{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:08:48Z","timestamp":1789880928021,"version":"4.0.1"},"reference-count":58,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>Prospective examination of perioperative complications in spine surgery is limited in the literature. The authors prospectively collected data on patients who underwent spinal fusion at a tertiary care center and evaluated the effect of spinal fusion and comorbidities on perioperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between May and December 2008 data were collected prospectively in 248 patients admitted to the authors' institution for spine surgery. The 202 patients undergoing spine surgery with instrumentation were further analyzed in this report. Perioperative complications occurring within the initial 30 days after surgery were included. All adverse occurrences, whether directly related to surgery, were included in the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 114 (56.4%) of 202 patients experienced at least one perioperative complication. Instrumented fusions were associated with more minor complications (p = 0.001) and more overall complications (0.0024). Furthermore, in the thoracic and lumbar spine, complications increased based on the number of levels fused. Advanced patient age and certain comorbidities such as diabetes, cardiac disease, or a history of malignancy were also associated with an increased incidence of complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Using a prospective methodology with a broad definition of complications, the authors report a significantly higher perioperative incidence of complications than previously indicated after spinal fusion procedures. Given the increased application of instrumentation, especially for degenerative disease, a better estimate of clinically relevant surgical complications could aid spine surgeons and patients in an individualized complication index to facilitate a more thorough risk-benefit analysis prior to surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2011.7.focus1134","type":"journal-article","created":{"date-parts":[[2011,9,30]],"date-time":"2011-09-30T13:13:31Z","timestamp":1317388411000},"page":"E10","source":"Crossref","is-referenced-by-count":56,"title":["Complications related to instrumentation in spine surgery: a prospective analysis"],"prefix":"10.3171","volume":"31","author":[{"given":"Peter G.","family":"Campbell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Yadla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Malone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell G.","family":"Maltenfort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"Harrop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini D.","family":"Sharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Ratliff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0310010","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1097\/BRS.0b013e3181b03fe6","article-title":"Sagittal cervical alignment after cervical disc arthroplasty and anterior cervical discectomy and fusion: results of a prospective, randomized, controlled trial","volume":"34","author":"Anakwenze","year":"2009"},{"key":"b2-0310010","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/BF01407775","article-title":"Complications of anterior cervical discectomy without fusion in 450 consecutive patients","volume":"99","author":"Bertalanffy","year":"1989"},{"key":"b3-0310010","series-title":"J Neurotrauma","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1089\/neu.2007.0395","article-title":"Laminectomy and fusion after spinal cord injury: national inpatient complications and outcomes","volume":"25","author":"Boakye","year":"2008"},{"key":"b4-0310010","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3171\/2010.9.SPINE10151","article-title":"Comparison of ICD-9-based, retrospective, and prospective assessments of perioperative complications: assessment of accuracy in reporting. 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