},{"key":"b11-0080325","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1159\/000121242","article-title":"Treatment of hydrocephalus with third ventriculocisternostomy: outcome and CSF flow patterns","volume":"27","author":"Goumnerova","year":"1997"},{"issue":"1 Suppl 1","key":"b12-0080325","series-title":"Neurosurgery","first-page":"ONS168","article-title":"Complications of endoscopic third ventriculostomy in previously shunted patients","volume":"63","author":"Hader","year":"2008"},{"key":"b13-0080325","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1227\/00006123-199409000-00025","article-title":"A near-fatal complication of endoscopic third ventriculostomy: case report","volume":"35","author":"Handler","year":"1994"},{"key":"b14-0080325","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1097\/00006123-199904000-00062","article-title":"Endoscopic third ventriculostomy: outcome analysis of 100 consecutive procedures","volume":"44","author":"Hopf","year":"1999"},{"key":"b15-0080325","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.surneu.2003.07.001","article-title":"Chronic subdural hematoma as a complication of endoscopic third ventriculostomy","volume":"62","author":"Kim","year":"2004"},{"key":"b16-0080325","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s003810050485","article-title":"Surgical outcome of pediatric hydrocephalus treated by endoscopic III ventriculostomy: prognostic factors and interpretation of postoperative neuroimaging","volume":"16","author":"Kim","year":"2000"},{"key":"b17-0080325","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.3171\/jns.1996.85.6.1148","article-title":"Secondary amenorrhea due to hydrocephalus treated with endoscopic ventriculocisternostomy. Case report","volume":"85","author":"Lowry","year":"1996"},{"key":"b18-0080325","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1097\/00006123-199712000-00034","article-title":"Traumatic basilar aneurysm after endoscopic third ventriculostomy: case report","volume":"41","author":"McLaughlin","year":"1997"},{"key":"b19-0080325","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.3171\/jns.2002.96.6.1032","article-title":"Complications of endoscopic third ventriculostomy","volume":"96","author":"Schroeder","year":"2002"},{"key":"b20-0080325","series-title":"Childs Nerv Syst","first-page":"248","article-title":"Complications of endoscopic neurosurgery","volume":"12","author":"Teo","year":"1996"},{"key":"b21-0080325","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1055\/s-2000-11371","article-title":"Transient hyponatriemia complicated by seizures after endoscopic third ventriculostomy","volume":"43","author":"Vaicys","year":"2000"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/8\/3\/article-p325.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/8\/3\/article-p325.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/8\/3\/article-p325.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T15:52:22Z","timestamp":1681573942000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/8\/3\/article-p325.xml"}},"subtitle":["Report of 2 cases"],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":21,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2011.6.peds1137","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}